Results 21 to 30 of about 1,625 (162)
Cross neutralization of Afro-Asian cobra and Asian krait venoms by a Thai polyvalent snake antivenom (Neuro Polyvalent Snake Antivenom). [PDF]
PLoS Neglected Tropical Diseases, 2012 BACKGROUND: Snake envenomation is a serious public health threat in the rural areas of Asian and African countries. To date, the only proven treatment for snake envenomation is antivenom therapy.
Poh Kuan Leong +5 more
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Toxins, 2021 Some Australian elapids possess potently procoagulant coagulotoxic venoms which activate the zymogen prothrombin into the functional enzyme thrombin. Although the activity of Australian elapid prothrombin-activators has been heavily investigated with ...
Nicholas J. Youngman +2 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2016 Snakebite envenomation is a serious medical problem in many tropical developing countries and was considered by WHO as a neglected tropical disease.
Kavi Ratanabanangkoon +8 more
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Investigating Toxin Diversity and Abundance in Snake Venom Proteomes
Frontiers in Pharmacology, 2022 Understanding snake venom proteomes is becoming increasingly important to understand snake venom biology, evolution and especially clinical effects of venoms and approaches to antivenom development.
Theo Tasoulis +2 more
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Elapid venom toxins: multiple recruitments of ancient scaffolds [PDF]
European Journal of Biochemistry, 1999 Nigroxins A and B, two myotoxic phospholipases A2 (PLA2s) from the venom of the American elapid Micrurus nigrocinctus, belong to a new PLA2 subclass. Their primary structures were established and compared with those of PLA2s that have already been studied with respect to myotoxic activity.
Alape Girón, Alberto +7 more
openaire +4 more sources
Polyamines as Snake Toxins and Their Probable Pharmacological Functions in Envenomation
Toxins, 2016 While decades of research have focused on snake venom proteins, far less attention has been paid to small organic venom constituents. Using mostly pooled samples, we surveyed 31 venoms (six elapid, six viperid, and 19 crotalid) for spermine, spermidine ...
Steven D. Aird +3 more
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Toxins, 2014 Elapid snake venom is a highly valuable, but till now mainly unexplored, source of pharmacologically important peptides. We analyzed the peptide fractions with molecular masses up to 10 kDa of two elapid snake venoms—that of the African cobra, N.
Aisha Munawar +10 more
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Comparative Analysis of Prothrombin Activators from the Venom of Australian Elapids [PDF]
Molecular Biology and Evolution, 2005 A key component of the venom of many Australian snakes belonging to the elapid family is a toxin that is structurally and functionally similar to that of the mammalian prothrombinase complex. In mammals, this complex is responsible for the cleavage of prothrombin to thrombin and is composed of factor Xa in association with its cofactors calcium ...
St. Pierre, Liam +6 more
openaire +5 more sources
Two pathways for venom toxin entry consequent to injection of an Australian elapid snake venom [PDF]
Scientific Reports, 2019 AbstractHere we test and refute the hypothesis that venom toxins from an Australian elapid, the Eastern Brown snake (Pseudonaja textilis, PTx), solely require lymphatic transport to enter the circulation. Studies were made using anaesthetised non-recovery rats in which a marker dye (India ink) or highly potent PTx venom was injected into the hind paw ...
Dirk F. van Helden +3 more
openaire +2 more sources
Coral snake venoms: mode of action and pathophysiology of experimental envenomation
Revista do Instituto de Medicina Tropical de São Paulo, 1987 Coral snakes, the New World Elapidae, are included in the genera Micniroides and Micrurus. The genus Mlcrurus comprises nearly all coral snake species and those which are responsible for human snake-bite accidents.
Oswald Vital Brazil
doaj +1 more source