Results 81 to 90 of about 76,395 (315)

FISHing for the Miracle of Eicosapentaenoic Acid

New England Journal of Medicine, 2019
Bhatt et al. report in the Journal the results of the Reduction of Cardiovascular Events with Icosapent Ethyl–Intervention Trial (REDUCE-IT), in which 8179 high-risk patients who had elevated triglyceride levels and had been receiving statin therapy were randomly assigned to receive 2 g of icosapent ethyl twice daily or placebo containing mineral oil.1
Kastelein, John J. P., Stroes, Erik S. G.   +1 more
openaire   +2 more sources

Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells

Brain Pathology, EarlyView.
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son, Suji Kim, Min‐Tae Jeon, Moonseok Choi, Kyu‐Sung Kim, Suji Lee, Seung‐Yeol Nah, Do‐Geun Kim   +7 more
wiley   +1 more source

Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol – Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue

Current Research in Toxicology
On murine N2a cells, 7-ketocholesterol induced an oxiapotophagic mode of cell death characterized by oxidative stress (reactive oxygen species overproduction on whole cells and at the mitochondrial level; lipid peroxidation), apoptosis induction (caspase-
Aline Yammine, Imen Ghzaiel, Vivien Pires, Amira Zarrouk, Omar Kharoubi, Hélène Greige-Gerges, Lizette Auezova, Gérard Lizard, Anne Vejux   +8 more
doaj   +1 more source

Standard and Specialized Infant Formulas in Europe: Making, Marketing, and Health Outcomes [PDF]

, 2019
Infant formulas are the only suitable substitute for human milk. The most common infant formulas are standard formulas based on cow's milk. In addition, there are formulas for infants showing signs and symptoms of intolerance and for clinical conditions ...
Corsello G, Dipasquale V, Romano C, Serra G   +3 more
core   +1 more source

Protectin D1 and maresin 1 attenuate airway hyperreactivity induced by IL‐13 in human isolated small bronchi

British Journal of Pharmacology, EarlyView.
Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma, Sven‐Erik Dahlén, Craig E. Wheelock, Mikael Adner, Mamdoh Al‐Amerie, Erik Sachs, Kasra Vali Jalali, Leonardo De Maria, Henric Olsson, Jesper Säfholm   +9 more
wiley   +1 more source

Blood serum from individuals with Alzheimer’s disease alters microglial phagocytosis in vitro

Neural Regeneration Research
In Alzheimer’s disease, microglial phagocytosis is engaged in the pathogenesis as it clears abnormal protein accumulations, debris, and apoptotic cells in the early stages of Alzheimer’s disease, but fuels neuroinflammation and accelerates disease ...
Barbara Altendorfer, Rodolphe Poupardin, Sophie Lefèvre-Arbogast, Claudine Manach, Dorrain Y. Low, Mireia Urpi-Sarda, Cristina Andres-Lacueva, Raúl González-Domínguez, Thomas K. Felder, Julia Tevini, Marco Zattoni, Andreas Koller, Reinhold Schmidt, Paul J. Lucassen, Silvie R. Ruigrok, Chiara de Lucia, Andrea Du Preez, Catherine Helmer, Jeanne Neuffer, Cécile Proust-Lima, Aniko Korosi, Cécilia Samieri, Sandrine Thuret, Ludwig Aigner   +23 more
doaj   +1 more source

A transgenic Camelina sativa seed oil effectively replaces fish oil as a dietary source of eicosapentaenoic acid in mice [PDF]

, 2016
Background: Fish currently supplies only 40% of the eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) required to allow all individuals globally to meet the minimum intake recommendation of 500 mg/d.
Betancor, Monica B, Cochard, Marianne, Menoyo, David, Minihane, Anne Marie, Napier, Jonathan A., Rigby, Neil, Ruiz-Lopez, Noemi, Sayanova, Olga, Tejera, Noemi, Tocher, Douglas R., Usher, Sarah, Vauzour, David   +11 more
core   +2 more sources

The Fish Behind Fish Feed: Rethinking Transparency Using DNA Tools

Fish and Fisheries, EarlyView.
ABSTRACT Aquaculture is now the fastest growing food sector and may be a promising solution to increasing seafood demands. Yet, carnivorous aquaculture species such as salmon and seabass continue to rely on fishmeal and fish oil (FMFO), which are derived largely from pelagic fish that are sometimes key to the food security of some coastal nations. This
Marine Cusa, Matilda Binner, Giulia Maiello, Rosalie Dowell, Stefano Mariani   +4 more
wiley   +1 more source

Studies relating to Polyunsaturated Fatty Acid (PUFA) Supplementation and Fertility in Cattle [PDF]

, 2007
End of project reportReproductive inefficiency has a significant impact on the economic performance of both dairy and beef herds, particularly in seasonal calving systems. Nutrition plays a fundamental role in reproduction. Furthermore, there is emerging
Childs, Stuart, Diskin, Michael G., Kenny, David A., Sreenan, J.M.   +3 more
core  

Dietary assessment in Whitehall II: comparison of 7d diet diary and food-frequency questionnaire and validity against biomarkers [PDF]

, 2008
The aim of the present cross-sectional study was to examine the agreement and disagreement between a 7 d diet diary (7DD) and a self-administered machine-readable food-frequency questionnaire (FFQ) asking about diet in the previous year, and to validate ...
Beksinska, Bingham, Black, Brunner, Chan, Chan, Daryth stallone, Eric Brunner, Goldberg, Holland, Holland, Holland, Holland, Holland, Holland, Holland, Maneesh Juneja, Michael Marmot, Paul, Pryer, Schofield, Sheila bingham, Smith   +22 more
core   +1 more source