Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrata [PDF]
Journal of Fungi, 2018 Candida glabrata has thoroughly adapted to successfully colonize human mucosal membranes and survive in vivo pressures. prior to and during antifungal treatment. Out of all the medically relevant Candida species, C.
Kelley R. Healey, David S. Perlin
doaj +3 more sources
Echinocandin resistance: an emerging clinical problem? [PDF]
Curr Opin Infect Dis, 2014 Echinocandin resistance in Candida is a great concern, as the echinocandin drugs are recommended as first-line therapy for patients with invasive candidiasis. Here, we review recent advances in our understanding of the epidemiology, underlying mechanisms, methods for detection and clinical implications.Echinocandin resistance has emerged over the ...
Arendrup MC, Perlin DS.
europepmc +4 more sources
Understanding Echinocandin Resistance in the Emerging Pathogen Candida auris. [PDF]
Antimicrob Agents Chemother, 2018 ABSTRACT Candida auris has simultaneously emerged on five continents as a fungal pathogen causing nosocomial outbreaks. The challenges in the treatment of C. auris infections are the variable antifungal susceptibility profiles among clinical isolates and the development of resistance to single ...
Kordalewska M +6 more
europepmc +4 more sources
Pan-Echinocandin Resistant C. parapsilosis Harboring an F652S Fks1 Alteration in a Patient with Prolonged Echinocandin Therapy [PDF]
Journal of Fungi, 2022 The isolation of a pan-echinocandin-resistant Candida parapsilosis strain (anidulafungin, caspofungin, micafungin and rezafungin EUCAST MICs > 8 mg/L) from urine of a patient following prolonged exposure to echinocandins (38 days of micafungin followed ...
Maria Siopi +12 more
doaj +5 more sources
KAJIAN MOLEKULER RESISTENSI Candida albicans TERHADAP ANTIFUNGI [PDF]
Jurnal Farmasi Sains dan Komunitas, 2014 : Candida albicans is one of the species Candida which mostly cause infection in human. Antifungal agent azole, polyene, echinocandin, and flucytosine are commonly used for Candida albicans infection treatment.
Damiana Sapta Candrasari
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Echinocandin Resistance in Candida Species Isolates from Liver Transplant Recipients [PDF]
Antimicrobial Agents and Chemotherapy, 2017 ABSTRACT Liver transplant recipients are at risk of invasive fungal infections, especially candidiasis. Echinocandin is recommended as prophylactic treatment but is increasingly associated with resistance. Our aim was to assess echinocandin drug resistance in Candida spp.
Prigent, Gwénolé +10 more
openaire +5 more sources
Echinocandin Resistance in Two Candida haemulonii Isolates from Pediatric Patients [PDF]
Journal of Clinical Microbiology, 2012 We report 3 cases of patients with Candida haemulonii isolates that were obtained from hemocultures. in 2 of the 3 cases, isolates exhibited resistance to echinocandins and fluconazole.
Azevedo Melo, Analy Salles de +4 more
core +4 more sources
Medical Mycology Case Reports, 2016 Mixed fungal infection and acquired echinocandin resistance of Candida spp. remain infrequent. In this study we have reported the case of a patient hospitalized for tuberculosis who experienced multiple infections due to three common Candida species (C ...
Marine Grosset +4 more
doaj +3 more sources
Stress-Induced Changes in the Lipid Microenvironment of β-(1,3)-
mBio, 2019 Aspergillus fumigatus is a leading cause of invasive fungal infections. Resistance to first-line triazole antifungals has led to therapy with echinocandin drugs. Recently, we identified several high-minimum-effective-concentration (MEC) A.
Shruthi Satish +10 more
doaj +2 more sources
Prevalence of Antifungal Resistance, Genetic Basis of Acquired Azole and Echinocandin Resistance, and Genotyping of Candida krusei Recovered from an International Collection. [PDF]
Antimicrob Agents Chemother, 2022 Khalifa HO +6 more
europepmc +2 more sources