Results 41 to 50 of about 17,768 (255)

Breakthrough Candidemia Due to Multidrug-Resistant Candida glabrata during Prophylaxis with a Low Dose of Micafungin [PDF]

open access: yes, 2014
We identified a case of breakthrough candidemia in a 25-year-old patient receiving micafungin prophylaxis (50 mg/day). Five Candida glabrata isolates were obtained from blood cultures and were classified as multidrug-resistant isolates, since all of them
Bizerra, Fernando Cesar   +6 more
core   +2 more sources

Analysis of molecular resistance to azole and echinocandin in Candida species in patients with vulvovaginal candidiasis [PDF]

open access: yesCurrent Medical Mycology, 2022
Background and Purpose: Vulvovaginal candidiasis (VVC) is considered the most common mucosal infection caused by Candida species. Azoles were considered the firstline treatment for VVC or recurrent vulvovaginal candidiasis (RVVC) in both healthy and ...
Ensieh Lotfali   +5 more
doaj   +1 more source

Candida auris, what do paediatricians need to know? [PDF]

open access: yes, 2018
AW is supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of Aberdeen.Peer reviewedPublisher ...
Warris, Adilia
core   +1 more source

New Horizons in Antifungal Therapy

open access: yesJournal of Fungi, 2016
Recent investigations have yielded both profound insights into the mechanisms required by pathogenic fungi for virulence within the human host, as well as novel potential targets for antifungal therapeutics.
Kaila M. Pianalto, J. Andrew Alspaugh
doaj   +1 more source

Treatment of Aspergillosis. [PDF]

open access: yes, 2018
Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
core   +1 more source

Translation inhibition by rocaglates activates a species-specific cell death program in the emerging fungal pathogen Candida auris [PDF]

open access: yes, 2020
Fungal infections are a major contributor to infectious disease-related deaths worldwide. Recently, global emergence of the fungal pathogen Candida auris has caused considerable concern because most C.
Brown, Lauren E.   +6 more
core   +1 more source

Polymorphic α‐Glucans as Structural Scaffolds in Cryptococcus Cell Walls for Chitin, Capsule, and Melanin: Insights From 13C and 1H Solid‐State NMR

open access: yesAngewandte Chemie, Volume 137, Issue 36, September 1, 2025.
Cryptococcus neoformans cell wall α‐1,3‐glucans as dual anchors for melanin and capsule: Solid‐state NMR of intact C. neoformans cells reveals five forms of α‐1,3‐glucans that structurally bridge melanin and capsule layers. These polysaccharides interact with chitin, chitosan, and β‐glucans to create a molecular scaffold that underlies virulence and ...
Ankur Ankur   +11 more
wiley   +2 more sources

Update 2016–2018 of the Nationwide Danish Fungaemia Surveillance Study: Epidemiologic Changes in a 15-Year Perspective

open access: yesJournal of Fungi, 2021
As part of a national surveillance programme initiated in 2004, fungal blood isolates from 2016–2018 underwent species identification and EUCAST susceptibility testing. The epidemiology was described and compared to data from previous years. In 2016–2018,
Malene Risum   +15 more
doaj   +1 more source

The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation [PDF]

open access: yes, 2017
We thank Cowen lab members for helpful discussions. We also thank David Rogers (University of Tennessee) for sharing microarray analysis of the CAS5 homozygous mutant, and Li Ang (University of Macau) for assistance in optimizing the ChIP-Seq experiments.
Andrews, Brenda J   +18 more
core   +2 more sources

Kajian Molekuler Resistensi Candida Albicans Terhadap Antifungi [PDF]

open access: yes, 2014
Candida albicans is one of the species Candida which mostly cause infection in human. Antifungal agent azole, polyene, echinocandin, and flucytosine are commonly used for Candida albicans infection treatment.
Candrasari, D. S. (Damiana)
core   +3 more sources

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