Results 81 to 90 of about 21,836 (300)

Fungal biofilm resistance [PDF]

open access: yes, 2012
Fungal biofilm infections have become increasingly recognised as a significant clinical problem. One of the major reasons behind this is the impact that these have upon treatment, as antifungal therapy often fails and surgical intervention is required ...
Rajendran, Ranjith   +3 more
core   +4 more sources

Treatment of invasive candidiasis with echinocandins [PDF]

open access: yesMycoses, 2009
SummaryBlood stream infections by Candida spp. represent the majority of invasive fungal infections in intensive care patients. The high crude mortality of invasive candidiasis remained essentially unchanged during the last two decades despite new treatment options that became available.
Angela Steinbach   +3 more
openaire   +3 more sources

The Fungal Cell Wall : Structure, Biosynthesis, and Function [PDF]

open access: yes, 2017
N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M.
Aimanianda   +215 more
core   +1 more source

Solid‐State NMR Reveals Reorganization of the Aspergillus fumigatus Cell Wall Due to a Host‐Defence Peptide

open access: yesAngewandte Chemie, Volume 137, Issue 35, August 25, 2025.
Understanding the mode of action is critical to develop new antifungal drugs. Solid‐state NMR was used to study the reorganization of the Aspergillus fumigatus cell wall by a host‐defence peptide. We identified specific polysaccharides and amino acids that are affected by the peptide.
Ajit Kumar Bishoyi   +5 more
wiley   +2 more sources

Treatment of Aspergillosis. [PDF]

open access: yes, 2018
Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
core   +1 more source

Successful Treatment of Refractory Candida auris Ventriculitis With Intraventricular Liposomal Amphotericin B

open access: yesClinical Case Reports, Volume 13, Issue 9, September 2025.
ABSTRACT We report on a case of a patient in their early 60's with a history of traumatic brain injury, decompressive cranioplasty, and chronic ventriculoperitoneal (VP) shunt who presented from a nursing home with altered mental status and status epilepticus.
Christine A. Vu   +2 more
wiley   +1 more source

Resistance in Candida albicans: exploring the cell wall barrier by proteomics [PDF]

open access: yes, 2015
The incidence of candidiasis has dramatically increased and bloodstream infections due to different species of Candida are becoming a prime cause of morbidity and mortality in different types of immunocompromised patients.
Angiolella, Letizia   +2 more
core   +1 more source

An Overview of Recent Possibilities in Pharmacotherapy of Diseases of the Oral Mucosa, Salivary Glands, and Periodontal Tissue

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2013
Introduction: A review of newer drugs for topical or systemic administration useful in contemporary dentistry in the therapy of diseases of periodontal tissue, oral mucous membrane, and salivary glands available in Czech Republic was given in this ...
R. Slezák   +6 more
doaj   +1 more source

Real World Incidence and Etiology of Infectious Complications in Adults With Ph‐Negative Acute Lymphoblastic Leukemia Treated With the Pediatric‐Inspired GIMEMA LAL1913 Program. A Campus All Study

open access: yesHematological Oncology, Volume 43, Issue 5, September 2025.
ABSTRACT Infections often complicate pediatric‐inspired treatments for adult Philadelphia‐negative acute lymphoblastic leukemia (Ph‐ ALL). Literature data on these complications are difficult to interpret due to the heterogeneity of types of infections analyzed or patients and treatment characteristics.
Patrizia Zappasodi   +27 more
wiley   +1 more source

APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis. [PDF]

open access: yes, 2019
Invasive pulmonary aspergillosis (IPA) due to Aspergillus fumigatus is a serious fungal infection in the immunosuppressed patient population. Despite the introduction of new antifungal agents, mortality rates remain high, and new treatments are needed ...
Alkhazraji, Sondus   +7 more
core  

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