Results 51 to 60 of about 1,365 (152)
Tracking ebolavirus genomic drift with a resequencing microarray.
Filoviruses are emerging pathogens that cause acute fever with high fatality rate and present a global public health threat. During the 2013-2016 Ebola virus outbreak, genome sequencing allowed the study of virus evolution, mutations affecting ...
Irina Tiper +7 more
doaj +1 more source
Pathogenicity and Virulence of Ebolaviruses with Species- and Variant-specificity
Ebola virus (EBOV), belonging to the species Zaire ebolavirus in the genus Ebolavirus, causes a severe febrile illness in humans with case fatality rates (CFRs) up to 90%.
Satoko Yamaoka, Hideki Ebihara
doaj +1 more source
The Silent Risk of Sudan Virus: A Review Addressing Global Health Vulnerabilities
ABSTRACT Background and Aim Sudan Virus Disease (SVD) is a deadly hemorrhagic fever caused by the Sudan virus, first discovered in Sudan in 1976. This disease has been linked to several outbreaks in sub‐Saharan Africa, particularly in Uganda. The high fatality rate of SVD, ranging from 41% to 70%, emphasizes the critical need for effective preventive ...
Syed Masudur Rahman Dewan +1 more
wiley +1 more source
Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda.
Over the past 30 years, Zaire and Sudan ebolaviruses have been responsible for large hemorrhagic fever (HF) outbreaks with case fatalities ranging from 53% to 90%, while a third species, Côte d'Ivoire ebolavirus, caused a single non-fatal HF case.
Jonathan S Towner +17 more
doaj +1 more source
Abstract Japanese encephalitis virus (JEV), a zoonotic, mosquito‐borne virus, has broad circulation across the Central Indo‐Pacific biogeographical region (CIPBR) and has recently expanded dramatically within this region across southeastern Australia over the summer of 2021–2022.
Michael G. Walsh +2 more
wiley +1 more source
Background Uganda has experienced seven Ebola Virus Disease (EVD) outbreaks and four Marburg Virus Disease (MVD) outbreaks between 2000 and 2019. We investigated the seroprevalence and risk factors for Marburg virus and ebolaviruses in gold mining ...
Luke Nyakarahuka +10 more
doaj +1 more source
Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region.
The three human pathogenic ebolaviruses: Zaire (EBOV), Bundibugyo (BDBV), and Sudan (SUDV) virus, cause severe disease with high fatality rates. Epitopes of ebolavirus glycoprotein (GP) recognized by antibodies with binding breadth for all three ...
Clara T Schoeder +19 more
doaj +1 more source
Filoviruses, including marburgviruses and ebolaviruses, have a single transmembrane glycoprotein (GP) that facilitates their entry into cells. During entry, GP needs to be cleaved by host proteases to expose the receptor-binding site that binds to the ...
Manabu Igarashi +3 more
doaj +1 more source
Increasing Occurrence of Marburg Virus Outbreaks in Africa: Risk Assessment for Public Health
Bat and Marburg virus (Filovirus). Left: A Rousettus aegyptiacus bat; Center: a distribution map of R. aegyptiacus; Right: EM of Marburg virus. (figure credits: Left Wikipedia Nilflughund Lithuanian Zoological Gardens, Center; Center: Wikipedia Nilflughund IUCN Red List of Threatened Species, right Wikipedia Marburg virus CDC Fred Murphy; J.
Harald Brüssow
wiley +1 more source
Towards broad protection against Ebolaviruses
International audienceThe Ebola and Marburg viruses (from the filovirus family) induce deadly hemorrhagic fevers for which there is currently no licensed vaccine or treatment. Frequent outbreaks have occurred in sub-Saharan Africa, in humans and nonhuman
Sylvain Baize, Baize, Sylvain
core +1 more source

