Results 21 to 30 of about 1,365 (152)
Cell Reports, 2021 Summary: Antibodies that target the glycan cap epitope on the ebolavirus glycoprotein (GP) are common in the adaptive response of survivors. A subset is known to be broadly neutralizing, but the details of their epitopes and basis for neutralization are ...
Charles D. Murin +16 more
doaj +1 more source
Bundibugyo Versus Zaire Ebolaviruses: Examination of the Polymerase Complex as a Therapeutic Target [PDF]
, 2021 Ebolaviruses, of the family Filoviridae, are the causative agents of outbreaks of hemorrhagic fever throughout Africa. In eastern Africa, three outbreak causing species of ebolavirus overlap in geographic distribution: Zaire ebolavirus (EBOV), Sudan ...
Levine, Corri B
core +3 more sources
mBio, 2021 Ebolaviruses Bundibugyo virus (BDBV) and Ebola virus (EBOV) cause fatal hemorrhagic disease in humans and nonhuman primates. While the host response to EBOV is well characterized, less is known about BDBV infection.
Courtney Woolsey +5 more
doaj +1 more source
Fruit-frugivore dependencies are important in <i>Ebolavirus</i> outbreaks in Sub-Saharan Africa. [PDF]
EcographyEbolaviruses have the ability to infect a wide variety of species, with many African mammals potentially serving either as primary reservoirs or secondary amplifying hosts. Previous work has shown that frugivorous bats and primates are often associated with spillover and outbreaks.
Sundaram M +8 more
europepmc +2 more sources
Israel Journal of Chemistry, Volume 63, Issue 1-2, February 2023., 2023 Abstract While most glycosidases that act on N‐linked glycans remove a single sugar residue at a time, endo‐α‐1,2‐mannosidases and endo‐α‐1,2‐mannanases of glycoside hydrolase family GH99 cut within a chain and remove two or more sugar residues.
Laura Burchill +4 more
wiley +1 more source
Large‐scale investigation of zoonotic viruses in the era of high‐throughput sequencing
Microbiology and Immunology, Volume 67, Issue 1, Page 1-13, January 2023., 2023 Abstract Zoonotic diseases considerably impact public health and socioeconomics. RNA viruses reportedly caused approximately 94% of zoonotic diseases documented from 1990 to 2010, emphasizing the importance of investigating RNA viruses in animals. Furthermore, it has been estimated that hundreds of thousands of animal viruses capable of infecting ...
Junna Kawasaki +2 more
wiley +1 more source
Conserved differences in protein sequence determine the human pathogenicity of Ebolaviruses. [PDF]
, 2015 Reston viruses are the only Ebolaviruses that are not pathogenic in humans. We analyzed 196 Ebolavirus genomes and identified specificity determining positions (SDPs) in all nine Ebolavirus proteins that distinguish Reston viruses from the four human ...
Michaelis, Martin +5 more
core +3 more sources
Transboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023 Ebola virus disease (EVD) is an acute viral hemorrhagic fever disease causing thousands of deaths. The large Ebola outbreak in 2014–2016 posed significant threats to global public health, requiring the development of multiple medical measures for disease control.
Shengnan Xu +12 more
wiley +1 more source
Tile diagram for all four Ebolaviruses.
, 2022 The genome and the eight coding sequences of Ebolaviruses are shown at the top. Beneath and aligned with the sequence content, are the tiles for each Ebolavirus. Note that greater variability among Sudan ebolavirus genomes required additional tiles, each
Moussa Kourout (12072040) +6 more
core +1 more source
Biological Reviews, Volume 97, Issue 1, Page 179-194, February 2022., 2022 ABSTRACT Collectively known as phytoplankton, photosynthetic microbes form the base of the marine food web, and account for up to half of the primary production on Earth. Haptophytes are key components of this phytoplankton community, playing important roles both as primary producers and as mixotrophs that graze on bacteria and protists.
Ruth‐Anne Sandaa +10 more
wiley +1 more source