Results 61 to 70 of about 730 (160)

The Immune Response of Acanthaster planci to Oxbile Injections and Antibiotic Treatment

Journal of Marine Sciences, Volume 2014, Issue 1, 2014., 2014
Bile salts have been recently identified as a rapid and effective method for killing A. planci. However the mechanistic basis of this new control method is poorly understood. This study explored the immune response(s) of A. planci and/or pathogenesis resulting from the injection of bile salts. To account for the possible role of pathogenesis in causing
Alexandra Grand, Morgan Pratchett, Jairo Rivera-Posada, Norman Ying Shiu Woo   +3 more
wiley   +1 more source

Expression of Pigment Cell‐Specific Genes in the Ontogenesis of the Sea Urchin Strongylocentrotus intermedius

Evidence-Based Complementary and Alternative Medicine, Volume 2011, Issue 1, 2011., 2011
One of the polyketide compounds, the naphthoquinone pigment echinochrome, is synthesized in sea urchin pigment cells. We analyzed polyketide synthase (pks) and sulfotransferase (sult) gene expression in embryos and larvae of the sea urchin Strongylocentrotus intermedius from various stages of development and in specific tissues of the adults.
Natalya V. Ageenko, Konstantin V. Kiselev, Nelly A. Odintsova   +2 more
wiley   +1 more source

Synthesis of Polyhydroxylated Aminonaphthazarins Related to Natural Pigments

Natural Product Communications, 2018
Amino analogs of echinochrome and ethylmompain, metabolites of sea urchins Scaphechinus mirabilis and Echinothrix diadema , and amino analogs of cristazarin, a metabolite of lichen Cladonia cristatella , were synthesized.
Galina I. Melman, Natalia D. Pokhilo, Lyubov N. Atopkina, Vladimir A. Denisenko, Victor Ph. Anufriev   +4 more
doaj   +1 more source

Liposomal Form of the Echinochrome-Carrageenan Complex

Marine Drugs, 2018
Inclusion of drugs in liposomes offers the potential for localized and sustained delivery to mucosal surfaces. The inclusion of the carrageenan matrix with echinochrome A ((Ech)—the active substance of the drug Histochrome) in liposomes was studied.
Irina M. Yermak, Vladimir I. Gorbach, Valery P. Glazunov, Anna O. Kravchenko, Natalya P. Mishchenko, Evgeniya A. Pimenova, Viktoria N. Davydova   +6 more
doaj   +1 more source

Free Radical Scavenging Activities of Naturally Occurring and Synthetic Analogues of Sea Urchin Naphthazarin Pigments

Natural Product Communications, 2012
Antioxidant activities of minor pigments of sea urchins ( 1–5 ) and synthetic naphthazarins ( 7–13 ) were evaluated and compared with echinochrome A ( 6 ) using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azinobis(3-ethylbenzothiazoline-6-sulfonate ...
Natalia K. Utkina, Natalia D. Pokhilo
doaj   +1 more source

Regulatory role of Echinochrome A in cancer-associated fibroblast-mediated lung cancer cell migration. [PDF]

Toxicol Res
Echinochrome A (Ech A), a marine biosubstance isolated from sea urchins, is a strong antioxidant, and its clinical form, histochrome, is being used to treat several diseases, such as ophthalmic, cardiovascular, and metabolic diseases. Cancer-associated fibroblasts (CAFs) are a component of the tumor stroma and induce phenotypes related to tumor ...
Eum DY, Lee C, Tran CS, Lee J, Park SY, Jeong MS, Jin Y, Shim JW, Lee SR, Koh M, Vasileva EA, Mishchenko NP, Park SJ, Choi SH, Choi YJ, Yun H, Heo K.   +16 more
europepmc   +3 more sources

Atypical Protein Kinase Cs in Melanoma Progression [PDF]

, 2019
Melanoma is one of the fastest growing types of cancer worldwide in terms of incidence. To date, reports show over 92,000 new cases in the United States in 2018. Previously, we introduced protein kinase C-iota (PKC-ι) as an oncogene in melanoma.
Acevedo-Duncan, Mildred, Apostolatos, Christopher A., Ratnayake, Wishrawana S.   +2 more
core   +2 more sources

Metabolomic Profiles on Antiblastic Cardiotoxicity: New Perspectives for Early Diagnosis and Cardioprotection [PDF]

, 2022
Antiblastic drugs-induced cardiomyopathy remains a relevant cause of morbidity and mortality, during and after chemotherapy, despite the progression in protective therapy against cardiovascular diseases and myocardial function.
Cadeddu Dessalvi, Christian, Caggiari, Ludovica, Deidda, Martino, Fazzini, Luca, Mercuro, Giuseppe, Onnis, Carlotta, Saba, Luca   +6 more
core   +2 more sources

Electrocardiographic manifestation of cardiac repolarization dispersion [PDF]

, 2019
Alterations of repolarization heterogeneity in the heart have been established as anAlterations of repolarization heterogeneity in the heart have been established as ...
Sedova Ksenia
core  

Innovative Applications of Marine Macroalgae Polysaccharides in Tissue Engineering and Drug Delivery: A Review Study

Health Science Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Aims Marine macroalgae are abundant sources of bioactive polysaccharides—including alginate, fucoidan, ulvan, carrageenan, and agarose—widely recognized for extensive biomedical applications. These polysaccharides exhibit remarkable biological properties, such as immunostimulatory, anticancer, antioxidant, antimicrobial, and ...
Foroozan Jalalibidgoli, Pardis Irankhahi, Helia Hajihassani, Ali Akbar Ghotbi‐Ravandi   +3 more
wiley   +1 more source