Results 71 to 80 of about 469,615 (331)

Proteomic profiling of the ECM of xenograft breast cancer metastases in different organs reveals distinct metastatic niches

Cancer Research, 2020
Tumor and stromal cells together create distinct ECM niches in breast cancer metastases to various tissues, providing new insight into how tumor cells adapt to survive in different tissue environments.
Jess D. Hebert, S. Myers, A. Naba, Genevieve Abbruzzese, John M. Lamar, S. Carr, R. Hynes   +6 more
semanticscholar   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

ERROR CORRECTION MODEL ANALYSIS OF THE DETERMINANT OF STABILITY OF FINANCIAL SYSTEM IN INDONESIA

Jurnal Lebesgue, 2020
The current condition of economic openness is both an opportunity and a challenge that must be faced wisely by the government. Liberalization and economic integration will have an impact on financial market liberalization, which is highly vulnerable to ...
Muhammad Rismawan Ridha
doaj   +1 more source

Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis

Frontiers in Oncology, 2022
Integrin α11β1 is a collagen-binding integrin that is needed to induce and maintain the myofibroblast phenotype in fibrotic tissues and during wound healing.
Guillermo A. Martínez-Nieto, Hanna-Riikka Teppo, Hanna-Riikka Teppo, Hanna-Riikka Teppo, Noora Petrelius, Valerio Izzi, Valerio Izzi, Valerio Izzi, Raman Devarajan, Tiina Petäistö, Hengshuo Liu, Kris S. Kim, Sanna-Maria Karppinen, Heli Ruotsalainen, Jarkko Koivunen, Joni M. Mäki, Gilbert C. Walker, Taina Pihlajaniemi, Donald Gullberg, Ritva Heljasvaara, Ritva Heljasvaara   +20 more
doaj   +1 more source

Transcriptome profiling revealed multiple genes and ECM-receptor interaction pathways that may be associated with breast cancer

Cellular & Molecular Biology Letters, 2019
Exploration of the genes with abnormal expression during the development of breast cancer is essential to provide a deeper understanding of the mechanisms involved.
Yulong Bao, Li Wang, Lin Shi, Fen Yun, Xia Liu, Yongxia Chen, Chen Chen, Yanni Ren, Yong-Feng Jia   +8 more
semanticscholar   +1 more source

Feeling Things Out: Bidirectional Signaling of the Cell-ECM Interface, Implications in the Mechanobiology of Cell Spreading, Migration, Proliferation, and Differentiation

Advanced Healthcare Materials, 2020
Biophysical cues stemming from the extracellular environment are rapidly transduced into discernible chemical messages (mechanotransduction) that direct cellular activities–placing the extracellular matrix (ECM) as a potent regulator of cell behavior ...
Andrew E. Miller, P. Hu, T. Barker
semanticscholar   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Synopsis: Special Issue on “Disruption of signaling homeostasis induced crosstalk in the carcinogenesis paradigm Epistemology of the origin of cancer”

4 open, 2019
It is increasingly evident that carcinogenesis, in the vast majority of cancers, cannot be explained simply through an accumulation of somatic mutations, or epigenetics, the stem cell theory, or the Warburg effect.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source

Implementing Dual Base Stations within an IoT Network for Sustaining the Fault Tolerance of an IoT Network through an Efficient Path Finding Algorithm

Sensors, 2023
The IoT networks for implementing mission-critical applications need a layer to effect remote communication between the cluster heads and the microcontrollers. Remote communication is affected through base stations using cellular technologies.
J. K. R. Sastry, Bhupati Ch, Raja Rao Budaraju   +2 more
doaj   +1 more source

A Photo-crosslinkable Kidney ECM-derived Bioink Accelerates Renal Tissue Formation

Advanced Healthcare Materials, 2019
3D bioprinting strategies in tissue engineering aim to fabricate clinically applicable tissue constructs that can replace the damaged or diseased tissues and organs.
Mohamed Ali, A. Pr, J. Yoo, F. Zahran, A. Atala, Sang-Jin Lee   +5 more
semanticscholar   +1 more source