Results 231 to 240 of about 78,400 (265)

Soluble E-Selectin in Arthritis

Clinical Immunology and Immunopathology, 1993
Cellular adhesion molecules, such as E-selectin, function to recruit leukocytes into inflammatory lesions. Recently, a soluble form of this adhesion molecule, sE-selectin, has been described. In this study we determined soluble E-selectin (sE-selectin) in synovial fluid (SF) and blood samples from patients with rheumatoid arthritis (RA) and other ...
A E, Koch   +3 more
openaire   +2 more sources

E-Selectin Binding Promotes Neutrophil Activationin Vivoin E-Selectin Transgenic Mice

Biochemical and Biophysical Research Communications, 1996
E-selectin is a membrane protein expressed by endothelial cells activated by cytokines released during the inflammatory process; it plays an important role in neutrophil emigration into inflamed tissues. To further explore in vivo the function of E-selectin, we have generated transgenic mouse line expressing E-selectin under the control of a chicken ...
Araki, Masatake   +6 more
openaire   +3 more sources

Selective E-selectin ligands

Blood, 2013
In this issue of Blood, Sreeramkumar and colleagues report that E-selectin ligand-1 (ESL-1) is a highly selective ligand for E-selectin on hematopoietic progenitors with unexpected important contributions to their trafficking.
openaire   +2 more sources

Potent E-Selectin Antagonists

Helvetica Chimica Acta, 2000
In the search for drugs that could control excessive leukocyte extravasation, we now report on modifications of the already known potent E-selectin antagonist 3 containing a cyclohexyllactic acid residue and a glucal-derived building block. Thus, we describe the synthesis and biological evaluation of a series of derivatives 6 with modified glucal ...
Rolf Bänteli   +5 more
openaire   +1 more source

Hypothermia Inhibits Human E-Selectin Transcription

Journal of Surgical Research, 1996
During endothelial cell activation, the formation and expression of E-selectin require transcriptional activation of the E-selectin gene, mediated by the coordinated action of several transcription factors and cis-acting elements in its 5'-flanking region.
T L, Haddix   +5 more
openaire   +2 more sources

Neutrophils roll on E-selectin.

The Journal of Immunology, 1993
Abstract Using flow conditions that simulate those in post capillary venules, we have found that neutrophils attach and roll on a substrate bearing purified E-selectin. E-selectin resembles P-selectin (CD62) with regard to the dependence of attachment efficiency on wall shear stress and selectin density.
M B, Lawrence, T A, Springer
openaire   +2 more sources

Human gingival keratinocytes express E‐selectin (CD62E)

Oral Diseases, 1996
OBJECTIVES: E‐selectin (CD62E) is an adhesion molecule that participates in the binding of leukocytes to activated blood vascular endothelium. The present study was undertaken to characterise the pattern of E‐selectin expression on epithelial cells of the gingival crevice and oral epithelium.METHODS: A panel of six anti‐E‐selectin monoclonal antibodies
Pietrzak, E. R.   +2 more
openaire   +3 more sources

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