Results 61 to 70 of about 17,763 (261)

The Fungal Cell Wall : Structure, Biosynthesis, and Function [PDF]

open access: yes, 2017
N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M.
Aimanianda   +215 more
core   +1 more source

Host Transcriptomics and Culture‐Independent Testing for the Management of Febrile Neutropenia: Data From an Observational Study Conducted in a Bone Marrow Transplant Unit

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background Managing febrile neutropenia is challenging due to the limited sensitivity of blood culture (BC) and the lack of tools differentiating infectious from non‐infectious fever. T2 magnetic resonance (T2MR) is a culture‐independent system detecting bacteria (T2Bacteria) and yeasts (T2Candida); SeptiCyte RAPID is a host response assay ...
Anna Maria Peri   +6 more
wiley   +1 more source

Two Sequential Clinical Isolates of Candida glabrata with Multidrug-Resistance to Posaconazole and Echinocandins

open access: yesAntibiotics, 2021
Candida glabrata is one of the most prevalent causative pathogens of invasive candidiasis, and multidrug-resistant strains are emerging. We identified two clinical isolates of C. glabrata, BMU10720 and BMU10722 sequentially isolated from one patient with
Qiqi Wang   +9 more
doaj   +1 more source

Microfluidic live‐cell imaging of Aspergillus fumigatus and Candida albicans hyphal growth treated with AmBisome and Caspofungin

open access: yesJournal of Microscopy, EarlyView.
Abstract Hyphal forms of human pathogenic fungi cause invasive disease in humans, but the hyphal response to antifungals is understudied. In the major fungal pathogens Aspergillus fumigatus and Candida albicans, we used microfluidic‐coupled, fluorescence‐mediated live‐cell imaging to capture the real‐time responses of fungal hyphae to clinical ...
D. D. Thomson   +3 more
wiley   +1 more source

Can Intravenous Antifungal therapy be safely used in the Outpatient Parenteral Antimicrobial Therapy (OPAT) setting? [PDF]

open access: yes, 2019
Outpatient parenteral antimicrobial therapy (OPAT) is an established treatment option for patients with a variety of infections who require a period of intravenous therapy, are clinically stable, and do not require continuous monitoring.
Kenny, Claire   +2 more
core   +2 more sources

Micafungin: a sulfated echinocandin [PDF]

open access: yesThe Journal of Antibiotics, 2009
Micafungin is the second approved antifungal agent in the echinocandin series and is now used worldwide in chemotherapy for life-threatening fungal infections. It is water-soluble and is semi-synthesized from the acylated cyclic hexapeptide FR901379, a natural product from the fungus Coleophoma empetri F-11899, through enzymatic deacylation of FR901379,
openaire   +2 more sources

Treatment of Aspergillosis. [PDF]

open access: yes, 2018
Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
core   +1 more source

Candida auris in Heart Transplant Donor: First Isolation in a Southern Italy Heart Transplant Center

open access: yesClinical Case Reports, Volume 14, Issue 1, January 2026.
Timeline of infection control in a heart transplant from a donor colonized with Candida auris: from detection at retrieval to strict isolation, antifungal prophylaxis, negative follow‐up cultures, and successful prevention of transmission. ABSTRACT Candida auris is an emerging multidrug‐resistant fungal pathogen increasingly implicated in healthcare ...
Lorenzo Giovannico   +6 more
wiley   +1 more source

Echinocandin Resistance in Candida [PDF]

open access: yesClinical Infectious Diseases, 2015
Invasive fungal infections are an important infection concern for patients with underlying immunosuppression. Antifungal therapy is a critical component of patient care, but therapeutic choices are limited due to few drug classes. Antifungal resistance, especially among Candida species, aggravates the problem.
openaire   +2 more sources

Imidazolium‐Based Ionic Liquids as Antifungal and Antibiofilm Agents Against Candida tropicalis

open access: yesChemistrySelect, Volume 11, Issue 4, 28 January 2026.
Candida sp. biofilms, particularly those formed on catheters, represent a major clinical challenge. This study evaluates ionic liquids using an experimental biofilm model, demonstrating significant antifungal activity and biofilm disruption, supporting their potential application as alternative strategies for device‐associated infection control ...
Giovanna de Jesus Agostinetto   +4 more
wiley   +1 more source

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