Results 41 to 50 of about 472,334 (294)

The impact of educational expenditures of government on economic growth of Iran

AD-minister, 2017
Using the annual data of Iran’s economy from 1981-2012, this study examines Wagner’s law and the Keynesian hypothesis about the relationship between the real government expenditure and the real GDP.
Fozieh Jeyhoon Tabar, Zahra Najafi, Yaser Sistani Badooei   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

A Novel 3D Scaffold for Cell Growth to Assess Electroporation Efficacy

Cells, 2019
Tumor electroporation (EP) refers to the permeabilization of the cell membrane by means of short electric pulses thus allowing the potentiation of chemotherapeutic drugs.
Monica Dettin, Elisabetta Sieni, Annj Zamuner, Ramona Marino, Paolo Sgarbossa, Maria Lucibello, Anna Lisa Tosi, Flavio Keller, Luca Giovanni Campana, Emanuela Signori   +9 more
doaj   +1 more source

Forecasting Macroeconomic Variables and their Effect on Poverty

Journal of Economics, Business & Accountancy Ventura, 2023
Forecasting macroeconomic variables is crucial to measure dynamic changes during uncertain economic conditions. This study examines and analyzes the appropriate and accurate forecasting model to predict macroeconomic variables in Maluku Province.
Muhammad Ridhwan Assel, Bin Raudha Arif Hanoeboen, Abdul Aziz Laitupa, Fibryano Saptenno   +3 more
doaj   +1 more source

Normal versus pathological cardiac fibroblast-derived extracellular matrix differentially modulates cardiosphere-derived cell paracrine properties and commitment [PDF]

, 2017
Human resident cardiac progenitor cells (CPCs) isolated as cardiosphere-derived cells (CDCs) are under clinical evaluation as a therapeutic product for cardiac regenerative medicine.
Angelini, Francesco, BIONDI ZOCCAI, Giuseppe, Castaldo, Clotilde, Chimenti, Isotta, Frati, Giacomo, Maiello, Ciro, Meglio, Franca di, Messina, Elisa, Nurzynska, Daria, Pagano, Francesca, Picchio, Vittorio, Sciarretta, Sebastiano   +11 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Characteristic numbers to describe the detail transfer quality of electro-chemical machining [PDF]

, 1984
For reproducing processes such as electrochemical machining (ecm) the accuracy of the reproduction is an important process parameter. Characteristic numbers which are a measure of this accuracy are proposed in this paper.
Meijer, J., Veringa, J.C.M.
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pharmacokinetics and Toxicity of Dimethylacetamide and Its Metabolite in Pediatric Patients Treated With High Dose Intravenous Busulphan

Clinical and Translational Science
N,N‐dimethylacetamide (DMA) is an organic solvent, used in busulphan, iv‐formulation, (Busulfex). DMA is metabolized primarily to N‐methylacetamide (MMA) via CYP2E1.
Fadwa Benkessou, Ibrahim El‐Serafi, Rui He, Yikai Yin, Limei Ma, Xiaoli Li, Ahmed T. El‐Serafi, Ylva Terelius, Tayfun Gungör, Manuchehr Abedi‐Valugerdi, Tingting Wang, Weiyi Zheng, Chao Yu, Weiying Zhou, Massoud Vosough, Ying Zhao, Moustapha Hassan   +16 more
doaj   +1 more source

Long-range mechanical force in colony branching and tumor invasion [PDF]

, 2011
The most concerned factors for cancer prognosis are tumor invasion and metastasis. The patterns of tumor invasion can be characterized as random infiltration to surrounding extracellular matrix (ECM) or formation of long-range path for collective ...
Guo, Chin-Lin, Maslov, Jordan, Ouyang, Mingxing, Price, Andrew, Yu, Jiun-Yann   +4 more
core   +1 more source