Results 51 to 60 of about 12,521 (204)

Candida auris, what do paediatricians need to know? [PDF]

open access: yes, 2018
AW is supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of Aberdeen.Peer reviewedPublisher ...
Warris, Adilia
core   +1 more source

Abdominal Candidiasis Is a Hidden Reservoir of Echinocandin Resistance [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2014
ABSTRACT FKS mutant Candida isolates were recovered from 24% (6/25) of abdominal candidiasis patients exposed to echinocandin. Candida glabrata (29%) and Candida albicans (14%) mutants were identified.
Ryan K, Shields   +3 more
openaire   +2 more sources

Multiple genome analysis of Candida glabrata clinical isolates renders new insights into genetic diversity and drug resistance determinants

open access: yesMicrobial Cell, 2022
The emergence of drug resistance significantly hampers the treatment of human infections, including those caused by fungal pathogens such as Candida species.
Pedro Pais   +4 more
doaj   +1 more source

Combined antifungal resistance and biofilm tolerance: the global threat of Candida auris [PDF]

open access: yes, 2019
The enigmatic yeast Candida auris has emerged over the last decade and rapidly penetrated our consciousness. The global threat from this multidrug-resistant yeast has generated a call to arms from within the medical mycology community.
Kean, Ryan, Ramage, Gordon
core   +2 more sources

Titan cell production in Cryptococcus neoformans reshapes the cell wall and capsule composition during infection [PDF]

open access: yes, 2018
This work was supported by the National Institutes of Health (R01AI080275 and R21AI22352), the NIH Fogarty International Center (R25TW009345), the University of Minnesota Center for Translational Science Institute (UL1TR000114), Wellcome Trust (086827 ...
Gow, Neil A R   +5 more
core   +1 more source

Gaining insights from Candida biofilm heterogeneity: one size does not fit all [PDF]

open access: yes, 2018
Despite their clinical significance and substantial human health burden, fungal infections remain relatively under-appreciated. The widespread overuse of antibiotics and the increasing requirement for indwelling medical devices provides an opportunistic ...
Delaney, Christopher   +8 more
core   +7 more sources

Potential Use of MALDI-ToF Mass Spectrometry for Rapid Detection of Antifungal Resistance in the Human Pathogen Candida glabrata. [PDF]

open access: yes, 2017
The echinocandins are relatively new antifungal drugs that represent, together with the older azoles, the recommended and/or preferred agents to treat candidaemia and other forms of invasive candidiasis in human patients.
De Carolis, E.   +6 more
core   +2 more sources

Evolutionary accumulation of FKS1 mutations from clinical echinocandin-resistant Candida auris

open access: yesEmerging Microbes and Infections
Introduction: Drug resistance to echinocandins, first-line drugs used to treat Candida auris infection, is rapidly emerging. However, the accumulation of mutations in genes other than FKS1 (before an isolate develops to resistance via FKS1 mutations ...
Sufei Tian   +8 more
doaj   +1 more source

Invasive Fungal Breakthrough Infections under Targeted Echinocandin Prophylaxis in High-Risk Liver Transplant Recipients

open access: yesJournal of Fungi, 2023
Invasive fungal infections (IFIs) are frequent and outcome-relevant complications in the early postoperative period after orthotopic liver transplantation (OLT).
Robert Breitkopf   +4 more
doaj   +1 more source

Resistance in Candida albicans: exploring the cell wall barrier by proteomics [PDF]

open access: yes, 2015
The incidence of candidiasis has dramatically increased and bloodstream infections due to different species of Candida are becoming a prime cause of morbidity and mortality in different types of immunocompromised patients.
Angiolella, Letizia   +2 more
core   +1 more source

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