Results 31 to 40 of about 1,772 (177)

Acute and chronic effects of treatment with mesenchymal stromal cells on LPS-induced pulmonary inflammation, emphysema and atherosclerosis development.

PLoS ONE, 2017
BackgroundCOPD is a pulmonary disorder often accompanied by cardiovascular disease (CVD), and current treatment of this comorbidity is suboptimal. Systemic inflammation in COPD triggered by smoke and microbial exposure is suggested to link COPD and CVD ...
P Padmini S J Khedoe, Stan de Kleijn, Annemarie M van Oeveren-Rietdijk, Jaap J Plomp, Hetty C de Boer, Melissa van Pel, Patrick C N Rensen, Jimmy F P Berbée, Pieter S Hiemstra   +8 more
doaj   +1 more source

Complementation of Deletion of the Vaccinia Virus E3L Gene by theEscherichia coliRNase III Gene

Virology, 1997
This work investigated whether the Escherichia coli RNase III gene, rnc+, could complement vp1080, a mutant vaccinia virus that is deleted of its E3L gene. Like E3L, rnc+ codes for a dsRNA binding protein that contains an additional nucleolytic activity.
SHORS, TERI, JACOBS, BERTRAM L.
openaire   +2 more sources

Complementation of Vaccinia Virus Lacking the Double-Stranded RNA-Binding Protein Gene E3L by Human Cytomegalovirus [PDF]

Journal of Virology, 2002
ABSTRACT The cellular response to viral infection often includes activation of pathways that shut off protein synthesis and thereby inhibit viral replication. In order to enable efficient replication, many viruses carry genes such as the E3L gene of vaccinia virus that counteract these host antiviral pathways.
Stephanie J, Child, Sohail, Jarrahian, Victoria M, Harper, Adam P, Geballe   +3 more
openaire   +2 more sources

Use of a negative selectable marker for rapid selection of recombinant vaccinia virus

BioTechniques, 2011
Vaccinia virus has been a powerful tool in molecular biology and vaccine development. The relative ease of inserting and expressing foreign genes combined with its broad host range has made it an attractive antigen delivery system against many ...
Stacy D. White, Kip Conwell, Jeffrey O. Langland, Bertram L. Jacobs   +3 more
doaj   +1 more source

Role of viral factor E3L in modified vaccinia virus ankara infection of human HeLa Cells: regulation of the virus life cycle and identification of differentially expressed host genes.

, 2005
Modified vaccinia virus Ankara (MVA) is a highly attenuated virus strain being developed as a vaccine for delivery of viral and recombinant antigens. The MVA genome lacks functional copies of numerous genes interfering with host response to infection ...
Ludwig, H;Mages, J;Staib, C;Lehmann, MH;Lang, R;Sutter, G
core   +2 more sources

Variola virus E3L Zα domain, but not its Z-DNA binding activity, is required for PKR inhibition [PDF]

RNA, 2013
Responding to viral infection, the interferon-induced, double-stranded RNA (dsRNA)–activated protein kinase PKR phosphorylates translation initiation factor eIF2α to inhibit cellular and viral protein synthesis. To overcome this host defense mechanism, many poxviruses express the protein E3L, containing an N-terminal Z-DNA binding (Zα) domain and a C ...
Thakur, Meghna, Seo, Eun Joo, Dever, Thomas E.   +2 more
openaire   +2 more sources

Teacher Well‐Being Across Career Stages: An Ecological Study of Early‐ and Mid‐Career English Teachers in Japanese Secondary Schools

International Journal of Applied Linguistics, Volume 36, Issue 4, Page 3481-3492, November 2026.
ABSTRACT Teacher well‐being has garnered increasing attention in language education, as it plays a vital role in shaping both their professional lives and student learning. Although its importance is recognised, further research is still needed to gain a more comprehensive understanding of language teachers' well‐being.
Takeshi Onodera
wiley   +1 more source

Temporal Responses and Direct Encounters Among Native and Invasive Carnivores: Behavioral Evaluation Using Artificial Bait Sites

Journal of Zoology, Volume 330, Issue 2, Page 100-109, October 2026.
At artificial bait sites, raccoon dogs (Nyctereutes procyonoides) exhibited delayed temporal responses to red foxes (Vulpes vulpes) despite dominating direct encounters. In contrast, the invasive masked palm civet (Paguma larvata) showed no significant temporal responses toward either native species (raccoon dogs and red foxes), despite consistently ...
Hinako Takasaki, Masayuki U. Saito
wiley   +1 more source

Cholesteryl ester transfer protein decreases high-density lipoprotein and severely aggravates atherosclerosis in APOE*3-Leiden mice [PDF]

, 2006
OBJECTIVE - The role of cholesteryl ester transfer protein (CETP) in the development of atherosclerosis is still undergoing debate. Therefore, we evaluated the effect of human CETP expression on atherosclerosis in APOE*3-Leiden (E3L) mice with a ...
Jukema, J.W. (Jan Wouter), Offerman, Erik H, Dallinga-Thie, G.M. (Geesje), van der Hoogt, Caroline C, Jukema, J Wouter, Havekes, L.M. (Louis), Haan, W. (Willeke) de, Rensen, P.C.N. (Patrick), Dallinga-Thie, Geesje M, de Haan, Willeke, Offerman, E. (Erik), Westerterp, Marit; id_orcid, Westerterp, M. (Marit), Hoogt, C.C. (Caroline) van der, Havekes, Louis M, Rensen, Patrick C N, Westerterp, Marit   +16 more
core   +2 more sources

Haplotype of gene Nedd4 binding protein 2 associated with sporadic nasopharyngeal carcinoma in the Southern Chinese population

Journal of Translational Medicine, 2007
Background Bcl-3 as an oncoprotein is overexpressed in nasopharyngeal carcinoma (NPC). Nedd4 binding protein 2 (N4BP2), which is located in the NPC susceptibility locus, is a Bcl-3 binding protein.
Feng Qi-Sheng, Chen Li-Zhen, Zhang Ru-Hua, Yu Xing-Juan, Qin Hai-De, Zheng Mei-Zhen, Zeng Yi-Xin   +6 more
doaj   +1 more source