Results 61 to 70 of about 378,182 (255)
NF-κB signaling and crosstalk during carcinogenesis
4 open, 2019 Transcription factors (TFs) are proteins that control the transcription of genetic information from DNA to mRNA by binding to specific DNA sequences either on their own or with other proteins as a complex.
Brücher Björn L.D.M. +2 more
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Responsabile Scientifico Corso ECM: “Progetto Glaucoma”
, 2017 Corso ECM sulla corretta diagnosi e follow-up della neuropatia glaucomatosa applicando un nuovo algoritmo nato da una collaborazione tra i maggiori specialisti italiani sotto il patrocinio dl Registro Italiano del ...
giovanni milano
core
Macrophage phenotype in response to ECM bioscaffolds [PDF]
, 2017 Macrophage presence and phenotype are critical determinants of the healing response following injury. Downregulation of the pro-inflammatory macrophage phenotype has been associated with the therapeutic use of bioscaffolds composed of extracellular ...
Madeline C. Cramer +23 more
core +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
, 2013 (A) Schematic representation of a cell and some of the associated ECM components. Note how the ECM forms in close proximity to the cell that produces it. Image is adapted from:http://courses.cm.utexas.edu/jrobertus/ch339k/overheads-2/figure-07-30.jpg. (B)
Salvatore Torquato (52468) +1 more
core +1 more source
MiR-29/Hsp47 in ECM network [PDF]
, 2015 Comments on: Chaperone hsp47 drives malignant growth and invasion by modulating an ECM gene network.
Ren Xu, Xu, Ren
core +1 more source
The ECM and tumor volume fractions over the domain.
, 2021 A: Non-homogeneous ECM. B: Asymmetrical tumor shape as a result of non-homogeneous ECM.
Gregory Baramidze (11719135) +2 more
core +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source