Results 21 to 30 of about 1,822 (135)

Unveiling the Antimalarial Potential of Leaf Extracts of <i>Mussaenda erythrophylla</i> Schum. & Thonn. and <i>Mussaenda philippica Dona Luz</i> x <i>M. flava</i> in Mice. [PDF]

J Trop Med
Malaria remains a major global public health concern, particularly in tropical regions. The increasing resistance to the current antimalarial drugs highlights the urgent need for new and effective therapies. Medicinal plants offer a promising source of novel and affordable antimalarial compounds for drug development.
Chaniad P, Phuwajaroanpong A, Plirat W, Konyanee A, Viriyavejakul P, Septama AW, Punsawad C.   +6 more
europepmc   +2 more sources

Dose-Response Relationship of Single Intravenous Remimazolam on Bispectral Index and Cardiorespiratory Effects [PDF]

Drug Design, Development and Therapy
Jianxiao Chen,1,* Jianqiao Luo,1,* Honglan Ye,1 Hao Lv,1 Wenyao Li,1 Fangfang Luo,1 Youmei Zhou,1 Fei Xiao,2 Chen Lv,3 Xiaowen Guo,3 Shaoqiang Huang41Department of Anesthesia, Shaoxing Shangyu Maternal and Child Health Hospital, Zhejiang, 312300, People ...
Chen J, Luo J, Ye H, Lv H, Li W, Luo F, Zhou Y, Xiao F, Lv C, Guo X, Huang S   +10 more
doaj   +2 more sources

Labor Analgesia Initiation with Dural Puncture Epidural versus Standard Epidural Techniques: A Prospective Randomized Dose Allocation Study of Ropivacaine [PDF]

Drug Design, Development and Therapy
Fei Xiao,1,2 Dan M Drzymalski,3 Yu-Fang Dong,2 Jia-Yue Huang,2 Yan Gao,2 Hai-Ya Yan,1 Hui-Jing Hu2 1Department of Anesthesiology, The Affiliated Women and Children’s Hospital of Ningbo University, Ningbo, People’s Republic of China; 2Department of ...
Xiao F, Drzymalski DM, Dong YF, Huang JY, Gao Y, Yan HY, Hu HJ   +6 more
doaj   +2 more sources

Determination of ED90s of Phenylephrine and Norepinephrine Infusion for Strict Blood Pressure Management Targets in Preeclamptic Patients Undergoing Cesarean Section: A Randomized Sequential Allocation Study [PDF]

Drug Design, Development and Therapy
Yueji Ma,&ast; Rong Ma,&ast; Yongqiang Shi, Rui Qin, Yi Chen Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, People’s Republic of China&ast;These authors contributed equally ...
Ma Y, Ma R, Shi Y, Qin R, Chen Y
doaj   +2 more sources

The effective dose of remimazolam in combination with sufentanil for sedation during transvaginal oocyte retrieval: an up-and-down sequential allocation trial [PDF]

BMC Anesthesiology
Background The potential adverse effects of propofol on fertilization outcomes have raised concerns among patients undergoing anesthesia for oocyte retrieval. Remimazolam is a new type of ultra-short-acting benzodiazepine.
Yanfei Lu, Gongchen Duan, Jiafeng Fu, Foquan Luo, Bin Wang, Junhui Lang   +5 more
doaj   +2 more sources

Determine of 90% Effective Dose of Oliceridine Combined with Etomidate for Inhibiting Laryngeal Mask Airway Insertion Responses in Patients of Different Ages: A Biased-Coin Sequential Allocation Dose-Finding Trial [PDF]

Drug Design, Development and Therapy
Fangsheng Xu,1,&ast; Yuanyuan Cui,2,&ast; Zhengle Wang,1 Rongguang Liu,1 Jian Tang,1 Yuan Xu,1 Luoyun Li,3 Chunyu Li,4 Meifang Wang,1 Jianfeng Pu1 1Department of Anesthesiology, Changshu No.
Xu F, Cui Y, Wang Z, Liu R, Tang J, Xu Y, Li L, Li C, Wang M, Pu J   +9 more
doaj   +2 more sources

A study to determine minimum effective dose of oxytocin infusion during caesarean delivery in parturients at high risk of uterine atony

Journal of Obstetric Anaesthesia and Critical Care, 2017
Background: Oxytocin, a commonly used drug to prevent uterine atony after caesarean section, should be administered as dilute rapid infusion rather than as a bolus. This study was conducted to calculate ED90 of oxytocin infusion during caesarean delivery
Shashikiran, Harsimran Kaur, Renu Bala, Neha Gupta   +3 more
doaj   +2 more sources

A Prospective Randomized Dose-Finding Study of Intrathecal Opioids for Postoperative Analgesia After Minimally Invasive Colorectal Operation [PDF]

Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Objective: To determine the optimal dose of intrathecal morphine and hydromorphone in patients undergoing minimally invasive colorectal operation for postoperative analgesia. Patients and Methods: The study was a double-blinded clinical dosing trial that
Patrice A. Vinsard, MD, Josef Pleticha, MD, Emily E. Sharpe, MD, Jason K. Panchamia, DO, David A. Olsen, MD, Hans P. Sviggum, MD, Sherief F. Shawki, MB, MD, Kevin T. Behm, MD, David W. Larson, MD, MBA, Allison M. LeMahieu, MS, Adam D. Niesen, MD, Adam W. Amundson, MD   +11 more
doaj   +2 more sources

Determination of the 90% Effective Dose of Remimazolam Continuous Infusion for Preventing Emergence Delirium in Pediatric Patients Undergoing Adenoidectomy or Adenotonsillectomy with Sevoflurane: A Biased Coin Up-and-Down Sequential Trial Design [PDF]

Drug Design, Development and Therapy
Zhong-Sai Yang, Ding Li, Yu Jiang, Fei Xiao, Hai-Ya Yan Department of Anesthesiology, The Affiliated Women and Children’s Hospital of Ningbo University, Ningbo, Zhejiang, People’s Republic of ChinaCorrespondence: Fei Xiao, Department of Anesthesiology ...
Yang ZS, Li D, Jiang Y, Xiao F, Yan HY
doaj   +2 more sources

Determining the 90% Effective Dose of Remimazolam to Prevent Physical Movement in Surgical Abortions: A Biased-Coin Up-and-Down Sequential Allocation Trial [PDF]

Drug Design, Development and Therapy
Fuquan Fang,1,&ast; Huiling Li,1,&ast; Lei Li,1 Bing Yan,2 Pengfei Yin,1 Binwei Hu,3 Shengmei Zhu,1 Xianhui Kang1 1Department of Anesthesiology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, People’s ...
Fang F, Li H, Li L, Yan B, Yin P, Hu B, Zhu S, Kang X   +7 more
doaj   +2 more sources