Results 51 to 60 of about 378,182 (255)

ECM.

, 2013
In 3D culture, our model allows for the investigation of a cross section of the system and the cells that are immersed in ECM. In 2D, the contact region of the ECM and the cell is a line that surrounds the cell; therefore, an enclosed curve (or ring) can
Mohammad Azimi (343458), Yousef Jamali (218858), Mohammad R. K. Mofrad (218868)   +2 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

The Effect of Foreign Direct Investment, Human Development and Macroeconomic Condition on Economic Growth: Evidence from Indonesia

Journal of Indonesian Applied Economics, 2020
The national economic growth that is quite high is not necessarily detached from the existence of important issues such as limited accumulation of national saving capital, domestic needs that are still highly dependent on imported goods, weak of export ...
M. Rismawan Ridha, Novia Budi Parwanto
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

β-Adrenoceptor Signaling Activation Improves Bladder Fibrosis by Inhibiting Extracellular Matrix Deposition of Bladder Outlet Obstruction

Frontiers in Bioscience-Landmark
Background: Partial bladder outlet obstruction (pBOO) causes deposition of extracellular matrix (ECM), promotes bladder fibrosis, and decreases bladder compliance. Methods:
Junyu Lai, Guo Chen, Hongwei Su, Qing He, Kaiwen Xiao, Banghua Liao, Jianzhong Ai   +6 more
doaj   +1 more source

Changes in tension regulates proliferation and migration of fibroblasts by remodeling expression of ECM proteins

, 2016
Wound healing is a complicated but highly organized process in which cell migration and proliferation are actively involved. However, the process by which mechanical stretch regulates the proliferation and migration of human skin fibroblasts (HFs) and ...
Zhang LL, Luo XD, 龙勉, Qiu JH, Che, L, Chen, L (reprint author), Third Mil Med Univ, Southwest Hosp, Breast Dis Ctr, 30 Gaotanyan St, Chongqing 400038, Peoples R China., Luo, XD (reprint author), Third Mil Med Univ, Burn Res Inst, Southwest Hosp, 30 Gaotanyan St, Chongqing 400038, Peoples R China., Lu DY, Jiang MM   +8 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Causality between Economic Growth and Consumption of Natural Gas in I. R. Iran [PDF]

Pizhūhishnāmah-i Iqtiṣād-i Inirzhī-i Īrān, 2012
This study investigates interactions between economic growth and natural gas consumption, using times series data. The paper uses vector error correction technique and Johansen Co-integration test for the period 1353-1386.
Teymoor Mohammadi, Azadeh Bordbar, Alireza Daghighi Asli   +2 more
doaj  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

ECM at Work [PDF]

, 2012
The performance of the elliptic curve method (ECM) for integer factorization plays an important role in the security assessment of RSA-based protocols as a cofactorization tool inside the number field sieve.
Thorsten Kleinjung, Joppe W. Bos
core   +1 more source