Results 61 to 70 of about 469,615 (331)
A Novel 3D Scaffold for Cell Growth to Assess Electroporation Efficacy
Cells, 2019 Tumor electroporation (EP) refers to the permeabilization of the cell membrane by means of short electric pulses thus allowing the potentiation of chemotherapeutic drugs.
Monica Dettin +9 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Clinical and Translational ScienceN,N‐dimethylacetamide (DMA) is an organic solvent, used in busulphan, iv‐formulation, (Busulfex). DMA is metabolized primarily to N‐methylacetamide (MMA) via CYP2E1.
Fadwa Benkessou +16 more
doaj +1 more source
Forecasting Macroeconomic Variables and their Effect on Poverty
Journal of Economics, Business & Accountancy Ventura, 2023 Forecasting macroeconomic variables is crucial to measure dynamic changes during uncertain economic conditions. This study examines and analyzes the appropriate and accurate forecasting model to predict macroeconomic variables in Maluku Province.
Muhammad Ridhwan Assel +3 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Folia Veterinaria, 2019 The aim of our study was to examine the effects of passive and active cell seeding techniques on in vitro chondrogenic differentiation of mesenchymal stem cells (MSC) isolated from rat bone marrow and seeded on porous biopolymer scaffolds based on ...
Giretová M. +5 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Tumor and ECM dynamics for various ECM strain-stress coefficients.
, 2021 Superimposed “slices” through the center of the tumor at times 100, 200,…, 500. Tumor volume fractions—black, ECM—red. A: k3 = 1 (low excess pressure). B: k3 = 5. C: k3 = 25 (high excess pressure). Note that higher k3 means higher resistance from ECM and
Gregory Baramidze (11719135) +2 more
core +1 more source
, 2014 The consequence of numerous neurological disorders is the significant loss of neural cells, which further results in multilevel dysfunction or severe functional deficits. The extracellular matrix (ECM) is of tremendous importance for neural regeneration mediating ambivalent functions: ECM serves as a growth-promoting substrate for neurons but, on the ...
Estrada, V. +2 more
openaire +5 more sources