Results 81 to 90 of about 21,210 (293)
ChemistryOpen, EarlyView.A series of azomethine‐pyrazole derivatives bearing a para‐substituted azo‐phenyl ring is straightforwardly prepared. The new compounds display an elevated antifungal activity against various Candida species and Cryptococcus neoformans strains. DFT and molecular docking calculations are used to determine possible routes of action through interactions ...
María Isabel Murillo +8 more
wiley +1 more source
Metabolites, 2020 We reviewed the licensed antifungal drugs and summarized their mechanisms of action, pharmacological profiles, and susceptibility to specific fungi. Approved antimycotics inhibit 1,3-β-d-glucan synthase, lanosterol 14-α-demethylase, protein ...
Jiří Houšť +2 more
doaj +1 more source
Emerging Threats in Antifungal-Resistant Fungal Pathogens. [PDF]
, 2016 The use of antifungal drugs in the therapy of fungal diseases can lead to the development of antifungal resistance. Resistance has been described for virtually all antifungal agents in diverse pathogens, including Candida and Aspergillus species.
Sanglard, D.
core +2 more sources
Sentinel Case of Candida auris in the Western United States Following Prolonged Occult Colonization in a Returned Traveler from India. [PDF]
, 2019 Candida auris is an emerging multidrug-resistant yeast with high mortality. We report the sentinel C. auris case on the United States West Coast in a patient who relocated from India.
Crawford, Emily D +12 more
core +1 more source
Mycoses, Volume 68, Issue 7, July 2025.ABSTRACT Background Candida (Candidozyma) auris has distinct genetic clades. Clade distinction is relevant for infection control and epidemiological purposes. State‐of‐the‐art typing methodologies for clade distinction are based on genomic approaches, such as short tandem repeat (STR) analysis and whole‐genome sequencing (WGS).
Camylla C. de Melo +13 more
wiley +1 more source
Treatment of invasive candidiasis with echinocandins [PDF]
Mycoses, 2009 SummaryBlood stream infections by Candida spp. represent the majority of invasive fungal infections in intensive care patients. The high crude mortality of invasive candidiasis remained essentially unchanged during the last two decades despite new treatment options that became available.
Angela Steinbach +3 more
openaire +3 more sources
Candida glabrata Resistance to Echinocandins Associated with FKS Genes Mutations: How Urgent is the Problem? [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2016 The resistance of the systemic Candida infections causative agents is a cornerstone of the selection of an effective therapy. But if before the problem was limited to resistance to azole antifungals, then by now we have enough data about cases of ...
Veselov A.V.
doaj
ChemBioChem, Volume 26, Issue 12, June 16, 2025.Bioactivity‐guided isolation led to the discovery of a potent and selective inhibitor of the phytopathogen Botrytis cinerea, pleosporacin (1), from mycelia extracts of the fungal strain Pleosporales sp. IBWF 020‐21. The biosynthesis of the nonribosomal cyclic lipodepsipeptide 1 was elucidated via heterologous reconstitution in Aspergillus oryzae ...
Carsten Wieder +6 more
wiley +1 more source
Česká Stomatologie a Praktické Zubní Lékařství, 2013 Introduction: A review of newer drugs for topical or systemic administration useful in contemporary dentistry in the therapy of diseases of periodontal tissue, oral mucous membrane, and salivary glands available in Czech Republic was given in this ...
R. Slezák +6 more
doaj +1 more source
The Fungal Cell Wall : Structure, Biosynthesis, and Function [PDF]
, 2017 N.G. is funded by the Wellcome Trust via a senior investigator award and a strategic award and by the MRC Centre for Medical Mycology. C.M. acknowledges the support of the Wellcome Trust and the MRC. N.G. and C.M.
Aimanianda +215 more
core +1 more source