Results 111 to 120 of about 31,692 (187)
First‐trimester trophoblast EVs are enriched in anti‐inflammatory proteins, lipids, and immunoregulatory miRNAs. EVT‐EVs reprogram monocytes toward a pro‐resolving phenotype and restore immune homeostasis in RDEB, supporting their potential as offering a scalable off‐the‐shelf therapy for chronic inflammatory diseases.
Nell Hirt +8 more
wiley +1 more source
A complex immune communication between eicosanoids and pulmonary macrophages
International audienceRespiratory viral infections represent a constant threat for human health and urge for a better understanding of the pulmonary immune response to prevent disease severity.
Poschmann, Jeremie +2 more
core +1 more source
Eicosanoids as diagnostics for preterm labor
Despite continuing significant research efforts and an increasing prevalence of preterm labor (PTL) worldwide, a comprehensive understanding of the mechanisms involved remains to be established; such is the complexity of the interactions involved ...
McKirdy, Natalie C. +2 more
core +1 more source
ABSTRACT Cartilage is traditionally viewed as a metabolically quiescent tissue that relies primarily on exogenous lipid uptake to meet its energetic and structural demands. However, increasing evidence suggests that chondrocytes exhibit metabolically active behaviors, particularly under aging and pathological conditions.
Shadi Moradi, Anupama Binoy, Shouan Zhu
wiley +1 more source
Post‐Tuberculosis Lung Disease: Clinicopathologic Insights, Diagnosis, Prevention, and Management
A comprehensive review on post‐tuberculosis lung disease (PTLD) addresses the epidemiology, pathogenesis, clinical phenotypes and management, risk factors, prevention and systems approach, and future directions. This review provides standardized definitions, mechanistic insights and biomarkers of PTLD development, and clinical strategies for PTLD ...
Radha Gopalaswamy, Selvakumar Subbian
wiley +1 more source
Nano-Desi Imaging of Eicosanoids in Mouse Kidney Tissue Using Selected Ion Monitoring
Nano-DESI Mass spectrometry imaging of eicosanoids in mouse kidney tissue using selected ion monitoring. Nano-DESI mass spectrometry imaging (MSI) is a technique for label-free spatial and molecular characterization of surfaces and biological samples ...
Huffstutler, Courtney
core
Translational PBPK Modeling and Exposure‐Response Analysis of AT‐RvD1 for Treating Sjögren's Disease
ABSTRACT Sjögren's disease (SD) is an autoimmune condition characterized by chronic inflammation and impaired secretory function of the salivary glands (SG). The proresolving lipid mediator AT‐RvD1 restores SG function in SD‐like mice; however, its tissue pharmacokinetics, exposure‐response relationships, and human dose predictions remain poorly ...
Venkata K. Yellepeddi +3 more
wiley +1 more source
The discovery of prostaglandins over 5 decades ago heralded a new era in the study of mediators or factors involved in physiological and pathophysiological processes.
Morris Karmazyn, Margaret P. Moffat
core +1 more source
UPLC-MS/MS-Based Profiling of Eicosanoids in RAW264.7 Cells Treated with Lipopolysaccharide
While both the pro- and anti-inflammatory effects of several eicosanoids have been widely studied, the degree of inflammation in cells that results from various eicosanoids has yet to be comprehensively studied.
Chun Park +9 more
core +1 more source
Platelet activation and eicosanoid signaling in ovarian cancer: implications for biomarker development. [PDF]
Kirmuć J, Jóźwik M, Kramkowski K.
europepmc +1 more source

