Results 11 to 20 of about 2,588 (206)

A Quest for a Universal Plasma-Derived Antivenom Against All Elapid Neurotoxic Snake Venoms

open access: yesFrontiers in Immunology, 2021
This review describes the research aimed at the development of universal antivenom against elapid neurotoxic snake venoms. The antivenoms produced in Thailand in the 1980s were of low potency, especially against the elapid venoms.
Kavi Ratanabanangkoon
doaj   +3 more sources

Pro-inflammatory activities in elapid snake venoms [PDF]

open access: yesToxicon, 1994
Snake venoms from the genera Micrurus (M. ibiboboca and M. spixii) and Naja (N. naja, N. melanoleuca and N. nigricollis) were analysed, using biological and immunochemical methods, to detect pro‐inflammatory activities, cobra venom factor (COF), proteolytic enzymes, thrombin‐like substances, haemorrhagic and oedema‐producing substances.
D V, Tambourgi   +5 more
openaire   +4 more sources

Hepatotoxic effect of elapid venom-a rare manifestation: Case report. [PDF]

open access: yesJ Family Med Prim Care
ABSTRACT Snake bite is a neglected tropical disease affecting millions of people across the globe. The highest burden exists in South East Asia and Sub-Saharan Africa. Around 45900 deaths could be attributed to snake bites in India with 25% of these deaths occurring in children between age group of 5–14 years.
Chaudhuri PK   +6 more
europepmc   +3 more sources

Electrical Cell Impedance Sensing (ECIS): Feasibility of a Novel In Vitro Approach to Studying Venom Toxicity and Potential Therapeutics [PDF]

open access: yesToxins
Snakebite envenoming is often discussed in terms of lethality and limb loss, but local tissue injury and coagulotoxic effects of venom are significantly more common acute manifestations of snakebite envenoming (SBE).
Abhinandan Choudhury   +7 more
doaj   +2 more sources

Snake Venom Protease Detection and Inhibition in Serum. [PDF]

open access: yesChemMedChem
A fluorescence assay enables sensitive detection of the activities of snake venom metalloproteases (SVMP) and serine proteases (SVSP) from viper venoms in buffer and serum. In combination with effective low‐molecular‐weight inhibitors such as ilomastat and nafamostat, this approach offers new prospects for the rapid diagnosis and adjunctive therapy of ...
Riedel M, Kersten C.
europepmc   +2 more sources

Snake Venomics and Antivenomics of Bothrops diporus, a Medically Important Pitviper in Northeastern Argentina [PDF]

open access: yes, 2015
Snake species within genus Bothrops are responsible for more than 80% of the snakebites occurring in South America. The species that cause most envenomings in Argentina, B.
Calvete, Juan J.   +3 more
core   +12 more sources

Application of an Extracellular Matrix-Mimicking Fluorescent Polymer for the Detection of Proteolytic Venom Toxins

open access: yesToxins, 2023
The cytotoxicity caused by snake venoms is a serious medical problem that greatly contributes to the morbidity observed in snakebite patients. The cytotoxic components found in snake venoms belong to a variety of toxin classes and may cause cytotoxic ...
Eric Wachtel   +8 more
doaj   +1 more source

Cytotoxin antibody-based colourimetric sensor for field-level differential detection of elapid among big four snake venom.

open access: yesPLoS Neglected Tropical Diseases, 2021
Development of a rapid, on-site detection tool for snakebite is highly sought after, owing to its clinically and forensically relevant medicolegal significance.
Sherin Kaul   +6 more
doaj   +1 more source

Polyvalent Snake Antivenoms: Production Strategy and Their Therapeutic Benefits

open access: yesToxins, 2023
Snake envenomation remains an important yet neglected medical problem in many countries, with around five million people affected, and over a hundred thousand deaths annually. Plasma-derived antivenoms are the main therapeutic agent available. Monovalent
Kavi Ratanabanangkoon
doaj   +1 more source

A Combined Bioassay and Nanofractionation Approach to Investigate the Anticoagulant Toxins of Mamba and Cobra Venoms and Their Inhibition by Varespladib

open access: yesToxins, 2022
Envenomation by elapid snakes primarily results in neurotoxic symptoms and, consequently, are the primary focus of therapeutic research concerning such venoms. However, mounting evidence suggests these venoms can additionally cause coagulopathic symptoms,
Arif Arrahman   +7 more
doaj   +1 more source

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