Results 51 to 60 of about 2,588 (206)
, 2017 Snakebite envenoming is a neglected tropical disease that kills >100,000 people and maims >400,000 people every year. Impoverished populations living in the rural tropics are particularly vulnerable; snakebite envenoming perpetuates the cycle of poverty.
Calvete, Juan J +5 more
core +3 more sources
Comparative Analysis of Prothrombin Activators from the Venom of Australian Elapids [PDF]
Molecular Biology and Evolution, 2005 A key component of the venom of many Australian snakes belonging to the elapid family is a toxin that is structurally and functionally similar to that of the mammalian prothrombinase complex. In mammals, this complex is responsible for the cleavage of prothrombin to thrombin and is composed of factor Xa in association with its cofactors calcium ...
St. Pierre, Liam +6 more
openaire +3 more sources
Haemotixic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise [PDF]
, 2017 Snake venoms are mixtures of numerous proteinacious components that exert diverse functional activities on a variety of physiological targets. Because the toxic constituents found in venom vary from species to species, snakebite victims can present with ...
Abubakar +97 more
core +4 more sources
Venoms of Rear-Fanged Snakes: New Proteins and Novel Activities
Frontiers in Ecology and Evolution, 2019 Snake venom research has focused on front-fanged venomous snakes because of the high incidence of human morbidity and mortality from envenomations and larger venom yields of these species, while venoms from rear-fanged snakes have been largely neglected.
Cassandra M. Modahl, Stephen P. Mackessy
doaj +1 more source
PLoS Neglected Tropical Diseases, 2023 Snakebite envenoming is a globally important public health issue that has devastating consequences on human health and well-being, with annual mortality rates between 81,000 and 138,000.
Matyas A Bittenbinder +8 more
doaj +1 more source
Crotalus atrox venom preconditioning increases plasma fibrinogen and reduces perioperative hemorrhage in a rat model of surgical brain injury. [PDF]
, 2017 Perioperative bleeding is a potentially devastating complication in neurosurgical patients, and plasma fibrinogen concentration has been identified as a potential modifiable risk factor for perioperative bleeding.
Applegate, Richard +12 more
core +1 more source
Acta Crystallographica Section F, Volume 82, Issue 5, Page 150-159, May 2026.The crystal structure of an Asp49 phospholipase A2 from L. muta is reported, revealing a tetrameric assembly, catalytic conservation and a polarized electrostatic surface potentially linked to membrane targeting.Snake‐venom phospholipases A2 (PLA2s) are small, structurally conserved enzymes that contribute significantly to the pathophysiology of ...
Noelia Erika Neyra Chama +9 more
wiley +1 more source
Vintage venoms: proteomic and pharmacological stability of snake venoms stored for up to eight decades [PDF]
, 2014 For over a century, venom samples from wild snakes have been collected and stored around the world. However, the quality of storage conditions for "vintage" venoms has rarely been assessed.
Addis +63 more
core +1 more source
Occurrence and evolution of cannibal behaviour in extant snakes
Biological Reviews, Volume 101, Issue 2, Page 644-664, April 2026.ABSTRACT Extant snakes (Serpentes) are a highly diverse group of squamate reptiles, which have independently evolved key morphological adaptations to consume a large variety of vertebrate and invertebrate prey. While these predator–prey interactions have been widely addressed by several studies, little is known regarding the occurrence of cannibal ...
Bruna B. Falcão +2 more
wiley +1 more source
Toxins, 2022 The Australasian region is home to the most diverse elapid snake radiation on the planet (Hydrophiinae). Many of these snakes have evolved into unique ecomorphs compared to elapids on other continents; however, their venom compositions are poorly known.
Theo Tasoulis +5 more
openaire +4 more sources