Full-Length Venom Protein cDNA Sequences from Venom-Derived mRNA: Exploring Compositional Variation and Adaptive Multigene Evolution. [PDF]
PLoS Neglected Tropical Diseases, 2016 Envenomation of humans by snakes is a complex and continuously evolving medical emergency, and treatment is made that much more difficult by the diverse biochemical composition of many venoms.
Cassandra M Modahl, Stephen P Mackessy
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Antivenom Cross-Neutralization of the Venoms of Hydrophis schistosus and Hydrophis curtus, Two Common Sea Snakes in Malaysian Waters [PDF]
, 2015 Sea snake envenomation is a serious occupational hazard in tropical waters. In Malaysia, the beaked sea snake (Hydrophis schistosus, formerly known as Enhydrina schistosa) and the spine-bellied sea snake (Hydrophis curtus, formerly known as Lapemis ...
Choo, Hock Tan +3 more
core +1 more source
Venoms of Rear-Fanged Snakes: New Proteins and Novel Activities
Frontiers in Ecology and Evolution, 2019 Snake venom research has focused on front-fanged venomous snakes because of the high incidence of human morbidity and mortality from envenomations and larger venom yields of these species, while venoms from rear-fanged snakes have been largely neglected.
Cassandra M. Modahl, Stephen P. Mackessy
doaj +1 more source
PLoS Neglected Tropical Diseases, 2023 Snakebite envenoming is a globally important public health issue that has devastating consequences on human health and well-being, with annual mortality rates between 81,000 and 138,000.
Matyas A Bittenbinder +8 more
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Snake antivenom for snake venom induced consumption coagulopathy [PDF]
, 2014 Background Snake venom induced consumption coagulopathy is a major systemic effect of envenoming. Observational studies suggest that antivenom improves outcomes for venom induced consumption coagulopathy in some snakebites and not others. However, the
Allen +18 more
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Protease inhibitors from marine venomous animals and their counterparts in terrestrial venomous animals [PDF]
, 2013 The Kunitz-type protease inhibitors are the best-characterized family of serine protease inhibitors, probably due to their abundance in several organisms.
Mourão, Caroline Barbosa Farias +1 more
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Molecules, 2022 Venom-induced thrombocytopenia (VIT) is one of the most important hemotoxic effects of a snakebite, which is often associated with venom-induced consumptive coagulopathy (VICC).
Cheng Zhang +8 more
doaj +1 more source
Recombinant snakebite antivenoms: A cost-competitive solution to a neglected tropical disease? [PDF]
, 2017 Snakebite envenoming is a major public health burden in tropical parts of the developing world. In sub-Saharan Africa, neglect has led to a scarcity of antivenoms threatening the lives and limbs of snakebite victims.
Andersen, Mikael R +3 more
core +2 more sources
Challenges in diagnosing and treating snakebites in a rural population of Tamil Nadu, India: the views of clinicians [PDF]
, 2017 Snakebites cause death, disability and economic devastation to their victims, people who live almost exclusively in rural areas. Annually an estimated two million venomous bites cause as many as 100,000 deaths worldwide as well as hundreds of thousands ...
Bicknell, Andrew B. +6 more
core +1 more source
Effect of Australian elapid venoms on blood coagulation: Australian Snakebite Project (ASP-17)
Toxicon, 2012 Snake venoms contain toxins that activate the coagulation network and cause venom-induced consumption coagulopathy. A previously developed mathematical model of the coagulation network was refined and used to describe and predict the time course of changes in the coagulation factors following envenomation by Brown snake (Pseudonaja spp.), Tiger snake ...
Abhishek Gulati +2 more
openalex +3 more sources