Results 41 to 50 of about 1,822 (135)

A Randomized Double-Blinded Dose-dependent Study of Metaraminol for Preventing Spinal-Induced Hypotension in Caesarean Delivery

open access: yesFrontiers in Pharmacology, 2021
Purpose: Prophylactic infusion of a vasopressor is preferred as a rational choice in clinical practice in Cesarean delivery. Metaraminol is one of most common vasopressors used in obstetric clinical practice. However, the dose-response of metaraminol has
Fei Xiao   +5 more
doaj   +1 more source

In vitro study of baseline sensitivity of important fungi against different fungicides [PDF]

open access: yes, 2012
Baseline sensitivity values of important phytopathogenic fungi were studied against fungicides. ED50, ED90 and MIC value of propiconazole for, Colletotrichum capsici, and Gloeosporium ampelophagum was in the range of 0.020-0.04 ?g/ml.
Nagrale, Dipak T.   +5 more
core   +1 more source

Study on anisotropic behavior of 7075 Al alloy after extrusion

open access: yesMaterials Research Express, 2022
For an extrusion process of 7075 Al alloy, the extrusion direction of the initial blank is changed to study the mechanical properties of the formed plates and characterize their microstructure. The as-received bar is extruded 7075 Al alloy. The secondary
Yi Zhang   +7 more
doaj   +1 more source

Repurposing Drugs for Malaria through a Human Dose Prediction: A Case Study with Berzosertib

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Repurposing drugs whose clinical safety has been established offers a valuable approach to reduce the cost and time associated with the development of new drugs for malaria. Here, we investigate the potential to repurpose the anticancer kinase inhibitor berzosertib for the treatment of malaria, by assessing whether a predicted efficacious human dose ...
Devasha Redhi   +5 more
wiley   +1 more source

Steaming soil is effective in eliminating invasive alien plants (IAPs) – part I: effect of exposure method

open access: yesPest Management Science, Volume 81, Issue 4, Page 2032-2039, April 2025.
As regulations on chemical pesticides become more stringent, it is likely that there will be interest in water steam as an alternative approach for soil disinfestation. This study investigated the feasibility of utilizing a soil steaming device for thermal control of selected invasive alien plants and showed a promising mortality rate for their ...
Zahra Bitarafan   +4 more
wiley   +1 more source

Combination Index values obtained at ED50, ED75 and ED90. The average of the three values is reported in the last row.

open access: yes, 2012
Combination Index values obtained at ED50, ED75 and ED90. The average of the three values is reported in the last row.
Monica Ceccon (114489)   +3 more
core   +1 more source

Projecting future damage costs of non‐native species using combined dynamical and cost–density equations

open access: yesEcological Applications, Volume 36, Issue 5, July 2026.
Abstract Biological invasions threaten biodiversity, economic stability, and public health, exacerbated by intensive global trade and transport. The economic costs of these invasions have exceeded US$2 trillion globally and continue to increase. Although past invasion costs have been described across various contexts, there are few robust projections ...
Danish A. Ahmed   +11 more
wiley   +1 more source

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1005-1015, April 2026.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin   +6 more
wiley   +1 more source

A Novel Topical Emollient Plus for Canine Atopic Dermatitis: A Clinical Trial Assessing Efficacy and User Acceptance

open access: yesVeterinary Dermatology, Volume 37, Issue 2, Page 293-305, April 2026.
Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes   +8 more
wiley   +1 more source

Sowing date and seeding rate influence cereal rye productivity across the Northeastern United States

open access: yesAgronomy Journal, Volume 118, Issue 2, March/April 2026.
Abstract Improving the management of cereal rye (Secale cereale L.), the most frequently used cover crop in the United States, provides an opportunity to enhance agroecosystem service provisioning. Services such as erosion control, weed suppression, and nitrate leaching mitigation are correlated with cereal rye ground cover and biomass, which decline ...
Laurel Wellman   +16 more
wiley   +1 more source

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