Results 51 to 60 of about 472,334 (294)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Effects of Cell Seeding Methods on Chondrogenic Differentiation of Rat Mesenchymal Stem Cells in Polyhydroxybutyrate/Chitosan Scaffolds

Folia Veterinaria, 2019
The aim of our study was to examine the effects of passive and active cell seeding techniques on in vitro chondrogenic differentiation of mesenchymal stem cells (MSC) isolated from rat bone marrow and seeded on porous biopolymer scaffolds based on ...
Giretová M., Medvecký Ľ., Petrovová E., Čížková D., Mudroňová D., Danko J.   +5 more
doaj   +1 more source

Upregulated integrin α11 in the stroma of cutaneous squamous cell carcinoma promotes skin carcinogenesis

Frontiers in Oncology, 2022
Integrin α11β1 is a collagen-binding integrin that is needed to induce and maintain the myofibroblast phenotype in fibrotic tissues and during wound healing.
Guillermo A. Martínez-Nieto, Hanna-Riikka Teppo, Hanna-Riikka Teppo, Hanna-Riikka Teppo, Noora Petrelius, Valerio Izzi, Valerio Izzi, Valerio Izzi, Raman Devarajan, Tiina Petäistö, Hengshuo Liu, Kris S. Kim, Sanna-Maria Karppinen, Heli Ruotsalainen, Jarkko Koivunen, Joni M. Mäki, Gilbert C. Walker, Taina Pihlajaniemi, Donald Gullberg, Ritva Heljasvaara, Ritva Heljasvaara   +20 more
doaj   +1 more source

A joint OFDM PAPR reduction and data decoding scheme with no SI estimation [PDF]

, 2016
The need for side information (SI) estimation poses a major challenge when selected mapping (SLM) is implemented to reduce peak-to-average power ratio (PAPR) in orthogonal frequency division multiplexing (OFDM) systems.
Adegbite, Saheed A., McMeekin, Scott G., Stewart, Brian G.   +2 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

ERROR CORRECTION MODEL ANALYSIS OF THE DETERMINANT OF STABILITY OF FINANCIAL SYSTEM IN INDONESIA

Jurnal Lebesgue, 2020
The current condition of economic openness is both an opportunity and a challenge that must be faced wisely by the government. Liberalization and economic integration will have an impact on financial market liberalization, which is highly vulnerable to ...
Muhammad Rismawan Ridha
doaj   +1 more source

Implementing Dual Base Stations within an IoT Network for Sustaining the Fault Tolerance of an IoT Network through an Efficient Path Finding Algorithm

Sensors, 2023
The IoT networks for implementing mission-critical applications need a layer to effect remote communication between the cluster heads and the microcontrollers. Remote communication is affected through base stations using cellular technologies.
J. K. R. Sastry, Bhupati Ch, Raja Rao Budaraju   +2 more
doaj   +1 more source

Error-correction Mechanism Tests for Cointegration in a Single-equation Framework [PDF]

, 1998
A new test is proposed for cointegration in a single-equation framework where the regressors are weakly exogenous for the parameters of interest. The test is denoted as an error-correction mechanism (ECM) test and is based upon the ordinary least squares
Banerjee, Anindya, Dolado, Juan José, Mestre, Ricardo   +2 more
core   +4 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Synopsis: Special Issue on “Disruption of signaling homeostasis induced crosstalk in the carcinogenesis paradigm Epistemology of the origin of cancer”

4 open, 2019
It is increasingly evident that carcinogenesis, in the vast majority of cancers, cannot be explained simply through an accumulation of somatic mutations, or epigenetics, the stem cell theory, or the Warburg effect.
Brücher Björn L.D.M., Jamall Ijaz S.
doaj   +1 more source