Results 71 to 80 of about 114,625,497 (147)

The Teratogenic Mechanism of Echinochrome as a Hypoglycemic Agent on Wistar Rats [PDF]

The Open Biomarkers Journal, 2019
Background: Echinochrome (Ech) is the active ingredient in the Histochrome drug, which possesses strong antioxidant, hypolipidemic and hypoglycemic activity. Objective: The present work aimed to characterize the malformations induced by ...
Ayman S. Mohamed, Eman Y. Salah EL Din, Neveen A. Farag, Abdel Rahman A. Tawfik   +3 more
openaire   +1 more source

Marine Polyhydroxynaphthoquinone, Echinochrome A: Prevention of Atherosclerotic Inflammation and Probable Molecular Targets

, 2020
The effect of low doses of echinochrome A (EchA), a natural polyhydroxy-1,4-naphthoquinone pigment from the sea urchin Scaphechinus mirabilis, has been studied in clinical trials, when it was used as an active substance of the drug Histochrome® and ...
Larisa N. Bogdanovich, Aleksandr A. Artyukov, Tatyana A. Rutckova, Vyacheslav L. Novikov, Elena A. Zelepuga, Emma P. Kozlovskaya, Natalia M. Lupach   +6 more
core   +1 more source

Free Radical Scavenging Activity of Synthetic and Naturally Occurring Polyhydroxy-, Aminohydroxynaphthazarins and Related Compounds

Natural Product Communications, 2018
Fifty natural and synthetic hydroxy-, aminohydroxynaphthazarins and related quinones were tested for their antiradical activities using 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) scavenging assay.
Nikita S. Polonik, Yuri E. Sabutskii, Sergey G. Polonik   +2 more
doaj   +1 more source

Hystochrome influence on physical endurance of rats

Бюллетень сибирской медицины, 2016
Introduction. Domestic antioxidant drugs series «Gistohrom®» are based on the marine natural compounds echinochrome A. «Gistohrom®»activates cell energy metabolism and protein synthesis, increases the body’s endurance under extreme physical exertion. The
O. S. Talalaeva, Ya. F. Zverev, V. M. Bryukhanov   +2 more
doaj   +1 more source

Protective effect of Echinochrome against intrahepatic cholestasis induced by alpha-naphthylisothiocyanate in rats

, 2020
The present study was designed to evaluate the protective effects of echinochrome (Ech) on intrahepatic cholestasis in rats induced by a single (i.p.) injection of alpha-naphthylisothiocyanate (ANIT) (75 mg/kg body weight).
Sohair R Fahmy (6624644), Nesreen Y Almortada (6624653), Amel M Soliman (6624650), Wafaa E Abd-El Aal (6624656), Dawlat A Sayed (6624647)   +4 more
core   +1 more source

New Aminonaphthoquinone from the Sea Urchins and

Natural Product Communications, 2016
The aminonaphthoquinone, spinamine E ( 5 ), was isolated for the first time from the sea urchins Strongylocentrotus pallidus (Sars G.O., 1872) and Mesocentrotus nudus (A. Agassiz, 1864). The structure of 5 was elucidated as 2-amino-3,5,6,7,8-pentahydroxy-
Elena A. Vasileva, Natalia P. Mishchenko, Pavel A. Zadorozhny, Sergey A. Fedoreyev   +3 more
doaj   +1 more source

Natural Substances vs. Approved Drugs in the Treatment of Main Cardiovascular Disorders-Is There a Breakthrough? [PDF]

Antioxidants (Basel), 2023
Grujić-Milanović J, Rajković J, Milanović S, Jaćević V, Miloradović Z, Nežić L, Novaković R.   +6 more
europepmc   +1 more source

Quinoid Pigments of Sea Urchins Scaphechinus mirabilis and Strongylocentrotus intermedius: Biological Activity and Potential Applications. [PDF]

Mar Drugs, 2022
Ageenko NV, Kiselev KV, Odintsova NA.
europepmc   +1 more source

Echinochrome Ameliorates Physiological, Immunological, and Histopathological Alterations Induced by Ovalbumin in Asthmatic Mice by Modulating the Keap1/Nrf2 Signaling Pathway. [PDF]

Mar Drugs, 2023
Abdelmawgood IA, Mahana NA, Badr AM, Mohamed AS, Al Shawoush AM, Atia T, Abdelrazak AE, Sakr HI.   +7 more
europepmc   +1 more source

Protective effect of Echinochrome against intrahepatic cholestasis induced by alpha-naphthylisothiocyanate in rats

, 2019
The present study was designed to evaluate the protective effects of echinochrome (Ech) on intrahepatic cholestasis in rats induced by a single (i.p.) injection of alpha-naphthylisothiocyanate (ANIT) (75 mg/kg body weight).
Sohair R Fahmy (6624644), Sohair R Fahmy, Nesreen Y Almortada (6624653), Amel M Soliman (6624650), Amel M Soliman, Wafaa E Abd-El Aal, Dawlat A Sayed, Nesreen Y Almortada, Wafaa E Abd-El Aal (6624656), Dawlat A Sayed (6624647)   +9 more
core   +1 more source