Results 61 to 70 of about 1,625 (162)

One Bite, Two Severe Envenomations Despite Antivenom Therapy: A Case Report

Clinical Case Reports, Volume 13, Issue 7, July 2025.
ABSTRACT This case report describes a 12‐year‐old child who was bitten by a cobra and developed two distinct systemic neurotoxic episodes, 19 h apart, along with severe local envenoming, despite receiving appropriate treatment with antivenom and making a full recovery.
Ravi Shukla, Puja Shrestha, Binod Khanal, Shraddha Paudyal, Bipal Regmi   +4 more
wiley   +1 more source

An N‐Terminally Elongated Peptide From Conus rolani Defines a New Class of Ribbon α‐Conotoxins Targeting Muscle nAChRs

The FASEB Journal, Volume 39, Issue 12, 30 June 2025.
α‐RoIA is an atypical N‐terminally elongated conotoxin discovered in Conus rolani. N‐terminal elongation delays activity in vivo; however, this elongation must be removed to block muscle nicotinic acetylcholine receptors (nAChRs). Only the truncated ribbon isoform of RoIA blocks muscle nAChRs.
Matías L. Giglio, Paula Flórez‐Salcedo, Layla Azam, Maren Watkins, Thomas Lund Koch, Erianna Basgall‐De la Rosa, Adam D. Douglass, J. Michael McIntosh, Baldomero M. Olivera, Joanna Gajewiak   +9 more
wiley   +1 more source

Early cardiovascular collapse after envenoming by snakes in Australia, 2005–2020: an observational study (ASP‐31)

Medical Journal of Australia, Volume 222, Issue 6, Page 313-317, April 2025.
Abstract Objectives To investigate the frequency, timing, and characteristics of cardiovascular collapse after snakebite in Australia, and the complications of collapse following envenoming. Study design Observational study; analysis of prospectively collected demographic and clinical data.
Geoffrey K Isbister, Katherine Z Isoardi, Angela L Chiew, Shane Jenkins, Nicholas A Buckley   +4 more
wiley   +1 more source

Parallel in vitro ion channel and in vivo zebrafish assaying of elapid snake venoms following chromatographic separation of toxin components

SLAS Discovery
Snake venoms are complex bioactive mixtures designed to paralyse, kill, or digest prey. These venoms are of pharmacological interest due to their ability to modulate molecular targets such as ion channels and receptors with high specificity and potency ...
Arif Arrahman, Haifeng Xu, Muzaffar A. Khan, Tijmen S. Bos, Julien Slagboom, Guus C. van der Velden, Ulrike Nehrdich, Nicholas R. Casewell, Michael K. Richardson, Christian Tudorache, Fernanda C. Cardoso, Jeroen Kool   +11 more
doaj   +1 more source

Ritualistic Male–Male Combat of the Northern King Cobra (Ophiophagus hannah) in Thailand

Ecology and Evolution, Volume 15, Issue 4, April 2025.
Following the recent taxonomic split of the king cobra complex, it is important to provide new information and context to behaviors and natural history linked to each new species. We therefore provide detailed observations of ritualistic male–male combat of the newly described northern king cobra (Ophiophagus hannah).
David Roman Bontrager, Jack T. Christie, Andrew J. Pierce, Taksin Artchawakom, Surachit Waengsothorn, Max Dolton Jones   +5 more
wiley   +1 more source

Review of osteoderm function and future research directions

Journal of Zoology, Volume 325, Issue 1, Page 1-24, January 2025.
Osteoderms are bone plates in the skin that occur in virtually all major tetrapod clades. Much has been speculated about their function, but many questions remain unanswered. This review provides an overview of the current state of knowledge and future research directions in this field.
R. Ebel, A. Herrel, T. M. Scheyer, J. S. Keogh   +3 more
wiley   +1 more source

A Review and Database of Snake Venom Proteomes

Toxins, 2017
Advances in the last decade combining transcriptomics with established proteomics methods have made possible rapid identification and quantification of protein families in snake venoms.
Theo Tasoulis, Geoffrey K. Isbister
doaj   +1 more source

Neutralization of the Principal Toxins from the Venoms of Thai Naja kaouthia and Malaysian Hydrophis schistosus: Insights into Toxin-Specific Neutralization by Two Different Antivenoms

Toxins, 2016
Antivenom neutralization against cobra venoms is generally low in potency, presumably due to poor toxin-specific immunoreactivity. This study aimed to investigate the effectiveness of two elapid antivenoms to neutralize the principal toxins purified from
Kae Yi Tan, Choo Hock Tan, Shin Yee Fung, Nget Hong Tan   +3 more
doaj   +1 more source

A Documented Case of Ichthyophagy in the Malayan Krait (Bungarus candidus) and Its Implications for Toxinology

Diversity
Snakebite is a neglected tropical disease, and the high potency of snake venoms has been evolutionary refined for trophic interactions. Hence, understanding the feeding ecology of snakes is a major element needed to meaningfully interpret toxinological ...
Tim Lüddecke
doaj   +1 more source

Atrase A, a P-III class metalloproteinase purified from cobra venom, exhibits potent anticoagulant activity by inhibiting coagulation pathway and activating the fibrinolytic system

Heliyon
Snake venoms, comprising a complex array of protein-rich components, an important part of which are snake venom metalloproteinases (SVMPs). These SVMPs, which are predominantly isolated from viperid venoms, are integral to the pathology of snakebites ...
Xin-Jie Zhong, Cai-E Wang, Ya-Nan Li, Qi-Yun Zhang, Qian-Yun Sun   +4 more
doaj   +1 more source