Investigating Toxin Diversity and Abundance in Snake Venom Proteomes
Frontiers in Pharmacology, 2022 Understanding snake venom proteomes is becoming increasingly important to understand snake venom biology, evolution and especially clinical effects of venoms and approaches to antivenom development.
Theo Tasoulis +2 more
doaj +1 more source
Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]
, 2011 Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Balmer, L. +5 more
core +2 more sources
Toxinology of Venoms from Five Australian Lesser Known Elapid Snakes [PDF]
Basic & Clinical Pharmacology & Toxicology, 2012 AbstractResearch into Australian elapid venoms has mainly focused on the seven genera of greatest clinical significance: Acanthophis, Hoplocephalus, Notechis, Oxyuranus, Pseudechis, Pseudonaja and Tropidechis. However, even small species represent a potential for causing severe clinical envenoming.
Pycroft, Kyle +6 more
openaire +3 more sources
Toxins, 2014 Elapid snake venom is a highly valuable, but till now mainly unexplored, source of pharmacologically important peptides. We analyzed the peptide fractions with molecular masses up to 10 kDa of two elapid snake venoms—that of the African cobra, N.
Aisha Munawar +10 more
doaj +1 more source
Stabilising the Integrity of Snake Venom mRNA Stored under Tropical Field Conditions Expands Research Horizons. [PDF]
, 2016 BACKGROUND Snake venoms contain many proteinaceous toxins that can cause severe pathology and mortality in snakebite victims. Interestingly, mRNA encoding such toxins can be recovered directly from venom, although yields are low and quality is unknown ...
Logan, Rhiannon
core +1 more source
The urgent need to develop novel strategies for the diagnosis and treatment of snakebites [PDF]
, 2019 Snakebite envenoming (SBE) is a priority neglected tropical disease, which kills over one hundred thousand people per year. However, many millions of survivors also suffer through disabilities and long-term health consequences.
Aagaard-Hansen +39 more
core +1 more source
Antivenom Cross-Neutralization of the Venoms of Hydrophis schistosus and Hydrophis curtus, Two Common Sea Snakes in Malaysian Waters [PDF]
, 2015 Sea snake envenomation is a serious occupational hazard in tropical waters. In Malaysia, the beaked sea snake (Hydrophis schistosus, formerly known as Enhydrina schistosa) and the spine-bellied sea snake (Hydrophis curtus, formerly known as Lapemis ...
Choo, Hock Tan +3 more
core +1 more source
Coral snake venoms: mode of action and pathophysiology of experimental envenomation
Revista do Instituto de Medicina Tropical de São Paulo, 1987 Coral snakes, the New World Elapidae, are included in the genera Micniroides and Micrurus. The genus Mlcrurus comprises nearly all coral snake species and those which are responsible for human snake-bite accidents.
Oswald Vital Brazil
doaj +1 more source
Scientific Reports, 2022 Antivenom is currently the first-choice treatment for snakebite envenoming. However, only a low proportion of antivenom immunoglobulins are specific to venom toxins, resulting in poor dose efficacy and potency.
Stefanie K. Menzies +9 more
doaj +1 more source
Recombinant snakebite antivenoms: A cost-competitive solution to a neglected tropical disease? [PDF]
, 2017 Snakebite envenoming is a major public health burden in tropical parts of the developing world. In sub-Saharan Africa, neglect has led to a scarcity of antivenoms threatening the lives and limbs of snakebite victims.
Andersen, Mikael R +3 more
core +5 more sources