Results 71 to 80 of about 17,768 (255)
Caspofungin Induced Cell Wall Changes of Candida Species Influences Macrophage Interactions
Frontiers in Cellular and Infection Microbiology, 2020 Candida species are known to differ in their ability to cause infection and have been shown to display varied susceptibilities to antifungal drugs. Treatment with the echinocandin, caspofungin, leads to compensatory alterations in the fungal cell wall ...
Louise A. Walker, Carol A. Munro
doaj +1 more source
Frontiers in Microbiology, 2021 Fungal infections are on the rise, and emergence of drug-resistant Candida strains refractory to treatment is particularly alarming. Resistance to azole class antifungals, which have been extensively used worldwide for several decades, is so high in ...
Rocio Garcia-Rubio +8 more
doaj +1 more source
Sentinel Case of Candida auris in the Western United States Following Prolonged Occult Colonization in a Returned Traveler from India. [PDF]
, 2019 Candida auris is an emerging multidrug-resistant yeast with high mortality. We report the sentinel C. auris case on the United States West Coast in a patient who relocated from India.
Crawford, Emily D +12 more
core +1 more source
New cell wall-affecting antifungal antibiotics [PDF]
, 2013 Capítulo 9.Fungi have emerged worldwide as increasingly frequent causes of healthcare-associated infections. Invasive fungal infections can be life-threatening.
Cortés, Juan Carlos G. +2 more
core +2 more sources
Angewandte Chemie, Volume 137, Issue 35, August 25, 2025.Understanding the mode of action is critical to develop new antifungal drugs. Solid‐state NMR was used to study the reorganization of the Aspergillus fumigatus cell wall by a host‐defence peptide. We identified specific polysaccharides and amino acids that are affected by the peptide.
Ajit Kumar Bishoyi +5 more
wiley +2 more sources
Drug-Resistant Fungi: An Emerging Challenge Threatening Our Limited Antifungal Armamentarium
Antibiotics, 2020 The high clinical mortality and economic burden posed by invasive fungal infections (IFIs), along with significant agricultural crop loss caused by various fungal species, has resulted in the widespread use of antifungal agents.
Amir Arastehfar +8 more
doaj +1 more source
Continual Decline in Azole Susceptibility Rates in Candida tropicalis Over a 9-Year Period in China
Frontiers in Microbiology, 2021 BackgroundThere have been reports of increasing azole resistance in Candida tropicalis, especially in the Asia-Pacific region. Here we report on the epidemiology and antifungal susceptibility of C. tropicalis causing invasive candidiasis in China, from a
Yao Wang +172 more
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Journal of Fungi, 2020 Background. Candida tropicalis is a virulent fungal pathogen for which echinocandins are the primary therapy. Emergence of resistance to echinocandins of C. tropicalis carries potentially ominous therapeutic implications. Methods.
Maroun M. Sfeir +8 more
doaj +1 more source
Can Intravenous Antifungal therapy be safely used in the Outpatient Parenteral Antimicrobial Therapy (OPAT) setting? [PDF]
, 2019 Outpatient parenteral antimicrobial therapy (OPAT) is an established treatment option for patients with a variety of infections who require a period of intravenous therapy, are clinically stable, and do not require continuous monitoring.
Kenny, Claire +2 more
core +2 more sources
Clinical Case Reports, Volume 13, Issue 9, September 2025.ABSTRACT We report on a case of a patient in their early 60's with a history of traumatic brain injury, decompressive cranioplasty, and chronic ventriculoperitoneal (VP) shunt who presented from a nursing home with altered mental status and status epilepticus.
Christine A. Vu +2 more
wiley +1 more source