Results 41 to 50 of about 459,500 (288)

Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis

Frontiers in Oncology, 2022
Integrin α11β1 is a collagen-binding integrin that is needed to induce and maintain the myofibroblast phenotype in fibrotic tissues and during wound healing.
Guillermo A. Martínez-Nieto, Hanna-Riikka Teppo, Hanna-Riikka Teppo, Hanna-Riikka Teppo, Noora Petrelius, Valerio Izzi, Valerio Izzi, Valerio Izzi, Raman Devarajan, Tiina Petäistö, Hengshuo Liu, Kris S. Kim, Sanna-Maria Karppinen, Heli Ruotsalainen, Jarkko Koivunen, Joni M. Mäki, Gilbert C. Walker, Taina Pihlajaniemi, Donald Gullberg, Ritva Heljasvaara, Ritva Heljasvaara   +20 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Programi namenjeni starševstvu, kot pomemben člen promocije duševnega zdravja

Revija za Zdravstvene Vede, 2023
Namen prispevka je predstaviti pomen in učinkovitost različnih programov, ki so namenjeni staršem in predstavljajo potencial za promocijo duševnega zdravja in krepitev javnega zdravja v Republiki Sloveniji. Programi, ki se v svetu množično ustanavljajo,
Helena Grmek, Nikolaj Lipič
doaj   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Implementing Dual Base Stations within an IoT Network for Sustaining the Fault Tolerance of an IoT Network through an Efficient Path Finding Algorithm

Sensors, 2023
The IoT networks for implementing mission-critical applications need a layer to effect remote communication between the cluster heads and the microcontrollers. Remote communication is affected through base stations using cellular technologies.
J. K. R. Sastry, Bhupati Ch, Raja Rao Budaraju   +2 more
doaj   +1 more source

Measurement of collagen synthesis by cells grown under different mechanical stimuli [PDF]

, 2006
INTRODUCTION: The use of scaffolds in tissue engineering is essential to provide cells with a matrix for cell proliferation and differentiation resulting in tissue regeneration.
Brown, R, Foroughi, F, Mudera, V
core  

IFN-γ-producing CD4+ T cells promote experimental cerebral malaria by modulating CD8+ T cell accumulation within the brain.

, 2012
It is well established that IFN-γ is required for the development of experimental cerebral malaria (ECM) during Plasmodium berghei ANKA infection of C57BL/6 mice. However, the temporal and tissue-specific cellular sources of IFN-γ during P.
Blount, Daniel G, Couper, Kevin N, de Souza, J Brian, Greig, Rachel, Gwyer Findlay, Emily, Hafalla, Julius CR, Hunter, Christopher A, Riley, Eleanor M, Shaw, Tovah N, Stumhofer, Jason S, Villegas-Mendez, Ana   +10 more
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

THE FORECASTING OF THE RESIDUAL RESOURCE OF ELECTRONIC ENGINE CONTROL SYSTEM

Вестник СибАДИ, 2017
In the article authors have given the results of research operating reliability of electronic engine control module systems (ECM), substantiated the set of diagnostic parameters for the estimation of the technical condition of the subsystems (ECM) and ...
Y. V. Bazhenov, V. P. Kalenov
doaj   +1 more source

Mechanical Forces as Determinants of Disseminated Metastatic Cell Fate

Cells, 2020
Disseminated metastatic cancer cells represent one of the most relevant causes of disease relapse and associated death for cancer patients, and a therapeutic target of the highest priority.
Marco Montagner, Sirio Dupont
doaj   +1 more source