Results 161 to 170 of about 71,112 (299)

A Computational Approach for Biomimetic Design of Liver‐On‐A‐Chip

open access: yesAdvanced Intelligent Discovery, EarlyView.
A biomimetic liver‐on‐a‐chip with antiparallel perfusion was designed using COMSOL‐guided simulation to replicate hepatic acinus transport. Full‐scale modelling revealed diffusion‐dominated, length‐dependent nutrient gradients and low‐shear conditions.
Zhenxu Yang   +9 more
wiley   +1 more source

A Study of Gene Expression and Activity of NorA Efflux Pump in Clinical Isolates of Ciprofloxacin Resistant Staphylococcus Aureus

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2016
BACKGROUND AND OBJECTIVE: The existence of efflux pumps such as norA is one the mechanisms of resistance to antibiotics like ciprofloxacin in staphylococcus aureus bacteria. NorA efflux pump and its gene expression and activity in ciprofloxacin resistant
A Mirzaie   +3 more
doaj  

Artificial Intelligence‐Driven Network Pharmacology: A Methodological Paradigm Shift Bridging Traditional Wisdom and Modern Science

open access: yesAdvanced Intelligent Discovery, EarlyView.
Artificial intelligence is redefining network pharmacology (NP). By integrating knowledge graph engineering, geometric deep learning, multiomics anchoring, and generative reasoning, AI‐driven NP (AI‐NP) transforms static target mapping into dynamic, predictive modeling.
Cong Wang   +9 more
wiley   +1 more source

Co‐Occurring Non‐Cardiac Congenital Anomalies Among Cases With Congenital Heart Defects

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cases with congenital heart defects (CHD) often have other associated anomalies. The aim of this investigation was to assess the prevalence and the types of co‐occurring anomalies in CHD in a well‐defined population. The anomalies co‐occurring with CHD were ascertained in all live births, stillbirths and terminations of pregnancy for fetal ...
Claude Stoll   +2 more
wiley   +1 more source

Regional gas exchange evaluation during ex vivo lung perfusion in a swine model of localized lung dysfunction

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Abstract Background Ex vivo lung perfusion (EVLP) allows the evaluation of lungs that do not meet standard transplantation criteria. Current procedures do not permit the identification of regional functional deficits. We investigated the feasibility of assessing lobar gas exchange during EVLP in a swine model.
Giulia Maria Ruggeri   +16 more
wiley   +1 more source

3D-Pharmacophore model studies on MexB efflux pump inhibitor of Pseudomonas aeruginosa : Bachelor Theses

open access: yes, 2020
50 p.In recent years, antimicrobial resistance rates in gram-negative bacteria are increasing rapidly and efflux pump has been found to be related to multi-drug resistance in clinical isolates.
Dinh, Nguyen Thuy Duyen
core  

Idiopathic Intracranial Hypertension Is Characterized by a Distinct Proteomic Profile

open access: yesAnnals of Neurology, EarlyView.
Objectives The pathophysiology of idiopathic intracranial hypertension (IIH) is poorly understood and disease‐specific biomarkers are lacking. We aimed to shed light on IIH pathophysiology and identify disease‐specific biomarkers. Methods This prospective cross‐sectional cohort study included patients with new‐onset IIH and age‐, body mass index‐, and ...
Santosh D. Bhosale   +17 more
wiley   +1 more source

Sustainable Palm Oil Extraction and Trends in the Use of Green Technologies: State‐of‐the‐Art and Future Directions

open access: yesJournal of the American Oil Chemists' Society, EarlyView.
ABSTRACT Palm oil, which is extracted from the mesocarp of the fruit of the Elaeis guineensis Jacq. palm tree, is the most widely produced vegetable oil in the world. The extraction of this substance typically utilizes the conventional pressing method, a technique that is advantageous due to its low operating cost and simplified process.
Constantino Lucas Queta   +2 more
wiley   +1 more source

Molecular detection of AdeABC efflux pump genes in clinical isolates of Acinetobacter baumannii and their contribution in imipenem resistance

open access: yesIranian South Medical Journal, 2014
Backgrand: Multi-drug resistance due to Acinetobacter baumannii strains has become a significant challenge. Efflux pump plays a vital role in the development of resistance in this bacteria.
Ali Reza JaponiNejad   +2 more
doaj  

Bioconvective Unsteady Casson Hybrid Nanofluid Flow on a Variable Darcy Regime Between Two Rotating Disks With Variable Heat Source

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study carries significant consequences in various engineering applications, such as cooling rotating disk surfaces, improving chemical reactor performance, and designing filtration systems. Considering these main applications in view, the aim of this study is to investigate time‐dependent Casson hybrid nanofluid flow on a permeable ...
Ebrahem A. Algehyne   +6 more
wiley   +1 more source

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