Results 61 to 70 of about 50,139,323 (325)

E-selectin Mediates Immune Cell Trafficking in Corneal Transplantation

Transplantation, 2016
Background Immune rejection continues to threaten all tissue transplants. Here we sought to determine whether platelet (P)- and endothelial (E)-selectin mediate T cell recruitment in corneal transplantation and whether their blockade can reduce T cell ...
Thomas H. Dohlman, A. Di Zazzo, Masahiro Omoto, Jing Hua, Julia Ding, P. Hamrah, S. Chauhan, R. Dana   +7 more
semanticscholar   +1 more source

Loss of the endothelial glycocalyx is associated with increased E-selectin mediated adhesion of lung tumour cells to the brain microvascular endothelium

Journal of experimental & clinical cancer research : CR, 2015
BackgroundArrest of metastasising lung cancer cells to the brain microvasculature maybe mediated by interactions between ligands on circulating tumour cells and endothelial E-selectin adhesion molecules; a process likely to be regulated by the ...
S. Rai, Zaynab Nejadhamzeeigilani, N. Gutowski, J. Whatmore   +3 more
semanticscholar   +1 more source

Correlation between serum E-selectin levels and panoramic nailfold capillaroscopy in systemic sclerosis

Brazilian Journal of Medical and Biological Research, 2004
E-selectin is expressed by the activated endothelium and its plasma levels are increased in patients with systemic sclerosis. Eighteen patients fulfilling the American Rheumatism Association criteria for systemic sclerosis, 15 females and 3 males, 42-70 ...
V. Valim, L.S.S. Assis, M.F.J. Simões, V.F.M. Trevisani, M.L.C. Pucinelli, L.E.C. Andrade   +5 more
doaj   +1 more source

E-selectin ligand complexes adopt an extended high-affinity conformation

Journal of Molecular Cell Biology, 2015
E-selectin is a cell-adhesion molecule of the vascular endothelium that promotes essential leukocyte rolling in the early inflammatory response by binding to glycoproteins containing the tetrasaccharide sialyl Lewisx (sLex).
R. C. Preston, R. Jakob, F. Binder, C. P. Sager, B. Ernst, T. Maier   +5 more
semanticscholar   +1 more source

A cell-extrinsic ligand acquired by activated T cells in lymph node can bridge L-selectin and P-selectin [PDF]

, 2018
P-selectin expressed on activated endothelia and platelets supports recruitment of leukocytes expressing P-selectin ligand to sites of inflammation.
Michelle C Tra, Douglas A. Carlow (5916725), Michelle C. Tra (5916728), Hermann J Ziltener, Hermann J. Ziltener (361706), Douglas A Carlow   +5 more
core   +1 more source

Serum E-selectin and endothelial cell-specific Molecule-1 levels among people living with HIV on long term ART in Uganda: a pilot cross-sectional study

AIDS Research and Therapy, 2023
Background Prolonged exposure to HIV and anti-retroviral therapy (ART) has been linked with endothelial cell activation which subsequently predisposes people living with HIV (PLWH) to cardiovascular diseases.
Andrew Weil Semulimi, Charles Batte, Alice Bayiyana, Mariam Nakabuye, John Mukisa, Barbara Castelnuovo, Rosalind Parkes Ratanshi, Bruce J Kirenga, Isaac Ssinabulya   +8 more
doaj   +1 more source

Multitasking E selectin [PDF]

Science-Business eXchange, 2012
Researchers at the Mater Medical Research Institute, The University of Queensland and GlycoMimetics have mouse data showing that E selectin antagonists can alleviate side effects of chemotherapy brought about by exhaustion of the self-renewal capacity of hematopoietic stem cells.
openaire   +1 more source

Maternal, Fetal, and Placental Selectins in Women With Pre-eclampsia; Association With the Renin-Angiotensin-System

Frontiers in Medicine, 2020
Selectins [endothelial (E), platelet (P), and leucocytes (L)] are a class of cell adhesion molecules, stimulated in response to inflammation. Pre-eclampsia is characterized by inflammation, and angiotensin II is pro-inflammatory.
Hiten D. Mistry, Melissa V. Hott Ogalde, Fiona Broughton Pipkin, Geneviève Escher, Geneviève Escher, Lesia O. Kurlak   +5 more
doaj   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source