Results 101 to 110 of about 8,703 (161)

In vivo evolution to echinocandin resistance and increasing clonal heterogeneity in Candida auris during a difficult-to-control hospital outbreak, Italy, 2019 to 2022. [PDF]

Euro Surveill, 2023
Codda G, Willison E, Magnasco L, Morici P, Giacobbe DR, Mencacci A, Marini D, Mikulska M, Bassetti M, Marchese A, Di Pilato V.   +10 more
europepmc   +1 more source

Echinocandins: Resistance Mechanisms [PDF]

, 2015
Santosh Katiyar, Thomas Edlind
openaire   +1 more source

Transcriptomics and Phenotyping Define Genetic Signatures Associated with Echinocandin Resistance in Candida auris. [PDF]

mBio, 2022
Jenull S, Shivarathri R, Tsymala I, Penninger P, Trinh PC, Nogueira F, Chauhan M, Singh A, Petryshyn A, Stoiber A, Chowdhary A, Chauhan N, Kuchler K.   +12 more
europepmc   +1 more source

Emergence of multidrug-resistant Candidozyma auris in southern China: a multicenter study on genetic diversity and antifungal resistance

Frontiers in Microbiology
PurposeCandidozyma auris (C. auris) is an emerging fungal pathogen that is resistant to multiple drugs and poses a serious threat to global health. This study aimed to investigate the genetic diversity and antifungal resistance profiles of C.
Penghao Guo, Jingchun Fang, Ruizhi Wang, Weihong Lin, Yueting Jiang, Jun Long, Lingjuan Chen, Xudong Huang, Kang Liao, Yaqin Peng   +9 more
doaj   +1 more source

The role of aneuploidy in the emergence of echinocandin resistance in human fungal pathogen Candida albicans. [PDF]

PLoS Pathog, 2021
Sah SK, Hayes JJ, Rustchenko E.
europepmc   +1 more source

Uncovering actionable trade-offs of antifungal resistance in a yeast pathogen

Molecular Systems Biology
The increasing prevalence of antifungal resistance represents a major clinical challenge. To explore potential new therapeutic avenues, we investigated fitness trade-offs associated with azole and echinocandin resistance in Nakaseomyces glabratus (syn ...
Juan Carlos Nunez-Rodriguez, Miquel Àngel Schikora-Tamarit, Toni Gabaldón   +2 more
doaj   +1 more source

A pseudo-outbreak of echinocandin-resistant Candida glabrata: The unreliability of caspofungin testing in predicting echinocandin susceptibility

Journal of the Association of Medical Microbiology and Infectious Disease Canada, 2021
Yahya Shabi, Audra Russell-Tattrie, Amrita Bharat, David Haldane, Glenn Patriquin   +4 more
openaire   +2 more sources

Mitochondrial characteristics of echinocandin tolerance and resistance in Candida glabrata and Candida krusei

Frontiers in Microbiology
BackgroundCandidiasis, especially candidemia, is one of the most common invasive fungal infections. With the increase of risk factors such as tumors, its high incidence and high mortality rate pose a significant challenge to public health. Echinocandins,
Peng Xue, Li Zhang, Li Zhang, Li Zhang, Mingwei Du, Mingwei Du, Mingwei Du, Quan Yuan, Quan Yuan, Quan Yuan, Haiyang He, Haiyang He, Haiyang He, Xiaochun Xue, Wanqing Liao, Wanqing Liao, Wanqing Liao, Yuanyuan Ma, Weihua Pan, Weihua Pan, Weihua Pan, Liuyang Cai, Liuyang Cai, Liuyang Cai   +23 more
doaj   +1 more source

Case Report: Echinocandin-Resistance Candida glabrata FKS Mutants From Patient Following Radical Cystoprostatectomy Due to Muscle-Invasive Bladder Cancer. [PDF]

Front Oncol, 2021
Szymankiewicz M, Kamecki K, Jarzynka S, Koryszewska-Bagińska A, Olędzka G, Nowikiewicz T.   +5 more
europepmc   +1 more source

Mutational landscape and molecular bases of echinocandin resistance in Saccharomyces cerevisiae. [PDF]

Genetics
Durand R, Torbey AG, Giguere M, Pageau A, Dubé AK, Lagüe P, Landry CR.   +6 more
europepmc   +1 more source