Sugammadex ED90 dose to reverse the rocuronium neuromuscular blockade in obese patients
Objective: to determine the ED90 (minimum effective dose in 90% of patients) of sugammadex for the reversal of rocuronium-induced moderate neuromuscular blockade (NMB) in patients with grade III obesity undergoing bariatric surgery.
MAURO PRADO DA SILVA +5 more
doaj +3 more sources
Background: Dose-finding studies in anaesthesiology aim to target the effective dose (ED) of an anaesthetic agent in a specific population. The common dose-finding designs used are the up and down method (UDM), the biased-coin up and down (BCD), and the ...
Jean-François Fils +3 more
doaj +2 more sources
Determining ED90 of Flumazenil for Selective Respiratory Distress Improvement Using Remimazolam During Endoscopic Submucosal Dissection of Gastric Neoplasms: A Prospective Study [PDF]
Background: Patients undergoing endoscopic submucosal dissection under monitored anesthesia care (MAC) with remimazolam may develop respiratory distress during the procedure.
Sung Kwan Shin, Da Hyun Jung, Namo Kim
exaly +3 more sources
Effective doses of remimazolam for sedation in paediatric magnetic resonance imaging following dexmedetomidine premedication: a dose-finding study [PDF]
Background Effective sedation for paediatric magnetic resonance imaging (MRI) requires balancing depth control and safety. This dose-finding study aims to establish the 50% (ED50) and 90% (ED90) effective doses of intravenous remimazolam following ...
Wanjun Zheng +5 more
doaj +2 more sources
The 90% effective dose (ED90) of esketamine for inhibiting responses to intraoperative motor stimulation during ambulatory hysteroscopy: a biased-coin up-and-down sequential allocation trial [PDF]
Background Esketamine and remimazolam co-administration presents a viable opioid-free anesthetic alternative for outpatient hysteroscopy. This study was designed to ascertain the ED90 of esketamine for inhibiting intraoperative movement responses in ...
Ruiqi Zhang +4 more
doaj +2 more sources
Background Prior studies have shown that, when administered as an intravenous bolus to prevent uterine atony, prophylactic phenylephrine infusion increased the dose requirement of oxytocin and second-line uterotonics. For the prevention of uterine atony,
Xiao-Qin Jin +5 more
doaj +2 more sources
Evaluation of a novel laser-system operating at 1940 nm for weed control and determining the influence of biological and operational factors. [PDF]
The control efficacy of a novel laser pulse system operating at 1940 nm was tested. The new system allows effective control of young weeds with 1.5 J. Targeting the plant stem is 53‐fold more energy‐efficient than the meristem. Species morphology and beam diameter significantly influence weed control efficacy. Abstract BACKGROUND This study evaluates a
Lati RN +6 more
europepmc +2 more sources
Laboratory Evaluation of Synthetic Attractants for Anopheles stephensi Using High-Throughput Screening: A Step Towards Development of Mosquito Traps [PDF]
Background: Diseases such as malaria are transmitted by Anopheles species, among which Anopheles stephensi is one of the most important malaria vectors in Iran.
Mohammad Nasrabadi +5 more
doaj +2 more sources
A Study on the ED90 of Esketamine Combined with Ropivacaine for Early Epidural Analgesia During the First Stage of Labor in Nulliparous Women: A Randomized, Sequential Dose-Finding Trial [PDF]
Xiaoqing Lin,* Yunyun Tu,* Peili Qiu, Yuanhui Zhang, Ying Chen, Zhifang Cao Department of Anesthesiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, Fujian, 364000, People’s Republic of China*These ...
Lin X +5 more
doaj +2 more sources
Pharmacodynamics study of remimazolam besylate in anxious patients undergoing gastroscopy: a biased-coin design up-and-down sequential allocation trial [PDF]
Background This study aimed to evaluate the impact of anxiety on the pharmacodynamics of remimazolam besylate in patients undergoing gastroscopy. Methods Patients undergoing gastroscopy were divided into two groups: an anxiety group (Self -rating Anxiety
Bao-Zhu Cha +6 more
doaj +2 more sources

