Results 111 to 120 of about 71,664 (294)

Plasmalogen as a Bioactive Lipid Drug: From Preclinical Research Challenges to Opportunities in Nanomedicine

open access: yesFASEB BioAdvances, EarlyView.
Plasmalogens are specialized lipids affecting the membrane structure, dynamics, and key cell signaling pathways. They protect cells from oxidative damage. Plasmalogen deficiency is associated with severe diseases. Lipid nanoparticles and nanomedicine offer unexplored therapeutic potential for restoring plasmalogen levels under pathological conditions ...
Yu Wu   +3 more
wiley   +1 more source

A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease

open access: yesActa Ophthalmologica, EarlyView.
Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia   +4 more
wiley   +1 more source

ACSM5 Regulates Ferroptosis in Hepatocellular Carcinoma by Up‐Regulating POR and Modulating Lipid Metabolism

open access: yesCancer Science, EarlyView.
ACSM5 induced ferroptosis in HCC by up‐regulating cytochrome P450 oxidoreductase (POR). The metabolic transformation of linoleic acid to arachidonic acid was also promoted by ACSM5; thereby, the sensitivity to ferroptosis was elevated. ABSTRACT The medium‐chain fatty acyl‐CoA synthetase‐5 (ACSM5) plays a crucial role in the development of some cancers.
Zhengqiang Wu   +8 more
wiley   +1 more source

Eicosapentaenoic acid production by Phaeodactylum tricornutum under different culture condition

open access: yesInternational Journal of Horticultural Science, 2004
Phaeodactylum tricornutum UTEX 640 strain of microalgae was screened under different culture conditions for their capacity to produce eicosapentaenoic acid (EPA) the most abundant polyunsaturated fatty acid (PUFA).
J. Kutasi   +3 more
doaj   +1 more source

Omega-3 fatty acid supplementation accelerates chylomicron triglyceride clearance

open access: yesJournal of Lipid Research, 2003
Omega-3 fatty acids (FAs) reduce postprandial triacylglycerol (TG) concentrations. This study was undertaken to determine whether this effect was due to reduced production or increased clearance of chylomicrons.
Yongsoon Park, William S. Harris
doaj  

Multi‐omic analysis identifies biological processes underlying progressive interstitial lung disease in systemic sclerosis

open access: yesThe FEBS Journal, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease, and lung complications (ILD) are the main cause of death. This study compared SSc patients with and without lung disease to healthy volunteers. We found increased inflammation, specific proteins, and higher triglyceride levels linked to lung disease progression. These findings suggest triglycerides
Selena Bouffette   +16 more
wiley   +1 more source

n-3 PUFAs enhance the frequency of murine B-cell subsets and restore the impairment of antibody production to a T-independent antigen in obesity[S]

open access: yesJournal of Lipid Research, 2013
The role of n-3 polyunsaturated fatty acids (PUFA) on in vivo B-cell immunity is unknown. We first investigated how n-3 PUFAs impacted in vivo B-cell phenotypes and antibody production in the absence and presence of antigen compared with a control diet ...
Heather Teague   +5 more
doaj  

Lipid content and fatty acid dynamics of female muscle, oocytes and larvae of Prochilodus argenteus (Spix & Agassiz, 1829)

open access: yesAquaculture Reports, 2020
This work aimed to determine fatty acid dynamics and lipid composition of female muscle, oocytes, newly hatched larvae (NHL) and first feeding larvae (FFL) of Prochilodus argenteus. Oocytes and NHL had the highest percentages of total lipids.
Edenilce de Fátima Ferreira Martins   +7 more
doaj  

The impact of fish oil fatty-acids on post-prandial vascular reactivity. [PDF]

open access: yes, 2014
Progressive loss of vascular reactivity and increased vascular tone with age are being increasingly recognised as significant cardiovascular disease (CVD) risk factors.
Mcmanus, Sean
core  

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