Genetic Modifiers of ABCA1 Activity Interact with APOE Isoforms to Mediate Alzheimer's Disease Risk
Objective ATP‐binding cassette transporter A1 (ABCA1) has been associated with Alzheimer's disease (AD), but the mechanisms by which it impacts disease risk are unknown. ABCA1 is known to bind apolipoprotein E (ApoE) and catalyze apolipoprotein lipidation.
Andrés Peña‐Tauber +24 more
wiley +1 more source
Cryo-EM structures of a MexB-MexY chimeric efflux pump reveal that large open clefts are intrinsic to the MexY porter domain. [PDF]
Wang J +7 more
europepmc +1 more source
Accessing Citrus and Soybean Flavonoids as Potential Efflux Pump Inhibitors in Drug-Resistant <i>Escherichia coli</i>. [PDF]
Lu WJ, Huang YC, Tai CY, Lin HV.
europepmc +1 more source
Exploring the In Vitro Antibacterial Properties of Milicia regia and Entandrophragma angolensis: Insight Into Their Antibiofilm and Efflux Pump Inhibitory Activities. [PDF]
Korsah S +8 more
europepmc +1 more source
Molecular insights into efflux pump genes in ciprofloxacin- and methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis clinical isolates from Iraq. [PDF]
Jameel TY, Idris AB, Salman MA, Ayvaz A.
europepmc +1 more source
TXA11114: Discovery of an <i>In Vivo</i> Efficacious Efflux Pump Inhibitor (EPI) That Potentiates Levofloxacin Against <i>Pseudomonas aeruginosa</i>. [PDF]
Rosado-Lugo JD +6 more
europepmc +1 more source
ABSTRACT Palm oil, which is extracted from the mesocarp of the fruit of the Elaeis guineensis Jacq. palm tree, is the most widely produced vegetable oil in the world. The extraction of this substance typically utilizes the conventional pressing method, a technique that is advantageous due to its low operating cost and simplified process.
Constantino Lucas Queta +2 more
wiley +1 more source
<i>Pseudomonas aeruginosa</i> tRNA nucleotidyltransferase Cca controls resistance and tolerance to aminoglycoside antibiotics by regulating the MexXY multidrug efflux pump. [PDF]
Shen C +8 more
europepmc +1 more source
ABSTRACT This study carries significant consequences in various engineering applications, such as cooling rotating disk surfaces, improving chemical reactor performance, and designing filtration systems. Considering these main applications in view, the aim of this study is to investigate time‐dependent Casson hybrid nanofluid flow on a permeable ...
Ebrahem A. Algehyne +6 more
wiley +1 more source
Expression of multidrug efflux pump gene acrAB in Escherichia coli: a systematic review and meta analysis. [PDF]
Bahaj SS +8 more
europepmc +1 more source

