Results 71 to 80 of about 13,766 (257)

Clade Distinction and Tracking of Clonal Spread by Fourier‐Transform Infrared Spectroscopy in Multicenter Candida (Candidozyma) auris Outbreak

Mycoses, Volume 68, Issue 7, July 2025.
ABSTRACT Background Candida (Candidozyma) auris has distinct genetic clades. Clade distinction is relevant for infection control and epidemiological purposes. State‐of‐the‐art typing methodologies for clade distinction are based on genomic approaches, such as short tandem repeat (STR) analysis and whole‐genome sequencing (WGS).
Camylla C. de Melo, Halana L. N. L. de Oliveira, Bruna R. Souza, Carla V. R. Moura, Rodrigo Oliveira, Rafael W. Bastos, Karoline Kristina Kemmerich, João N. de Almeida‐Júnior, Arnaldo Lopes Colombo, Bram Spruijtenburg, Jacques F. Meis, Patrice Le Pape, Carolyn G. J. Moonen, Reginaldo G. de Lima‐Neto   +13 more
wiley   +1 more source

Treatment of invasive candidiasis with echinocandins [PDF]

Mycoses, 2009
SummaryBlood stream infections by Candida spp. represent the majority of invasive fungal infections in intensive care patients. The high crude mortality of invasive candidiasis remained essentially unchanged during the last two decades despite new treatment options that became available.
Angela Steinbach, Jörg J. Vehreschild, Oliver A. Cornely, Andreas Glöckner   +3 more
openaire   +3 more sources

Antimicrobial susceptibility and clinical outcomes of Candida parapsilosis bloodstream infections in a tertiary teaching hospital in Northern Taiwan [PDF]

, 2015
BackgroundCandida parapsilosis is an emerging non-albicans Candida that is associated with central line-associated infection. C. parapsilosis has higher minimal inhibitory concentration to echinocandin than Candida albicans, and the effects of ...
Hsieh, Feng-Chih, Lee, Chun-Ming, Lin, Chih-Chen, Liu, Chang-Pan, Wang, Wei-Sheng   +4 more
core   +1 more source

Biosynthesis of the Fungal Cyclic Lipodepsipeptide Pleosporacin, a New Selective Inhibitor of the Phytopathogen Botrytis cinerea

ChemBioChem, Volume 26, Issue 12, June 16, 2025.
Bioactivity‐guided isolation led to the discovery of a potent and selective inhibitor of the phytopathogen Botrytis cinerea, pleosporacin (1), from mycelia extracts of the fungal strain Pleosporales sp. IBWF 020‐21. The biosynthesis of the nonribosomal cyclic lipodepsipeptide 1 was elucidated via heterologous reconstitution in Aspergillus oryzae ...
Carsten Wieder, Rainer Wiechert, Alexander Yemelin, Louis Pergaud Sandjo, Eckhard Thines, Till Opatz, Anja Schüffler   +6 more
wiley   +1 more source

Breakthrough Bloodstream Infections Caused by Echinocandin-Resistant Candida tropicalis: An Emerging Threat to Immunocompromised Patients with Hematological Malignancies

Journal of Fungi, 2020
Background. Candida tropicalis is a virulent fungal pathogen for which echinocandins are the primary therapy. Emergence of resistance to echinocandins of C. tropicalis carries potentially ominous therapeutic implications. Methods.
Maroun M. Sfeir, Cristina Jiménez-Ortigosa, Maria N. Gamaletsou, Audrey N. Schuetz, Rosemary Soave, Koen Van Besien, Catherine B. Small, David S. Perlin, Thomas J. Walsh   +8 more
doaj   +1 more source

Echinocandin inhibition of 1,3-β-D-glucan synthase from Candida albicans [PDF]

, 1984
The cyclic peptide antibiotic echinocandin was found to inhibit 1,3-β-D-glucan synthase activity present in a mixed membrane fraction from Candida albicans. Addition of antibiotic reduced the Vmax of the enzyme, but the Km was unaffected.
Kerridge, D., Perry, H., Sawistowska-Schröder, E.T.   +2 more
core   +1 more source

Encephalopathy and Endophthalmitis Following Device‐Related Invasive Clavispora Lusitaniae Infection in an Immunocompetent Patient: A Case Report

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT Device‐related Candida infections are becoming more prevalent, even among immunocompetent individuals. For patients diagnosed with invasive candidiasis, it is essential to perform a fundoscopic examination, irrespective of the presence of ocular symptoms.
Yi Cui, Zhenxing Huang, Hui Han, Yang Ma, Shanshan Li, Yuanyuan Hu, Hui Zhang, Xuehai Zhang, Xiuhe Zhao, Dexin Yu, Jianqiao Li, Han Liu, Chen Li, Hao Wang   +13 more
wiley   +1 more source

The Long-Acting Echinocandin, Rezafungin, Prevents Pneumocystis Pneumonia and Eliminates Pneumocystis from the Lungs in Prophylaxis and Murine Treatment Models

Journal of Fungi, 2021
Rezafungin is a novel echinocandin in Phase 3 development for prevention of invasive fungal disease caused by Candida spp., Aspergillus spp. and Pneumocystis jirovecii in blood and marrow transplantation patients.
Melanie T. Cushion, Alan Ashbaugh
doaj   +1 more source

Antiviral Activity of Micafungin and Its Derivatives against SARS-CoV-2 RNA Replication

Viruses, 2023
Echinocandin antifungal drugs, including micafungin, anidulafungin, and caspofungin, have been recently reported to exhibit antiviral effects against various viruses such as flavivirus, alphavirus, and coronavirus. In this study, we focused on micafungin
Shogo Nakajima, Hirofumi Ohashi, Daisuke Akazawa, Shiho Torii, Rigel Suzuki, Takasuke Fukuhara, Koichi Watashi   +6 more
doaj   +1 more source

The seizure of illicit assets: patterns of civil forfeiture in Canada and Ireland [PDF]

, 2013
No description ...
Gallant, M Michelle, King, Colin
core   +1 more source