Results 51 to 60 of about 50,139,323 (325)

L1CAM as an E-selectin Ligand in Colon Cancer [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Metastasis is the main cause of death among colorectal cancer (CRC) patients. E-selectin and its carbohydrate ligands, including sialyl Lewis X (sLeX) antigen, are key players in the binding of circulating tumor cells to the endothelium, which is one of the major events leading to organ invasion. Nevertheless, the identity of the glycoprotein scaffolds
Fanny M. Deschepper   +8 more
openaire   +5 more sources

Serum and cerebrospinal fluid concentrations of E-selectin in patients with aneurysmal subarachnoid hemorrhage

open access: yesBrazilian Journal of Medical and Biological Research, 2005
The goal of the present study was to determine concentrations of E-selectin in both cerebrospinal fluid (CSF) and serum of patients with aneurysmal subarachnoid hemorrhage (SAH) and to evaluate the correlation between the clinical parameters and E ...
T. Tanriverdi   +6 more
doaj   +1 more source

Soluble P- and E-selectin levels as determinants of vaso-occlusive crises among sickle cell anemia patients in a tertiary hospital Northwestern Nigeria

open access: yesIraqi Journal of Hematology, 2020
BACKGROUND: Vascular E- and P-selectins play important roles in sickle cell anemia (SCA), vaso-occlusive crises (VOC); however, the extent to which they determine VOC has not been studied.
Sani Awwalu   +6 more
doaj   +1 more source

Higher Serum E-Selectin Levels Associated with Malignant Brain Edema after Endovascular Thrombectomy for Ischemic Stroke: A Pilot Study

open access: yesBrain Sciences, 2023
Background and Purpose: Little is known about the effect of soluble adhesion molecules on malignant brain edema (MBE) after endovascular thrombectomy (EVT).
Feng Zhou   +7 more
doaj   +1 more source

The effect of soluble E-selectin on tumor progression and metastasis

open access: yesBMC Cancer, 2016
Distant metastasis resulting from vascular dissemination of cancer cells is the primary cause of mortality from breast cancer. We have previously reported that E-selectin expression on the endothelial cell surface mediates shear-resistant adhesion and ...
Shin-Ae Kang   +12 more
semanticscholar   +1 more source

Towards the synthesis of a macrocyclic E-selectin antagonist [PDF]

open access: yes, 2006
Towards the Synthesis of a Macrocyclic E-selectin Antagonis: Introduction: Selectins are involved in the orderly migration of leukocytes from blood vessels to sites of inflammation.
Marti, Sébastien Jérôme Georges
core   +1 more source

E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1α/CXCR4. [PDF]

open access: yesPLoS ONE, 2013
OBJECTIVE: Endothelial-colony forming cells (ECFCs) can be readily expanded from human umbilical cord blood and can facilitate repair of endothelial injury.
Jie Sun   +4 more
doaj   +1 more source

Glycoengineering of E-selectin ligands by intracellular versus extracellular fucosylation differentially affects osteotropism of human mesenchymal stem cells

open access: yesStem Cells, 2016
Human mesenchymal stem cells (MSCs) hold great promise in cellular therapeutics for skeletal diseases but lack expression of E‐selectin ligands that direct homing of blood‐borne cells to bone marrow.
B. Dykstra   +7 more
semanticscholar   +1 more source

Characterization of equine E‐selectin

open access: yesImmunology, 2001
SummaryExpression of E‐selectin on activated endothelium is a critical initial step that leads to extravasation of leucocytes during inflammation, yet E‐selectin is largely uncharacterized in several animal species including the horse. We have sequenced and compared E‐selectin genes derived from activated cultures of purified equine (horse), cervid ...
J F, Hedges   +5 more
openaire   +3 more sources

Mucosal Administration of E-selectin Limits Disability in Models of Multiple Sclerosis

open access: yesFrontiers in Molecular Neuroscience, 2019
E-selectin plays an important role in mediating the rolling of leukocytes along and thus, the subsequent extravasation across activated endothelial cells comprising the microvasculature of the blood brain barrier (BBB).
Jacqueline A. Quandt   +3 more
doaj   +1 more source

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