Results 71 to 80 of about 21,662,479 (296)
A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats
Animal Models and Experimental Medicine, EarlyView.Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies +3 more
wiley +1 more source
Acta Medica IndonesianaBackground: Studies regarding hypercoagulation in Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) patients have produced conflicting results.
Syntia Nusanti +10 more
doaj +2 more sources
Frontiers in Cell and Developmental Biology, 2020 The interactions of leukemia cells with the bone marrow (BM) microenvironment is critical for disease progression and resistance to treatment. We have recently found that the vascular adhesion molecule E-(endothelial)-selectin is a key niche component ...
Johanna Erbani +4 more
doaj +1 more source
Intranasal delivery of E-selectin induces E-selectin specific regulatory cells.
, 2013 After 7 weeks on a high-fat diet, splenocytes were collected and cultured in X-vivo 15 alone or with 20 µg/ml E-selectin or 20 µg/ml OVA. Supernatant was collected at 72 h.
Xinhui Li (349485) +8 more
core +1 more source
E-selectin-monocyte interactions facilitate pulmonary metastasis [PDF]
, 2015 Metastasis is a multistep process depending on complex interactions between tumor cells and the stromal compartment which also contains immune cells and soluble factors such as chemokines.
Häuselmann, Irina
core +1 more source
Porcine kidney xenotransplantation: From primate models to clinical reality
Animal Models and Experimental Medicine, EarlyView.In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo +3 more
wiley +1 more source
, 2005 Objective. The two endothelial selectins, P- and E-selectin, are critically important for adhesion and homing of hematopoietic progenitor cells (HPC) into the bone marrow. Little is known, however, about the roles of these two selectins in hematopoiesis.
Levesque, Jean-Pierre +3 more
core +1 more source
Animal Models and Experimental Medicine, EarlyView.This graphical abstract illustrates the essential role of USB1 in neutrophil maturation. In normal myeloid cells, USB1 acts as an RNA exonuclease, trimming RNA tails to maintain proper RNA network function, which supports the differentiation of myeloid progenitor cells into mature neutrophils.
Hang Li +6 more
wiley +1 more source
Trends in Glycoscience and Glycotechnology, 1994 細胞接着分子であるセレクチンファミリーのE-、P-、L-セレクチンは、共通のドメイン構造を持ち、似たような糖鎖認識を行うので一つのファミリーとなっている。セレクチンはインテグリンや免疫グロブリン様の細胞接着分子と一緒になって、白血球の血管内皮細胞への接着に関与している。これらの接着分子の一過性発現と細胞に特異的な結合特性が白血球を召集して戦地である炎症部位に赴かせるのに役立っている。本論文は、E-セレクチンの構造、糖鎖結合性、および機能についての最近の論文の総説である。
openaire +2 more sources
Serum E-selectin specific antibodies.
, 2013 Serum was collected after 7 weeks on a high-fat diet. (A) Human E-selectin specific IgG1, IgG2a and total IgG in mice on regimen A (N = 5 per group) or regimen B (N = 24 for PBS group, N = 23 for E-selectin group).
Xinhui Li (349485) +8 more
core +1 more source