Eicosapentaenoic acid prevents arterial calcification in klotho mutant mice.
BackgroundThe klotho gene was identified as an "aging-suppressor" gene that accelerates arterial calcification when disrupted. Serum and vascular klotho levels are reduced in patients with chronic kidney disease, and the reduced levels are associated ...
Kazufumi Nakamura+12 more
doaj +1 more source
Linguistic mechanism of the evolution of amino acid frequencies and genomic GC content [PDF]
Much information is stored in amino acid composition of protein and base composition of DNA. We simulated the evolution of amino acid frequencies and genomic GC content by a linguistic model. It is showed that the evolution of genetic code determines the evolution of amino acid frequencies and genomic GC content.
arxiv
A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease
Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia+4 more
wiley +1 more source
Genetic Code Table: A note on the three splittings into amino acid classes [PDF]
This note represents the further progress in understanding the determination of the genetic code by Golden mean (Rakocevic, 1998). Three classes of amino acids that follow from this determination (the 7 "golden" amino acids, 7 of their complements, and 6 non-complements) are observed now together with two further possible splittings into 4 x 5 and 5 x ...
arxiv
Diatom triacylglycerol metabolism: from carbon fixation to lipid droplet degradation
ABSTRACT Diatoms are a prominent microalgae family that has attracted interest for its production of molecules of biotechnological interest. Their fatty acid profile is rich in health‐beneficial omega‐3 eicosapentaenoic acid (EPA). Furthermore, under nutrient‐deprived conditions, many diatom species, notably Phaeodactylum tricornutum, Thalassiosira ...
Victor Murison+3 more
wiley +1 more source
Abstract Aims Metabolic‐associated steatotic liver disease (MASLD) is a prevalent chronic liver condition associated with significant morbidity and mortality. Effective pharmacological interventions targeting liver steatosis and fibrosis are essential to improving patient outcomes.
Jiaxin Zhong+3 more
wiley +1 more source
Eicosapentaenoic acid production by Phaeodactylum tricornutum under different culture condition
Phaeodactylum tricornutum UTEX 640 strain of microalgae was screened under different culture conditions for their capacity to produce eicosapentaenoic acid (EPA) the most abundant polyunsaturated fatty acid (PUFA).
J. Kutasi+3 more
doaj +1 more source
Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic acid prevents proteinuria and prolongs survival in NZB x NZW F1 mice. [PDF]
James D. Prickett+2 more
openalex +1 more source
Summary of the clinical practice guideline for the management of urinary stones, third edition
Abstract This third edition of the Japanese Clinical Practice Guidelines for Urinary stones (2023) has been developed under the leadership of the Japanese Urological Association, the Japanese Society of Endourology and Robotics, and the Japanese Society on Urolithiasis Research. This revision adheres to the Minds Manual for Guideline Development (2017)
Katsuhito Miyazawa+22 more
wiley +1 more source