Results 41 to 50 of about 13,766 (257)

Novel Cell Wall Antifungals Reveal a Special Synergistic Activity in pbr1 Mutants Resistant to the Glucan Synthesis Antifungals Papulacandins and Echinocandins

open access: yesFrontiers in Microbiology, 2019
A series of 4-(arylmethylene)-3-isochromanones have been prepared with base-catalyzed Knoevenagel condensation starting from 3-isochromanone and aromatic aldehydes.
Rodrigo Berzaghi   +6 more
doaj   +1 more source

Titan cell production in Cryptococcus neoformans reshapes the cell wall and capsule composition during infection [PDF]

open access: yes, 2018
This work was supported by the National Institutes of Health (R01AI080275 and R21AI22352), the NIH Fogarty International Center (R25TW009345), the University of Minnesota Center for Translational Science Institute (UL1TR000114), Wellcome Trust (086827 ...
Gow, Neil A R   +5 more
core   +1 more source

Review on Current Status of Echinocandins Use [PDF]

open access: yesAntibiotics, 2020
Fungal infections are rising all over the world every year. There are only five medical compound classes for treatment: triazoles, echinocandins, polyenes, flucytosine and allylamine. Currently, echinocandins are the most important compounds, because of their wide activity spectrum and much lower sides effects that may occur during therapy with other ...
Martyna Mroczyńska   +1 more
openaire   +4 more sources

Breakthrough Candidemia Due to Multidrug-Resistant Candida glabrata during Prophylaxis with a Low Dose of Micafungin [PDF]

open access: yes, 2014
We identified a case of breakthrough candidemia in a 25-year-old patient receiving micafungin prophylaxis (50 mg/day). Five Candida glabrata isolates were obtained from blood cultures and were classified as multidrug-resistant isolates, since all of them
Bizerra, Fernando Cesar   +6 more
core   +2 more sources

Navigating the New Reality: A Review of the Epidemiological, Clinical, and Microbiological Characteristics of Candida auris, with a Focus on Children

open access: yesJournal of Fungi, 2023
During the past decade, Candida auris emerged across the world, causing nosocomial outbreaks in both pediatric and adult populations, particularly in intensive care settings.
Liat Ashkenazi-Hoffnung   +1 more
doaj   +1 more source

Antimicrobial activity, synergism and inhibition of germ tube formation by Crocus sativus-derived compounds against Candida spp [PDF]

open access: yes, 2016
The limited arsenal of synthetic antifungal agents and the emergence of resistant Candida strains have prompted the researchers towards the investigation of naturally occurring compounds or their semisynthetic derivatives in order to propose new ...
ANGIOLELLA, Letizia   +4 more
core   +2 more sources

Gel Formulations with an Echinocandin for Cutaneous Candidiasis: The Influence of Azone and Transcutol on Biopharmaceutical Features

open access: yesGels, 2023
Caspofungin is a drug that is used for fungal infections that are difficult to treat, including invasive aspergillosis and candidemia, as well as other forms of invasive candidiasis.
Noelia Pérez-González   +8 more
doaj   +1 more source

Cell wall stress induces alternative fungal cytokinesis and septation strategies [PDF]

open access: yes, 2013
Peer reviewedPublisher ...
Gow, Neil A R   +4 more
core   +1 more source

A Hadal Streptomyces-Derived Echinocandin Acylase Discovered through the Prioritization of Protein Families

open access: yesMarine Drugs
Naturally occurring echinocandin B and FR901379 are potent antifungal lipopeptides featuring a cyclic hexapeptide nucleus and a fatty acid side chain.
Xuejian Jiang   +5 more
doaj   +1 more source

Hsp21potentiates antifungal drug tolerance in Candida albicans [PDF]

open access: yes, 2013
Peer reviewedPublisher ...
Alix Therese Coste   +52 more
core   +2 more sources

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