Results 61 to 70 of about 12,521 (204)
First report on echinocandin resistant Polish Candida isolates
Acta Biochimica Polonica, 2019 Purpose: Candida spp. are ranked as one of the four major causative agents of fungal infections. The number of infections caused by Candida species resistant to fluconazole, which is applied as the first line drug in candidiasis treatment, increases every year. In such cases the application of echinocandin is necessary.
Martyna Mroczyńska +1 more
openaire +3 more sources
Azole-Resistant Aspergillus and Echinocandin-Resistant Candida: What Are the Treatment Options?
Current Fungal Infection Reports, 2020 This review summarizes current treatment options for echinocandin-resistant Candida spp. (ERC) and azole-resistant Aspergillus fumigatus (ARAF), emphasizing recent in vitro/in vivo data, clinical reports, and consensus statements.Advances in ERC and ARAF treatment are limited to specific antifungal combinations and dose optimization but remain reliant ...
Alison R. Novak +3 more
openaire +3 more sources
Development of Echinocandin Resistance in Clavispora lusitaniae during Caspofungin Treatment [PDF]
Journal of Clinical Microbiology, 2011 ABSTRACT Clavispora lusitaniae is an opportunistic human pathogen responsible for 0.6 to 2% of candidemia. This species is intrinsically susceptible to echinocandins. Nevertheless, in this study, development of echinocandin resistance in C.
Desnos-Ollivier, Marie +4 more
openaire +3 more sources
Journal of Fungi, 2020 Invasive infections caused by the opportunistic pathogen Candida glabrata are treated with echinocandin antifungals that target β-1,3-glucan synthase, an enzyme critical for fungal cell wall biosynthesis. Echinocandin resistance develops upon mutation of
Kelley R. Healey +7 more
doaj +1 more source
Antimicrobial Activities and Mechanisms of Magnesium Oxide Nanoparticles (nMgO) against Pathogenic Bacteria, Yeasts, and Biofilms. [PDF]
, 2018 Magnesium oxide nanoparticle (nMgO) is a light metal based antimicrobial nanoparticle that can be metabolized and fully resorbed in the body. To take advantage of the antimicrobial properties of nMgO for medical use, it is necessary to determine the ...
Grelling, Nathaniel +4 more
core +3 more sources
New cell wall-affecting antifungal antibiotics [PDF]
, 2013 Capítulo 9.Fungi have emerged worldwide as increasingly frequent causes of healthcare-associated infections. Invasive fungal infections can be life-threatening.
Cortés, Juan Carlos G. +2 more
core +2 more sources
Advanced Science, EarlyView.We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai +8 more
wiley +1 more source
Microorganisms, 2023 Introduction: Surveillance of Candida species isolates from blood cultures (BCs) in Europe is considered fragmented, unable to allow the definition of targets of antifungal stewardship recommendations especially during the SARS-CoV-2 pandemic.
Matteo Boattini +18 more
doaj +1 more source
Sentinel Case of Candida auris in the Western United States Following Prolonged Occult Colonization in a Returned Traveler from India. [PDF]
, 2019 Candida auris is an emerging multidrug-resistant yeast with high mortality. We report the sentinel C. auris case on the United States West Coast in a patient who relocated from India.
Crawford, Emily D +12 more
core +1 more source
Rapid Development of Candida krusei Echinocandin Resistance during Caspofungin Therapy [PDF]
Antimicrobial Agents and Chemotherapy, 2015 ABSTRACT In invasive candidiasis, there has been an epidemiological shift from Candida albicans to non- albicans species infections, including infections with C. glabrata , C. parapsilosis , C. tropicalis , and
A, Forastiero +8 more
openaire +2 more sources