Results 11 to 20 of about 17,763 (261)
Fungal echinocandin resistance [PDF]
F1000 Biology Reports, 2010 Echinocandins are the most recent introduction to the antifungal armamentarium and target the synthesis of β-(1,3)-glucan, the major structural polysaccharide of the fungal cell wall. Mechanisms have been identified that reduce the efficacy of the echinocandins: mutations of the Fks subunit of the target enzyme complex or a compensatory increase in the
Carol A. Munro
+6 more sources
The Importance of Early Mycological Clearance of Uncomplicated Candidaemia and Its Implications for Clinical Practice. [PDF]
MycosesABSTRACT Invasive candidiasis is a life‐threatening infection associated with high morbidity, mortality and healthcare costs in both general and critical care settings. Timely diagnosis and adequate antifungal treatment are essential to improving patient outcomes and limiting unnecessary use of healthcare resources.
Cornely OA +7 more
europepmc +2 more sources
Journal of Fungi, 2021 Candiduria is a common nosocomial infection in hospitalized patients, which may progress into life-threatening candidemia. Successful treatment of urosepsis requires early and effective antifungal therapy, while the available agents within three ...
Zuzana Javorova Rihova +2 more
doaj +1 more source
Review on Current Status of Echinocandins Use
Antibiotics, 2020 Fungal infections are rising all over the world every year. There are only five medical compound classes for treatment: triazoles, echinocandins, polyenes, flucytosine and allylamine.
Martyna Mroczyńska +1 more
doaj +1 more source
BMC Infectious Diseases, 2017 Background Cost-effectiveness studies of echinocandins for the treatment of invasive candidiasis, including candidemia, are rare in Asia. No study has determined whether echinocandins are cost-effective for both Candida albicans and non-albicans Candida ...
Huang-Tz Ou +3 more
doaj +1 more source
Journal of Fungi, 2020 Candida haemulonii complex (C. haemulonii, C. duobushaemulonii and C. haemulonii var. vulnera) is well-known for its resistance profile to different available antifungal drugs.
Lívia S. Ramos +3 more
doaj +1 more source
Quantitative Analysis of Candida Cell Wall Components by Flow Cytometrywith Triple-Fluorescence Staining [PDF]
, 2017 This work was supported by the European Commission within the FP7 Framework Programme [Fungitect-Grant No 602125]. We also thank Thomas Sauer, Vienna Biocenter Campus (VBC), Austria, for technical support at the FACS facility of the MFPL, Karl Kuchler ...
Gow, N +5 more
core +1 more source
Role of Antifungal Combinations in Difficult to Treat Candida Infections
Journal of Fungi, 2021 Candida infections are varied and, depending on the immune status of the patient, a life-threatening form may develop. C. albicans is the most prevalent species isolated, however, a significant shift towards other Candida species has been noted ...
Roxana G. Vitale
doaj +1 more source
New strategic insights into managing fungal biofilms [PDF]
, 2015 Fungal infections have dramatically increased in the last decades in parallel with an increase of populations with impaired immunity, resulting from medical conditions such as cancer, transplantation or other chronic diseases.
Borghi, Elisa +6 more
core +16 more sources
Successful management of recalcitrant fungal keratitis with topical caspofungin
GMS Ophthalmology Cases, 2022 Objective: To report a case of recalcitrant fungal keratitis successfully managed with topical caspofungin acetate in North India.Methods: Case report and literature review.Results: An 18-year-old male patient presented with complaints of redness ...
Goel, Siddhi +2 more
doaj +1 more source