Results 81 to 90 of about 469,615 (331)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Time-course expression of major components of the chondrocyte-associated extracellular matrix (ECM)
, 2011 Copyright information:Taken from "Microenvironmental changes during differentiation of mesenchymal stem cells towards chondrocytes"http://arthritis-research.com/content/9/2/R33Arthritis Research & Therapy 2007;9(2):R33-R33.Published online 29 Mar ...
Danièle Noël (60674) +9 more
core +1 more source
Programi namenjeni starševstvu, kot pomemben člen promocije duševnega zdravja
Revija za Zdravstvene Vede, 2023 Namen prispevka je predstaviti pomen in učinkovitost različnih programov, ki so namenjeni staršem in predstavljajo potencial za promocijo duševnega zdravja in krepitev javnega zdravja v Republiki Sloveniji. Programi, ki se v svetu množično ustanavljajo,
Helena Grmek, Nikolaj Lipič
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Acta Biomaterialia, 2019 Cardiac tissue engineering provides unique opportunities for cardiovascular disease modeling, drug testing, and regenerative medicine applications. To recapitulate human heart tissue, we combined human induced pluripotent stem cell-derived cardiomyocytes
Idit Goldfracht +11 more
semanticscholar +1 more source
Acta Biomaterialia, 2020 Low back pain resulting from intervertebral disc (IVD) degeneration is a significant socioeconomic burden. The main effect of the degeneration process involves the alteration of the nucleus pulposus (NP) via cell-mediated enzymatic breakdown of key ...
C. Borrelli, C. T. Buckley
semanticscholar +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Journal of Indonesian Applied Economics, 2020 The national economic growth that is quite high is not necessarily detached from the existence of important issues such as limited accumulation of national saving capital, domestic needs that are still highly dependent on imported goods, weak of export ...
M. Rismawan Ridha, Novia Budi Parwanto
doaj +1 more source
3D bioprinted mammary organoids and tumoroids in human mammary derived ECM hydrogels
Acta Biomaterialia, 2019 The extracellular matrix (ECM) of tissues is an important mediator of cell function. Moreover, understanding cellular dynamics within their specific tissue context is also important for developmental biology, cancer research, and regenerative medicine ...
P. Mollica +7 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source