Results 51 to 60 of about 2,198,221 (190)
Microbial Cell, 2022 The emergence of drug resistance significantly hampers the treatment of human infections, including those caused by fungal pathogens such as Candida species.
Pedro Pais +4 more
doaj +1 more source
Echinocandin resistance in \(Candida\) \(glabrata\)
, 2022 Candida glabrata ist die zweithäufigste Ursache von Candidämien und invasiven Hefepilzinfektionen in Europa. Im Gegensatz zu C. albicans zeigt C.
Aldejohann, Alexander Maximilian
core +1 more source
Azole-Resistant Aspergillus and Echinocandin-Resistant Candida: What Are the Treatment Options?
Current Fungal Infection Reports, 2020 This review summarizes current treatment options for echinocandin-resistant Candida spp. (ERC) and azole-resistant Aspergillus fumigatus (ARAF), emphasizing recent in vitro/in vivo data, clinical reports, and consensus statements.Advances in ERC and ARAF treatment are limited to specific antifungal combinations and dose optimization but remain reliant ...
Alison R. Novak +3 more
openaire +3 more sources
Clinical perspectives on echinocandin resistance among Candida species [PDF]
Current Opinion in Infectious Diseases, 2015 We review and offer our clinical perspectives on the emergence of echinocandin-resistant Candida.Candida FKS gene mutations attenuate echinocandin activity, but overall mutation rates among clinical isolates remain low (Candida glabrata, ∼4%; other species,
Ryan K, Shields +2 more
openaire +2 more sources
Fungal biofilm resistance [PDF]
, 2012 Fungal biofilm infections have become increasingly recognised as a significant clinical problem. One of the major reasons behind this is the impact that these have upon treatment, as antifungal therapy often fails and surgical intervention is required ...
Ramage, Gordon +7 more
core +1 more source
Acquired resistance to echinocandins in Candida albicans: case report and review [PDF]
Journal of Antimicrobial Chemotherapy, 2007 A patient with Candida albicans thrush and oesophagitis was treated with high doses of caspofungin but treatment eventually failed. Four C. albicans isolates were serially recovered before and after caspofungin treatment. A microbiological study was performed to characterize these four isolates.In vitro antifungal susceptibility testing was performed ...
Baixench, Marie-Thérèse +7 more
openaire +4 more sources
Journal of Fungi, 2023 Invasive fungal infections (IFIs) are frequent and outcome-relevant complications in the early postoperative period after orthotopic liver transplantation (OLT).
Robert Breitkopf +4 more
doaj +1 more source
The Mechanisms of Resistance to Echinocandin Class of Antifungal Drugs
Nippon Ishinkin Gakkai Zasshi, 2009 The echinocandin (candin) class of antifungal drugs inhibit beta-1,3-glucan synthase and block synthesis of beta-1,3-glucan , an important polysaccharide in fungal cell walls. Candins are used widely for treatment of systemic infections caused by Candida and Aspergillus because of their high potency and low toxicity to humans.
Niimi, Kyoko, Niimi, Masakazu
openaire +3 more sources
Echinocandin-resistant Candida tropicalis Bloodstream Infections [PDF]
Open Forum Infectious Diseases, 2017 BACKGROUND: The aim of this study is to describe the clinical manifestations, molecular mechanisms, and treatment outcomes of patients with echinocandin-resistant Candida tropicalis (C. tropicalis) bloodstream infections (BSI). METHODS: A PubMed search was conducted using the search terms related to C. tropicalis BSI and echinocandin resistance.
Sfeir, Maroun +10 more
openaire +1 more source
Australian Veterinary Journal, EarlyView.A 3‐year‐old male Border Collie diagnosed with immune‐mediated dermatopathy, managed with tapering prednisolone and cyclosporine, developed rapidly progressive ocular signs and additional cutaneous lesions. Histopathology, mycological culture, polymerase chain reaction and sequencing confirmed intraocular and cutaneous infection due to Curvularia ...
T Brasil‐Ervedosa +4 more
wiley +1 more source