Results 11 to 20 of about 167,075 (204)
PLoS Biology, 2022 Bacteria have membrane-spanning efflux pumps to secrete toxic compounds ranging from heavy metal ions to organic chemicals, including antibiotic drugs.
Christopher J Stubenrauch +3 more
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Susceptibility Tests and Predictions of Transporter Profile in Serratia Species
Microorganisms, 2022 Disinfectants and biosecurity are critically important to control microbial diseases. Resistance to disinfectants compromises sectors such as agriculture and healthcare systems.
Gunther J. Staats +3 more
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Microbial Primer: Multidrug efflux pumps [PDF]
, 2023 Multidrug efflux pumps are molecular machines that sit in the bacterial cell membrane and pump molecules out from either the periplasm or cytoplasm to outside the cell.
Blair, Jessica M A; id_orcid +3 more
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Role of efflux pumps, their inhibitors, and regulators in colistin resistance
Frontiers in Microbiology, 2023 Colistin is highly promising against multidrug-resistant and extensively drug-resistant bacteria clinically. Bacteria are resistant to colistin mainly through mcr and chromosome-mediated lipopolysaccharide (LPS) synthesis-related locus variation. However,
Yinhuan Ding +9 more
doaj +1 more source
, 2022 Archive of efflux-pumps inhibitors containing sub-folders named after each compound and its net charge. Every compound's folder contains a total of 20 files distributed into three sub-directories reporting QM (QM/), FF (FF/), and MD (MD ...
Giuliano Malloci (2060875) +5 more
core +1 more source
mSystems, 2021 Multidrug resistance (MDR) efflux pumps are involved in bacterial intrinsic resistance to multiple antimicrobials. Expression of MDR efflux pumps can be either constitutive or transiently induced by various environmental signals, which are typically ...
Di-Yin Li +7 more
doaj +1 more source
Efflux Pumps In Antimicrobial Resistance: Mechanism, Regulation And Therapeutic Implications [PDF]
, 2023 Efflux pumps play a crucial role in antimicrobial resistance, enabling bacteria to extrude a wide range of antibiotics and other antimicrobial compounds, thereby reducing their intracellular concentration and rendering them ineffective. Understanding the
Bidisha Ghosh +5 more
core +1 more source
Number of detected peptides from efflux pumps.
, 2023 Number of detected peptides from efflux pumps.
Holger C. Scholz (9118844) +5 more
core +1 more source
Investigating functional interplay among Escherichia coli efflux pumps and their contributions to fitness [PDF]
, 2023 Bacterial efflux pumps are conserved active export proteins, many of which can provide multidrug resistance. In diderm bacteria, two efflux pump structural types — single-component efflux pumps and cell envelope-spanning multicomponent systems ...
Goetz, James
core +1 more source
Multidrug efflux pumps at the crossroad between antibiotic resistance and bacterial virulence
Frontiers in Microbiology, 2016 Multidrug efflux pumps can be involved in bacterial resistance to antibiotics at different levels. Some efflux pumps are constitutively expressed at low levels and contribute to intrinsic resistance.
Manuel Alcalde-Rico +3 more
doaj +1 more source