Results 111 to 120 of about 34,751 (135)
Some of the next articles are maybe not open access.
EICOSAPENTAENOIC ACID AND PREVENTION OF THROMBOSIS AND ATHEROSCLEROSIS?
The Lancet, 1978Unlike arachidonic acid (eicosatetraenoic acid, C20:4omega-6, A.A.), eicosapentaenoic acid (C20:5omega-3, E.P.A.) does not induce platelet aggregation in human platelet-rich plasma (P.R.P.), probably because of the formation of thromboxane A3 (T.X.A3) which does not have platelet aggregating properties.
Salvador Moncada +4 more
openaire +3 more sources
Prostaglandins, Leukotrienes and Essential Fatty Acids, 2012
The purpose of this randomized, controlled, parallel group study was to characterize the relationships between dosages of stearidonic acid (SDA) and eicosapentaenoic acid (EPA), and incorporation of EPA into red blood cell (RBC) membranes over time.Healthy subjects (n=131) received capsules with placebo (safflower oil), SDA (0.43, 1.3, 2.6, or 5.2 g/d)
Shawna L. Lemke +9 more
openaire +3 more sources
The purpose of this randomized, controlled, parallel group study was to characterize the relationships between dosages of stearidonic acid (SDA) and eicosapentaenoic acid (EPA), and incorporation of EPA into red blood cell (RBC) membranes over time.Healthy subjects (n=131) received capsules with placebo (safflower oil), SDA (0.43, 1.3, 2.6, or 5.2 g/d)
Shawna L. Lemke +9 more
openaire +3 more sources
European Journal of Pharmaceutics and Biopharmaceutics, 2007
Unexpected enhancement of the topical delivery of eicosapentaenoic acid (EPA) across porcine skin was observed previously when fish oil was co-formulated with ketoprofen. In the current work depth profile analysis was used to probe the epidermal conversion of EPA to its 15-hydroxy metabolite in the presence and absence of ketoprofen.
Christopher Martin Heard +1 more
openaire +3 more sources
Unexpected enhancement of the topical delivery of eicosapentaenoic acid (EPA) across porcine skin was observed previously when fish oil was co-formulated with ketoprofen. In the current work depth profile analysis was used to probe the epidermal conversion of EPA to its 15-hydroxy metabolite in the presence and absence of ketoprofen.
Christopher Martin Heard +1 more
openaire +3 more sources
Effect of eicosapentaenoic acid and docosahexaenoic acid on diabetic osteopenia
Diabetes Research and Clinical Practice, 1995To evaluate the effect of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are polyunsaturated fatty acids, on diabetic osteopenia, we measured the bone fragility in streptozotocin-induced diabetic rats. The fragility of femur was increased in diabetic rats, which was prevented in part by EPA or DHA.
Masakuni Kameyama +8 more
openaire +3 more sources
Health impacts of eicosapentaenoic acid and docosahexaenoic acid.
CABI Reviews, 2013Abstract Long chain omega-3 polyunsaturated fatty acids (LC n -3 PUFA) particularly, eicosapentaenoic acid (EPA, 22: 5 n -3) and docosahexaenoic acid (DHA, 22: 6 n -3) have been reported to reduce the risks of cardiovascular disease (CVD) including myocardial
H. T. Mateos +3 more
openaire +2 more sources
Lipids, 1998
AbstractIt was of interest to investigate the influence of both high doses of eicosapentaenoic acid (EPA) and low doses of 2‐or 3‐methylated EPA on the antioxidant status, as they all cause hypolipidemia, but the dose required is quite different. We fed low doses (250 mg/d/kg body wt) of different EPA derivatives or high doses (1500 mg/d/kg body wt) of
Lise Madsen +3 more
openaire +3 more sources
AbstractIt was of interest to investigate the influence of both high doses of eicosapentaenoic acid (EPA) and low doses of 2‐or 3‐methylated EPA on the antioxidant status, as they all cause hypolipidemia, but the dose required is quite different. We fed low doses (250 mg/d/kg body wt) of different EPA derivatives or high doses (1500 mg/d/kg body wt) of
Lise Madsen +3 more
openaire +3 more sources
Eicosapentaenoic Acid: The Answers Are Not All In
Journal of Clinical Oncology, 2005TO THE EDITOR: Jatoi et al should be congratulated in successfully performing a study comparing eicosapentaenoic acid (EPA) supplements versus megestrol acidate versus both for patients with cancer-associated wasting. The trial involved 421 patients who received EPA supplements twice a day (placebo v megestrol 600 mg per day or 2-gram EPA-containing ...
openaire +2 more sources
Process development of eicosapentaenoic acid production
Biochemical Engineering Journal, 2014Abstract Eicosapentaenoic acid (EPA), a well-known member of omega-3 fatty acids, is considered to have a significant health promoting role in the human body. It is an essential fatty acid as the human body lacks the ability to produce it in vivo and must be supplemented through diet. Microbial EPA represents a potential commercial source.
Alan C. Ward +3 more
openaire +3 more sources
The Absorbability of Free and Esterified Eicosapentaenoic Acid [PDF]
, 1987 Although the antithrombotic and hypolipidemic effects of certain fish oils containing -3 fatty acids are extensively documented, little is known regarding the digestibility, absorption, lipoprotein transport, and chylomicron clearance of lipids containing these acids. Systematic studies have now been conducted to demonstrate the following: the rate and
George V. Vahouny +4 more
openaire +1 more source
EICOSAPENTAENOIC ACID AND PREVENTION OF ATHEROSCLEROSIS
The Lancet, 1978ANGELICO, Francesco, P. Amodeo
openaire +3 more sources