Results 31 to 40 of about 1,365 (152)

Zoonotic and reverse zoonotic transmission of viruses between humans and pigs

APMIS, Volume 129, Issue 12, Page 675-693, December 2021., 2021
Humans and pigs share a close contact relationship, similar biological traits, and one of the highest estimated number of viruses compared to other mammalian species. The contribution and directionality of viral exchange between humans and pigs remain unclear for some of these viruses, but their transmission routes are important to characterize in ...
Helena Aagaard Glud, Sophie George, Kerstin Skovgaard, Lars Erik Larsen   +3 more
wiley   +1 more source

Filiviruses of southeast Asia, China and Europe (review)

Журнал инфектологии, 2019
Filoviruses are known as causative agents of severe haemorrhagic fevers with a high mortality rate in humans. Zaire ebolavirus and Marburgvirus, the most known of them, are associated with the occurrence of sporadic cases and outbreaks of hemorrhagic ...
A. M. Porshakov, Yu. V. Kononova, T. M. Luong   +2 more
doaj   +1 more source

Between virus correlations in the outcome of infection across host species: Evidence of virus by host species interactions

Evolution Letters, Volume 5, Issue 5, Page 472-483, October 2021., 2021
Abstract Virus host shifts are a major source of outbreaks and emerging infectious diseases, and predicting the outcome of novel host and virus interactions remains a key challenge for virus research. The evolutionary relationships between host species can explain variation in transmission rates, virulence, and virus community composition between hosts,
Ryan M. Imrie, Katherine E. Roberts, Ben Longdon   +2 more
wiley   +1 more source

Macrophage infection, activation, and histopathological findings in ebolavirus infection

Frontiers in Cellular and Infection Microbiology, 2022
Macrophages contribute to Ebola virus disease through their susceptibility to direct infection, their multi-faceted response to ebolaviruses, and their association with pathological findings in tissues throughout the body.
Timothy G. Wanninger, Timothy G. Wanninger, Daniel E. Millian, Omar A. Saldarriaga, Junki Maruyama, Takeshi Saito, Rachel A. Reyna, Satoshi Taniguchi, Esteban Arroyave, Melanie E. Connolly, Heather L. Stevenson, Slobodan Paessler   +11 more
doaj   +1 more source

Experimental Infection of Bundibugyo Virus in Domestic Swine Leads to Viral Shedding with Evidence of Intraspecies Transmission. [PDF]

Transbound Emerg Dis
The Ebolavirus genus contains several of the deadliest zoonotic viruses known. One of these, Bundibugyo virus (BDBV), has been the causative agent of two outbreaks of human disease that have resulted in 211 known cases with a case fatality rate of 33.6%.
Lewis CE, Pinette MM, Lakin SM, Smith G, Fisher M, Moffat E, Embury-Hyatt C, Pickering BS.   +7 more
europepmc   +2 more sources

Susceptibility of domestic pigs to experimental infection with ebolaviruses [PDF]

, 2022
The Ebolavirus genus contains several of the deadliest zoonotic viruses known. Though bats are routinely implicated as the possible reservoir host for the ebolaviruses, the involvement of other species in ecology of these viruses is unclear.
Lewis, Charles Elliott
core   +1 more source

Tolerance and Persistence of Ebola Virus in Primary Cells from Mops condylurus, a Potential Ebola Virus Reservoir

Viruses, 2021
Although there have been documented Ebola virus disease outbreaks for more than 40 years, the natural reservoir host has not been identified. Recent studies provide evidence that the Angolan free-tailed bat (Mops condylurus), an insectivorous microbat ...
Marcel Bokelmann, Uwe Vogel, Franka Debeljak, Ariane Düx, Silke Riesle-Sbarbaro, Angelika Lander, Annette Wahlbrink, Nicole Kromarek, Stuart Neil, Emmanuel Couacy-Hymann, Joseph Prescott, Andreas Kurth   +11 more
doaj   +1 more source

Ebolaviruses: Methods and Protocols

, 2017
This vital book collects key methods that have supported advancements in the field of ebolavirus molecular biology given the pressing need for the advancement of techniques for diagnostics, the development of vaccines and antivirals, and for furthering ...

core   +2 more sources

Combinatorial peptide-based epitope mapping from Ebola virus DNA vaccines and infections reveals residue-level determinants of antibody binding

Human Vaccines & Immunotherapeutics, 2017
Ebola virus (EBOV) infection is highly lethal and results in severe febrile bleeding disorders that affect humans and non-human primates. One of the therapeutic approaches for treating EBOV infection focus largely on cocktails of monoclonal antibodies ...
Daniel R. Ripoll, Daniel A. J. Mitchell, Lesley C. Dupuy, Anders Wallqvist, Connie Schmaljohn, Sidhartha Chaudhury   +5 more
doaj   +1 more source

Ebolaviruses: New roles for old proteins. [PDF]

PLoS Neglected Tropical Diseases, 2018
In 2014, the world witnessed the largest Ebolavirus outbreak in recorded history. The subsequent humanitarian effort spurred extensive research, significantly enhancing our understanding of ebolavirus replication and pathogenicity.
Diego Cantoni, Jeremy S Rossman
doaj   +1 more source