Results 111 to 120 of about 39,070 (273)

Factors impacting the microbial production of eicosapentaenoic acid

open access: yesApplied Microbiology and Biotechnology
Abstract The increasing applications for eicosapentaenoic acid (EPA) and the potential shortfall in supply due to sustainability and contamination issues related with its conventional sources (i.e., fish oils; seafood) led to an extensive search for alternative and sustainable sources, as well as production processes ...
Sérgio Sousa   +2 more
openaire   +4 more sources

Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 136, Issue 5, May 2025.
ABSTRACT Excessive local inflammation is a common mechanism in many cardiovascular diseases (CVDs) such as hypertension, atherosclerosis and aortic aneurysms. In endothelial cells, inflammatory cytokines such as interferons, tumour necrosis factor alpha or interleukins increase oxidative stress and contractile prostanoids and the expression of adhesion
Ana M. Briones   +7 more
wiley   +1 more source

n-3 PUFAs enhance the frequency of murine B-cell subsets and restore the impairment of antibody production to a T-independent antigen in obesity[S]

open access: yesJournal of Lipid Research, 2013
The role of n-3 polyunsaturated fatty acids (PUFA) on in vivo B-cell immunity is unknown. We first investigated how n-3 PUFAs impacted in vivo B-cell phenotypes and antibody production in the absence and presence of antigen compared with a control diet ...
Heather Teague   +5 more
doaj  

Long‐term fasting induces a remodelling of fatty acid composition in erythrocyte membranes

open access: yesEuropean Journal of Clinical Investigation, Volume 55, Issue 5, May 2025.
Abstract Introduction Long‐term fasting (LF) activates an adaptative response to switch metabolic fuels from food glucose to lipids stored in adipose tissues. The increase in free fatty acid (FFA) oxidation during fasting triggers health benefits. We questioned if the changes in lipid metabolism during LF could affect lipids in cell membranes in humans.
Katharina Gewecke   +5 more
wiley   +1 more source

Metabolomics and Microbiomics Perspectives Reveal the Regulatory Pathways of Monaphilone B Derived From Red Yeast Rice on Alcoholic Liver Injury in Mice

open access: yeseFood, Volume 6, Issue 2, April 2025.
Monaphilone B (MB) from red yeast rice mitigates alcoholic liver injury through the regulation of the gut microbiome, liver metabolism, lipid metabolism, and oxidative defense. ABSTRACT Red yeast rice (RYR) has been extensively used as a natural food for thousands of years and still plays an important role in the world food industry. In this study, the
Li Wu   +6 more
wiley   +1 more source

Serum free fatty acids levels not associated with normal tension glaucoma

open access: yesClinical Ophthalmology, 2010
Kenya Yuki, Itaru Kimura, Kazuo TsubotaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, JapanPurpose: To determine the free fatty acid levels in the sera of patients with normal-tension glaucoma and compare it with that of normal ...
Kenya Yuki, Itaru Kimura, Kazuo Tsubota
doaj  

Effects of Long‐Chain n‐3 Fatty Acids Supplementation During Caloric Restriction on Body Composition in Overweight and Obese Adults: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesFood Science &Nutrition, Volume 13, Issue 4, April 2025.
The present meta‐analysis indicates that LCn‐3 PUFA supplementation during caloric restriction does not enhance reductions in body mass and body fat, nor attenuate the decline in fat‐free mass. ABSTRACT This systematic review aimed to determine whether caloric restriction‐induced reduction in body fat and fat‐free mass can be amended by supplementation
Mansour Alblaji   +3 more
wiley   +1 more source

Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol – Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue

open access: yesCurrent Research in Toxicology
On murine N2a cells, 7-ketocholesterol induced an oxiapotophagic mode of cell death characterized by oxidative stress (reactive oxygen species overproduction on whole cells and at the mitochondrial level; lipid peroxidation), apoptosis induction (caspase-
Aline Yammine   +8 more
doaj  

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