Sea urchins are basal deuterostomes that share key molecular components of innate immunity with humans, and are a powerful model for the study of innate immunity. Here we characterize the morphology and associated molecular markers of immune cell types in a newly developed model sea urchin, Lytechinus pictus.
Katherine T Nesbit +8 more
wiley +1 more source
Pigment Cell Differentiation in Sea Urchin Blastula-Derived Primary Cell Cultures
The quinone pigments of sea urchins, specifically echinochrome and spinochromes, are known for their effective antioxidant, antibacterial, antifungal, and antitumor activities. We developed in vitro technology for inducing pigment differentiation in cell
Natalya V. Ageenko +3 more
doaj +1 more source
Echinochrome A Release by Red Spherule Cells Is an Iron-Withholding Strategy of Sea Urchin Innate Immunity [PDF]
Cellular immune defences in sea urchins are shared amongst the coelomocytes – a heterogeneous population of cells residing in the coelomic fluid (blood equivalent) and tissues. The most iconic coelomocyte morphotype is the red spherule cell (or amebocyte)
Betts, Joshua +3 more
core +2 more sources
SUPRESSION OF MICROSOMAL OXIDATION WEAKENS HISTOCHROME’S DIURETIC EFFECT AT RATS
Histochrome is the medicinal form of echinochrome (2, 3, 5, 6, 8-pentahydroxy-7-ethyl-1,4-naphthoquinone). Arisen during clinical application of the drug questions concerning its biotransformation have predetermined the aim of this research: to study ...
O. S. Talalaeva +5 more
doaj +1 more source
Comparative Raman spectroscopy study of the coelomic fluid of grazing sea urchins and their native seawater: prospect for a potential indicator of environmental aggression [PDF]
Sea urchins have limited ability to move, and they use the watervascular circulation system to pump surrounding sea water in order to set body parts in motion.
F. NEKVAPIL +2 more
core +1 more source
Macromere cell fates during sea urchin development [PDF]
This paper examines the cell lineage relationships and cell fates in embryos of the sea urchin Strongylocentrotus purpuratus leading to the various cell types derived from the definitive vegetal plate territory or the veg_2 tier of cells.
Britten, Roy J. +3 more
core
Antimicrobial peptides in sea urchins. Isolation, characterization and expression [PDF]
Echinoderms are interesting animals for biodiscovery/bioprospecting as sources for novel compounds that have interesting activities. These compounds might be developed into potential drug candidates.
Li, Chun
core +1 more source
Ηλεκτροϊνοποιημένες μικρο-/νανοΐνες ως συστήματα ελεγχόμενης αποδέσμευσης του εχινοχρώματος Α [PDF]
Στα πλαίσια της παρούσας εργασίας πραγματοποιήθηκε απομόνωση της βιοδραστικής κόκκινης χρωστικής εχινόχρωμα Α από αχινούς του γένους Diadema που συλλέχθηκαν από τον κόλπο του Αγίου Γεωργίου στο Καστελλόριζο, σε βάθος 1-5 m, τον Σεπτέμβριο του 2021.
Mavrogiorgis Panagiotis +1 more
core
Antiviral Potential of Sea Urchin Aminated Spinochromes against Herpes Simplex Virus Type 1
Herpes simplex virus type 1 (HSV-1) is one of the most prevalent pathogens worldwide requiring the search for new candidates for the creation of antiherpetic drugs.
Natalia P. Mishchenko +8 more
doaj +1 more source
The echinoderm innate humoral immune response [PDF]
: Multicellular organisms have an immune system, which is essential for the survival of living beings. Interest in the immune system has been expanded since common characteristics of innate immunity between Drosophila melanogaster (Meigen, 1830) and ...
Al-Sharif WZ +14 more
core +1 more source

