Results 51 to 60 of about 1,772 (177)
Conocimiento de las madres sobre la diarrea y su prevención
Las enfermedades diarreicas agudas constituyen un aspecto importante a conocer por las madres teniendo en cuenta su alta incidencia en todo el mundo.
Yuriena Reyes Tur, Yurelis Rey Camacho
doaj +4 more sources
Thalidomide-Based PROTACs: A Viable Strategy Against Trypanosomatids?
Background: In recent years, compounds known as Proteolysis Targeted Chimeras (PROTACs) have revitalized the field of bioactive molecule design. These compounds promote proteolysis of therapeutic targets by recruiting them to ubiquitin ligases.
Romina Manarin +7 more
doaj +1 more source
Large mammal recovery in the wake of human population decline
Human depopulation, particularly in rural areas, has contributed to the recovery of some large mammal populations. While recovery is generally good news for conservation, it can also lead to human‐wildlife conflict. We present several avenues to maximize coexistence in the face of further rural depopulation in other places. Read the free Plain Language
Alex J. Jensen +4 more
wiley +1 more source
Recently, we showed in APOE*3-Leiden cholesteryl ester transfer protein (E3L.CETP) mice that anacetrapib attenuated atherosclerosis development by reducing (V)LDL cholesterol [(V)LDL-C] rather than by raising HDL cholesterol.
Sam J.L. van der Tuin +11 more
doaj +1 more source
Evidence that vaccinia virulence factor E3L binds to Z-DNA in vivo : Implications for development of a therapy for poxvirus infection [PDF]
The E3L gene product found in all poxviruses is required for the lethality of mice in vaccinia virus infection. Both the C-terminal region, consisting of a double-stranded RNA-binding motif, and the N-terminal region (vZ E3L ), which is similar to the Zα family of Z-DNA-binding proteins, are ...
Yang-Gyun, Kim +4 more
openaire +3 more sources
Forecasting the Risk of Reinvasion by the Giant African Snail in Ogasawara, Japan
This study used SDMs constructed in multiple regions to predict the suitable habitats of Achatina fulica on Chichijima in the Ogasawara Islands. The model constructed on another island with a wide distribution range showed the highest predictive accuracy.
Mai Matsumoto, Takeshi Osawa
wiley +1 more source
Increasing evidence indicates that RNA interference (RNAi) may be used to provide antiviral immunity in mammalian cells. Human micro (mi)RNAs can inhibit the replication of a primate virus, whereas a virally-encoded miRNA from HIV inhibits its own ...
Clerzius Guerline +2 more
doaj +1 more source
ABSTRACT Spurred by the advancement of educational technology, more language instruction has been offered in online environments. Consequently, teaching practices have had to adapt to digital platforms. Accordingly, teachers’ provision of synchronous written corrective feedback (SWCF) on digital texts has received increasing attention.
Sanghee Kang, YouJin Kim, Minkyung Kim
wiley +1 more source
Characterization of the E3L Amino-Terminus in Poxvirus Replication and Tumor Regression [PDF]
: Host organisms have evolved multiple mechanisms to defend against a viral infection and likewise viruses have evolved multiple methods to subvert the host's anti-viral immune response.
core
Adaptive gene amplification as an intermediate step in the expansion of virus host range.
The majority of recently emerging infectious diseases in humans is due to cross-species pathogen transmissions from animals. To establish a productive infection in new host species, viruses must overcome barriers to replication mediated by diverse and ...
Greg Brennan +4 more
doaj +1 more source

