Results 61 to 70 of about 33,480 (278)
Chemistry–Methods, EarlyView.A deep learning‐based method Siamese transformer reaction pair (STRP) prediction is presented for identifying important pathways in untargeted LC‐MS/MS metabolomics. STRP accurately predicts metabolic reaction pairs from known metabolites and tandem mass spectra of unannotated metabolic features, which enhance the utility of untargeted metabolomics ...
Han Bao +7 more
wiley +1 more source
Lipid and Corticosteroid Biomarkers Under the Influence of Bisphosphonates
Drug Testing and Analysis, EarlyView.The detection of bisphosphonates is important due to the potential integrity and welfare issues associated with use of these substances. Targeted detection of a nitrogenous and non‐nitrogenous bisphosphonate was detected for 8 h and 28 days post‐administration, respectively.
Kathy Tou +8 more
wiley +1 more source
Effect of washing units of canine red blood cells on storage lesions
Journal of Veterinary Internal Medicine, 2022 Background In humans, washing stored blood products before transfusion reduces storage lesions and incidence of transfusion reactions, but the effectiveness of washing canine blood is unknown. Objectives The objective was to determine if manually washing
Ashley C. Coll +5 more
doaj +1 more source
Frontiers in Immunology, 2023 Immune function changes across the life stages; for example, senior adults exhibit a tendency towards a weaker cell-mediated immune response and a stronger inflammatory response than younger adults.
Johanna von Gerichten +9 more
doaj +1 more source
Journal of Lipid Research, 2010 Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder referred to gastroenterologists. Although the pathophysiology remains unclear, accumulating evidence points to the presence of low-level immune activation both in the ...
Gerard Clarke +8 more
doaj
The FASEB Journal, 2015 Eicosanoids are important vascular regulators, but the phospholipase A2 (PLA2) isoforms supporting their production within the cardiovascular system are not fully understood.
N. Kirkby +11 more
semanticscholar +1 more source
Eicosanoids in skin inflammation [PDF]
Prostaglandins, Leukotrienes and Essential Fatty Acids, 2013 Eicosanoids play an integral part in homeostatic mechanisms related to skin health and structural integrity. They also mediate inflammatory events developed in response to environmental factors, such as exposure to ultraviolet radiation, and inflammatory and allergic disorders, including psoriasis and atopic dermatitis.
openaire +5 more sources
Evidence that the E2-isoprostane, 15-E2t-isoprostane (8-iso-prostaglandin E2) is formed in vivo
Journal of Lipid Research, 1998 D2/E2-isoprostanes are prostaglandin D2/E2-like compounds that are produced in vivo as non-enzymatic products of free radical catalyzed peroxidation of arachidonic acid.
Jason D. Morrow +4 more
doaj
Grasas y Aceites, 2016 The mediterranean diet (MD) reduced the risk of colorectal cancer (CRC), and olive oil, the primary source of fat in the MD, has also been found to have a protective effect. However, animals fed with oleic acid present a high number of intestinal tumours,
C. E. Storniolo, J. J. Moreno
doaj +1 more source
Directed Non-Targeted Mass Spectrometry and Chemical Networking for Discovery of Eicosanoids [PDF]
arXiv, 2018 Eicosanoids and related species are critical, small bioactive mediators of human physiology and inflammation. While ~1100 distinct eicosanoids have been predicted to exist, to date, less than 150 of these molecules have been measured in humans, limiting our understanding of eicosanoids and their role in human biology. Using a directed non-targeted mass
arxiv