Results 111 to 120 of about 21,210 (293)
Mycoses, Volume 68, Issue 6, June 2025.ABSTRACT Background Invasive fungal diseases (IFD) pose significant challenges in paediatric oncology. Their management is complicated by limited paediatric‐specific evidence, lack of standardised protocols and variability in resources across centres.
Danila Seidel +68 more
wiley +1 more source
Infection and Drug Resistance, 2018 Candida species remains one of the most important causes of opportunistic infections worldwide. Invasive candidiasis (IC) is associated with considerable morbidity and mortality in liver disease (LD) patients if not treated promptly.
S. F. Yeoh +5 more
semanticscholar +1 more source
Lienhwalides: Unique Tropolone–Maleidride Hybrids from Hypoxylon lienhwacheense
ChemBioChem, Volume 26, Issue 10, May 27, 2025.Lienhwalides are novel tropolone–maleidride hybrid molecules unique in nature. Absolute configuration is solved by semisynthetic approaches and X‐ray analysis. Interplay between both lwt and lwm biosynthetic gene clusters is responsible for the production of lienhwalides.
Katharina Schmidt +13 more
wiley +1 more source
Cell Reports, 2018 Summary: Candida albicans is a leading cause of death due to fungal infection. Treatment of systemic candidiasis often relies on echinocandins, which disrupt cell wall synthesis. Resistance is readily acquired via mutations in the drug target gene, FKS1.
Tavia Caplan +6 more
doaj
In pursuit of the ideal antifungal agent for Candida infections: high-throughput screening of small molecules [PDF]
, 2014 Candida infections have created a great burden on the public healthcare sector. The situation is worsened by recent epidemiological changes. Furthermore, the current arsenal of antifungal agents is limited and associated with undesirable drawbacks ...
Samaranayake, Lakshman P. +2 more
core +1 more source
Characterization of COVID‐19‐Associated Candidemia Among Burn Patients
Journal of Clinical Laboratory Analysis, Volume 39, Issue 10, May 2025.This study investigates the distribution of Candida species isolated from burn patients with candidemia, colonization, and urinary cultures. The findings highlight the predominance of C. albicans and C. parapsilosis across different sample types, including wound colonization, blood, and urine.
Maryam Salimi +12 more
wiley +1 more source
Frontiers in Microbiology, 2019 The pathogenic yeast Candida glabrata has become a public health issue due to the increasing number of echinocandin resistant clinical strains reported.
Olga Rivero-Menendez +12 more
doaj +1 more source
Performance Evaluation of Five Real‐Time PCR Assays for the Detection of Candida auris DNA
Mycoses, Volume 68, Issue 5, May 2025.ABSTRACT Objectives This study aimed to systematically evaluate and compare the performance of two laboratory‐developed assays (LDAs) and three commercially available real‐time PCR assays for the detection of Candida auris. The analytical sensitivity, specificity and limit of detection (LOD) of each assay were assessed, alongside their clinical ...
Jochem B. Buil +8 more
wiley +1 more source
Prognostic factors and historical trends in the epidemiology of candidemia in critically ill patients: an analysis of five multicenter studies sequentially conducted over a 9-year period [PDF]
, 2014 To describe temporal trends in the epidemiology, clinical management and outcome of candidemia in intensive care unit (ICU) patients.This study was a retrospective analysis of 1,392 episodes of candidemia in 647 adult ICU patients from 22 Brazilian ...
Andreotti, Ricardo +7 more
core +1 more source