Results 31 to 40 of about 5,650,951 (272)

The Variable Strength of Electrical Synapses [PDF]

open access: yesNeuron, 2016
In contrast to chemical synapses, less is known regarding the determinants of the strength of electrical synapses. New evidence from Szoboszlay et al. (2016) shows that the number of gap junctions is the dominant factor underlying the strength of electrical coupling between cerebellar interneurons.
openaire   +2 more sources

Dendritic spines as chemical and electrical compartments : a two-photon imaging study in the hippocampus of the rat [PDF]

open access: yes, 2008
Most excitatory synapses are located on small dendritic protrusions called spines. So far, the function of dendritic spines is not fully understood. Imaging experiments have shown that spines can compartmentalize second messengers such as Ca2+.
Müller-Grunditz, Åsa
core   +1 more source

Electrical synapse structure requires distinct isoforms of a postsynaptic scaffold.

open access: yesPLoS Genetics, 2023
Electrical synapses are neuronal gap junction (GJ) channels associated with a macromolecular complex called the electrical synapse density (ESD), which regulates development and dynamically modifies electrical transmission.
Jennifer Carlisle Michel   +21 more
doaj   +1 more source

Posthatching development of synapses in the neuropil of nucleus rotundus of the zebra finch: a quantitative electron microscopic study [PDF]

open access: yes, 1986
Nixdorf B, Bischof H-J. Posthatching development of synapses in the neuropil of nucleus rotundus of the zebra finch: a quantitative electron microscopic study. The Journal of Comparative Neurology.
Nixdorf, Barbara   +3 more
core   +1 more source

Downregulation of Neuronal and Dendritic Connexin36-Made Electrical Synapses Without Glutamatergic Axon Terminals in Spinal Anterior Horn Cells From the Early Stage of Amyotrophic Lateral Sclerosis

open access: yesFrontiers in Neuroscience, 2018
Connexin36 (Cx36) forms gap junctions between neurons, which are called electrical synapses, enabling adjacent neurons to communicate directly. The participation of chemical synapses in neurodegeneration in amyotrophic lateral sclerosis (ALS) has long ...
Yuko Kobayakawa   +8 more
doaj   +1 more source

The ever-changing electrical synapse [PDF]

open access: yesCurrent Opinion in Neurobiology, 2014
A wealth of research has revealed that electrical synapses in the central nervous system exhibit a high degree of plasticity. Several recent studies, particularly in the retina and inferior olive, highlight this plasticity. Three classes of mechanisms can alter electrical coupling over time courses ranging from milliseconds to days. Changes of membrane
openaire   +2 more sources

Adenosine A1 receptor activation mediates the developmental shift at layer 5 pyramidal cell synapses and is a determinant of mature synaptic strength [PDF]

open access: yes, 2013
During the first postnatal month glutamatergic synapses between layer 5 pyramidal cells in the rodent neocortex switch from an immature state exhibiting high probability of neurotransmitter release, large unitary amplitude and synaptic depression to a ...
Richardson, Magnus J. E.   +2 more
core   +1 more source

Determining the neurotransmitter concentration profile at active synapses [PDF]

open access: yes, 2009
Establishing the temporal and concentration profiles of neurotransmitters during synaptic release is an essential step towards understanding the basic properties of inter-neuronal communication in the central nervous system.
Beato, M.   +3 more
core   +1 more source

Hemichannel composition and electrical synaptic transmission: molecular diversity and its implications for electrical rectification.

open access: yesFrontiers in Cellular Neuroscience, 2014
Unapposed hemichannels formed by oligomerized hexamers of gap junction proteins are now known to be involved in various cellular processes under both physiological and pathological conditions. On the other hand, less is known regarding how disparities in
Nicolas ePalacios Prado   +5 more
doaj   +1 more source

High sensitivity and wide response range artificial synapse based on polyimide with embedded graphene quantum dots

open access: yesScientific Reports, 2023
Artificial electronic synapses are commonly used to simulate biological synapses to realize various learning functions, regarded as one of the key technologies in the next generation of neurological computation.
Lijie Kou   +6 more
doaj   +1 more source

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