Results 41 to 50 of about 1,625 (162)

Inflammation induced by snake venoms optimizes envenomation

The Journal of Physiology, Volume 604, Issue 14, Page 5831-5852, 15 July 2026.
Abstract figure legend Schematic illustrating mechanisms underlying direct vascular absorption and subsequent movement of venom toxins into the tissues consequent to snakebite. A, snakebite into prey deposits venom toxins into the tissue interstitium, with the venom then causing acute inflammation primarily in venules.
Dirk F. van Helden, Neil Spratt, Peter J. Dosen, Sally A. McFadden, John Holdsworth, Daniel J Beard, Kirsten Coupland, Phillip Jobling, Todd A. Hardy, Derek R. Laver   +9 more
wiley   +1 more source

Discovery of Neuroprotective Venom‐Derived Candidates From Naja Mandalayensis in mHippoE‐18 Cells Via Fractionation and Proteomic Mapping

Chemistry &Biodiversity, Volume 23, Issue 5, May 2026.
Venom‐derived peptide diversity from Naja mandalayensis reveals bioactive subfractions capable of modulating neuronal oxidative stress responses. Integration of RP‐HPLC fractionation and proteomics identifies toxin families associated with improved mitochondrial function and cellular integrity in mHippoE‐18 cells, supporting venoms as a platform for ...
Brenda Rufino da Silva, Lais Campelo Mendes, Emidio Beraldo‐Neto, Carlos Alberto‐Silva   +3 more
wiley   +1 more source

Hepatotoxic effect of elapid venom-a rare manifestation: Case report. [PDF]

J Family Med Prim Care
ABSTRACT Snake bite is a neglected tropical disease affecting millions of people across the globe. The highest burden exists in South East Asia and Sub-Saharan Africa. Around 45900 deaths could be attributed to snake bites in India with 25% of these deaths occurring in children between age group of 5–14 years.
Chaudhuri PK, Azam N, Madhur A, Singh J, Kumar R, Prasad A, Sarkar P.   +6 more
europepmc   +4 more sources

Engineered nanoparticles bind elapid snake venom toxins and inhibit venom-induced dermonecrosis

PLOS Neglected Tropical Diseases, 2018
Envenomings by snakebites constitute a serious and challenging global health issue. The mainstay in the therapy of snakebite envenomings is the parenteral administration of animal-derived antivenoms. Significantly, antivenoms are only partially effective in the control of local tissue damage. A novel approach to mitigate the progression of local tissue
Jeffrey O’Brien, Shih-Hui Lee, José María Gutiérrez, Kenneth J. Shea   +3 more
openaire   +6 more sources

Molecular Evolution and Phylogeny of Elapid Snake Venom Three-Finger Toxins [PDF]

Journal of Molecular Evolution, 2003
Animal venom components are of considerable interest to researchers across a wide variety of disciplines, including molecular biology, biochemistry, medicine, and evolutionary genetics. The three-finger family of snake venom peptides is a particularly interesting and biochemically complex group of venom peptides, because they are encoded by a large ...
Fry, B.G., Wüster, W., Kini, R.M., Brusic, V., Khan, A., Venkataraman, D., Rooney, A.P.   +6 more
openaire   +5 more sources

CROSS NEUTRALIZATION OF SOME SNAKE VENOMS FROM AFRICA AND MIDDLE EAST BY VACSERA POLYVALENT SNAKE ANTISERA [PDF]

Journal of the Egyptian Society of Parasitology
An extensive study of neutralization of lethality of two species of elapid, seven species ofgenus Viper, and two species of Macrovipera by VACSERA polyvalent snake antisera.The results showed that polyvalent snake venom antisera prepared by injecting ...
ABIR ELFIKY, SHERIF ELFEEL
doaj   +1 more source

Occurrence and evolution of cannibal behaviour in extant snakes

Biological Reviews, Volume 101, Issue 2, Page 644-664, April 2026.
ABSTRACT Extant snakes (Serpentes) are a highly diverse group of squamate reptiles, which have independently evolved key morphological adaptations to consume a large variety of vertebrate and invertebrate prey. While these predator–prey interactions have been widely addressed by several studies, little is known regarding the occurrence of cannibal ...
Bruna B. Falcão, Vinícius A. São Pedro, Omar M. Entiauspe‐Neto   +2 more
wiley   +1 more source

Heterologous expression, protein folding and antibody recognition of a neurotoxin from the Mexican coral snake Micrurus laticorallis

Journal of Venomous Animals and Toxins including Tropical Diseases, 2016
Background The cysteine-rich neurotoxins from elapid venoms are primarily responsible for human and animal envenomation; however, their low concentration in the venom may hamper the production of efficient elapid antivenoms.
Herlinda Clement, Vianey Flores, Guillermo De la Rosa, Fernando Zamudio, Alejandro Alagon, Gerardo Corzo   +5 more
doaj   +1 more source

Platelet Desialylation Is a Novel Mechanism and Therapeutic Target in Daboia siamensis and Agkistrodon halys Envenomation-Induced Thrombocytopenia

Molecules, 2022
Venom-induced thrombocytopenia (VIT) is one of the most important hemotoxic effects of a snakebite, which is often associated with venom-induced consumptive coagulopathy (VICC).
Cheng Zhang, Zhanfeng Zhang, Enyu Liang, Yunlong Gao, Hui Li, Fangfang Xu, Weiye Chen, Ming Liu, Xianzhang Huang   +8 more
doaj   +1 more source

Polymeric Nanoparticles for the Diagnosis and Treatment of Snakebite

Macromolecular Chemistry and Physics, Volume 227, Issue 1, 15 January 2026.
Snakebite envenomation affects between 1.8 and 5.5 million people annually, many of whom suffer disabilities or even death. Current antivenoms are composed of plasma‐derived antibodies. However, there remains an underexplored opportunity to utilise polymer‐based nanoparticles.
Neil Prabhakar, Thomas Oliver, Alexander N. Baker   +2 more
wiley   +1 more source