Results 71 to 80 of about 23,261 (287)

Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrata

Journal of Fungi, 2018
Candida glabrata has thoroughly adapted to successfully colonize human mucosal membranes and survive in vivo pressures. prior to and during antifungal treatment. Out of all the medically relevant Candida species, C.
Kelley R. Healey, David S. Perlin
doaj   +1 more source

Kajian Molekuler Resistensi Candida Albicans Terhadap Antifungi [PDF]

, 2014
Candida albicans is one of the species Candida which mostly cause infection in human. Antifungal agent azole, polyene, echinocandin, and flucytosine are commonly used for Candida albicans infection treatment.
Candrasari, D. S. (Damiana)
core   +3 more sources

Genomic description of acquired fluconazole- and echinocandin-resistance in patients with serial Candida glabrata isolates

Journal of Clinical Microbiology
Candida glabrata is one of the most common causes of systemic candidiasis, often resistant to antifungal medications. To describe the genomic context of emerging resistance, we conducted a retrospective analysis of 82 serially collected isolates from 33 ...
E. Misas, E. Seagle, E. Jenkins, M. Rajeev, S. Hurst, N. Nunnally, M. Bentz, M. Lyman, E. Berkow, L. H. Harrison, W. Schaffner, T. M. Markus, R. Pierce, M. Farley, N. Chow, S. Lockhart, A. Litvintseva   +16 more
semanticscholar   +1 more source

Invasive Fungal Breakthrough Infections under Targeted Echinocandin Prophylaxis in High-Risk Liver Transplant Recipients

Journal of Fungi, 2023
Invasive fungal infections (IFIs) are frequent and outcome-relevant complications in the early postoperative period after orthotopic liver transplantation (OLT).
Robert Breitkopf, Benedikt Treml, Thomas Senoner, Zoran Bukumirić, Sasa Rajsic   +4 more
doaj   +1 more source

Resistance in Candida albicans: exploring the cell wall barrier by proteomics [PDF]

, 2015
The incidence of candidiasis has dramatically increased and bloodstream infections due to different species of Candida are becoming a prime cause of morbidity and mortality in different types of immunocompromised patients.
Angiolella, Letizia, Maras, Bruno, Mignogna, Giuseppina   +2 more
core   +1 more source

Development of High-Level Echinocandin Resistance in a Patient With Recurrent Candida auris Candidemia Secondary to Chronic Candiduria

Open Forum Infectious Diseases, 2019
Objective Candida auris is a globally emerging pathogen associated with significant mortality. This pathogen frequently is misidentified by traditional biochemical methods and is resistant to commonly used antifungals.
M. Biagi, N. Wiederhold, C. Gibas, B. Wickes, V. Lozano, S. Bleasdale, L. Danziger   +6 more
semanticscholar   +1 more source

Recent Insights into the Paradoxical Effect of Echinocandins

Journal of Fungi, 2017
Echinocandin antifungals represent one of the most important drug classes for the treatment of invasive fungal infections. The mode of action of the echinocandins relies on inhibition of the β-1,3-glucan synthase, an enzyme essentially required for the ...
Johannes Wagener, Veronika Loiko
doaj   +1 more source

Genetic Basis of Azole and Echinocandin Resistance in Clinical Candida glabrata in Japan

Antimicrobial Agents and Chemotherapy, 2020
Infections caused by Candida glabrata have caused worldwide concern, especially when they are associated with increasing echinocandin and azole resistance.
H. Khalifa, Teppei Arai, Hidetaka Majima, A. Watanabe, K. Kamei   +4 more
semanticscholar   +1 more source

In Vitro Activities of Five Antifungal Drugs Against Conidia and Sclerotic Cells of Chromoblastomycosis Agent Fonsecaea spp

Microbiology and Immunology, EarlyView.
ABSTRACT Chromoblastomycosis (CBM) is a chronic skin and subcutaneous infection mainly caused by Fonsecaea pedrosoi, a dematiaceous fungus with various morphotypes. Characteristic sclerotic cells—globe‐shaped, multiseptated and pigmented—are found in lesions of infected individuals, though their differentiation in the host remains poorly understood. To
Aline Barral Takahashi, Daniella Paternostro de Araújo Grisólia, Moises Batista da Silva, Naila Ferreira da Cruz, Sâmela Miranda da Silva, Patrícia Fagundes da Costa, Claudio Guedes Salgado   +6 more
wiley   +1 more source

The seizure of illicit assets: patterns of civil forfeiture in Canada and Ireland [PDF]

, 2013
No description ...
Gallant, M Michelle, King, Colin
core   +1 more source