Results 21 to 30 of about 33,480 (278)

The FADS1 rs174550 Genotype Modifies the n‐3 and n‐6 PUFA and Lipid Mediator Responses to a High Alpha‐Linolenic Acid and High Linoleic Acid Diets

open access: yesMolecular Nutrition &Food Research, Volume 66, Issue 24, December 2022., 2022
This study aimed to explore the differences in the plasma fatty acid and lipid mediator concentrations in response to dietary polyunsaturated fatty acids (PUFA) between carriers of the FADS1 rs174550 TT and CC genotypes. Plasma concentrations of long‐chain PUFAs and their derived bioactive lipid mediators changed in a genotype dependent manner in ...
Topi Meuronen   +10 more
wiley   +1 more source

Toward precision nutrition: A cross‐sectional study on the genetic risks of nutrients deficiencies and eating behaviors among the Orang Asli and Malays

open access: yesPrecision Medical Sciences, Volume 11, Issue 4, Page 146-154, December 2022., 2022
Toward precision nutrition: Genetic risks of nutrients deficiencies and eating behaviors among the Orang Asli and Malays. Abstract This cross‐sectional study aimed to profile 15 genetic markers associated with the risks of nutrient deficiencies and eating disinhibition behaviors that could lead to obesity among the Orang Asli (OA) and the Malays.
Nurul Ain Khoruddin   +5 more
wiley   +1 more source

Effect of omega‐3 polyunsaturated fatty acid supplementation on oxidative stress parameters and sex hormone levels of modern genotype sows

open access: yesVeterinary Medicine and Science, Volume 9, Issue 1, Page 191-202, January 2023., 2023
In this study, we supplemented the diet of breeding sows either with omega‐6 (control) or omega‐3 (experimental) polyunsaturated fatty acids and examined their effects on the antioxidant system and hormone levels of the animals. In the blood levels of molecules indicating oxidative stress we experienced slight changes, but the feeding of omega‐3 fatty ...
Róbert Roszkos   +4 more
wiley   +1 more source

FADS2 function loss at the cancer hotspot 11q13 locus diverts lipid signaling precursor synthesis to unusual eicosanoid fatty acids. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Genes coding for the fatty acid desaturases (FADS1, 2, 3) localized at the cancer genomic hotspot 11q13 locus are required for the biosynthesis of 20 carbon polyunsaturated fatty acids (PUFA) that are direct eicosanoid precursors.
Woo Jung Park   +3 more
doaj   +1 more source

Impact of dietary supplementation of unsaturated and saturated fatty acids on bone strength, fatty acids profile of thigh muscle and immune responses in broiler chickens under heat stress

open access: yesVeterinary Medicine and Science, Volume 9, Issue 1, Page 252-262, January 2023., 2023
Results suggest that there is not beneficial effect of broiler performance due to adding different source of fat in broiler chicken diet under hot condition. Furthermore, the unsaturated fatty acids could improve profile of fatty acids in thigh and enhance immune responses in broiler chickens.
Reza Vakili, Yahya Ebrahimnezhad
wiley   +1 more source

Eicosanoid release is increased by membrane destabilization and CFTR inhibition in Calu-3 cells. [PDF]

open access: yesPLoS ONE, 2009
The antiinflammatory protein annexin-1 (ANXA1) and the adaptor S100A10 (p11), inhibit cytosolic phospholipase A2 (cPLA2alpha) by direct interaction. Since the latter is responsible for the cleavage of arachidonic acid at membrane phospholipids, all three
Florence Borot   +12 more
doaj   +1 more source

Expression and Function of Eicosanoid-Producing Cytochrome P450 Enzymes in Solid Tumors

open access: yesFrontiers in Pharmacology, 2020
Oxylipins derived from the oxidation of polyunsaturated fatty acids (PUFAs) act as important paracrine and autocrine signaling molecules. A subclass of oxylipins, the eicosanoids, have a broad range of physiological outcomes in inflammation, the immune ...
Eric A. Evangelista   +3 more
semanticscholar   +1 more source

Candida albicans and Pseudomonas aeruginosa interaction, with focus on the role of eicosanoids

open access: yesFrontiers in Physiology, 2016
Candida albicans is commonly found in mixed infections with Pseudomonas aeruginosa, especially in the lungs of cystic fibrosis patients. Both of these opportunistic pathogens are able to form resistant biofilms and frequently infect immunocompromised ...
Ruan eFourie   +6 more
doaj   +1 more source

An anti-inflammatory eicosanoid switch mediates the suppression of type-2 inflammation by helminth larval products

open access: yesScience Translational Medicine, 2020
A helminth larval extract and its component Hpb glutamate dehydrogenase induce an anti-inflammatory mediator switch to suppress type-2 inflammation. Tamping down type-2 inflammation Type-2 immunity in allergy and asthma is driven by nonredundant pathways,
Marta de Los Reyes Jiménez   +24 more
semanticscholar   +1 more source

Eicosanoids and cancer

open access: yesClinics, 2018
Eicosanoids are 20-carbon bioactive lipids derived from the metabolism of polyunsaturated fatty acids, which can modulate various biological processes including cell proliferation, adhesion and migration, angiogenesis, vascular permeability and inflammatory responses.
Gomes, Renata Nascimento   +2 more
openaire   +7 more sources

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