Results 51 to 60 of about 85,671 (296)
mBio, 2016 Multidrug efflux pumps provide clinically significant levels of drug resistance in a number of Gram-negative hospital-acquired pathogens. These pathogens frequently carry dozens of genes encoding putative multidrug efflux pumps.
Karl A. Hassan +13 more
doaj +1 more source
BMC Microbiology, 2022 Background Contribution of efflux pumps in development of antimicrobial resistance has been largely addressed in Gram negative and to a much lesser extent in Gram positive bacteria.
Mohammad Hossein Sobhanipoor +3 more
doaj +1 more source
Social interactions in the Burkholderia cepacia complex : biofilms and quorum sensing [PDF]
, 2010 Burkholderia cepacia complex bacteria are opportunistic pathogens that cause respiratory tract infections in susceptible patients, mainly people with cystic fibrosis. There is convincing evidence that B.
Coenye, Tom
core +2 more sources
Interplay between three RND efflux pumps in doxycycline-selected strains of Burkholderia thailandensis. [PDF]
PLoS ONE, 2013 BACKGROUND: Efflux systems are involved in multidrug resistance in most Gram-negative non-fermentative bacteria. We have chosen Burkholderia thailandensis to dissect the development of multidrug resistance phenotypes under antibiotic pressure ...
Fabrice Vincent Biot +9 more
doaj +1 more source
Antibiotics, 2022 Bacterial efflux pumps are among the key mechanisms of resistance against antibiotics and biocides. We investigated whether differential expression levels of the RND-type efflux pumps AdeABC and AdeIJK impacted the susceptibility to commonly used ...
Christina Meyer +6 more
doaj +1 more source
Correlation of ciprofloxacin resistance with the AdeABC efflux system in Acinetobacter baumannii clinical isolates [PDF]
, 2014 Background: Acinetobacter baumannii is one of the most important pathogens capable of colonization in burn patients, leading to drug-resistant wound infections.
Ardebili, A., Lari, A.R., Talebi, M.
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Efflux Pump-mediated Drug Resistance in Burkholderia
Frontiers in Microbiology, 2015 Several members of the genus Burkholderia are prominent pathogens. Infections caused by these bacteria are difficult to treat because of significant antibiotic resistance.
Nicole L Podnecky +4 more
doaj +1 more source
Draft Genome Sequence of the Biofilm-Forming Stenotrophomonas maltophilia Strain 53 [PDF]
, 2015 A clinical strain of Stenotrophomonas maltophilia (designated strain 53) was obtained, and a whole-genome sequence was generated. The subsequent draft whole-genome sequence demonstrated the presence of a number of genes encoding for proteins involved in ...
Akbar, Sirwan +2 more
core +1 more source
Efflux pump-mediated resistance in chemotherapy
Annals of Medical and Health Sciences Research, 2012 Efflux pump mechanisms perform important physiological functions such as prevention of toxin absorption from the gastrointestinal tract, elimination of bile from the hepatocytes, effective functioning of the blood-brain barrier and placental barrier, and renal excretion of drugs.
Ughachukwu, PO, Unekwe, PC
openaire +4 more sources