Results 81 to 90 of about 8,091 (214)
Defects in very long chain fatty acid synthesis enhance alpha-synuclein toxicity in a yeast model of Parkinson's disease. [PDF]
PLoS ONE, 2011 We identified three S. cerevisiae lipid elongase null mutants (elo1Δ, elo2Δ, and elo3Δ) that enhance the toxicity of alpha-synuclein (α-syn). These elongases function in the endoplasmic reticulum (ER) to catalyze the elongation of medium chain fatty ...
Yong Joo Lee +4 more
doaj +1 more source
Fendioxypyracil, a new and systemic PPO‐inhibiting herbicide for X‐spectrum weed control
Pest Management Science, Volume 82, Issue 7, Page 6794-6807, July 2026.This graphical abstract presents the discovery and synthesis of PPO herbicide structures with a central pyridine core, showing molecular conformations, dose–response inhibition curves for PPO1 and PPO2, and comparative weed and grass control efficacy of fendioxypyracil versus other herbicides in greenhouse and field trials.
Tobias Seiser +8 more
wiley +1 more source
, 2006 Bryophyte Marchantia polymorpha L. produces C22 very-long-chain polyunsaturated fatty acid (VLCPUFA). Thus far, no enzyme that mediates elongation of C20 VLCPUFAs has been identified in land plants.
Sakai, Yasuyoshi +5 more
core +1 more source
Animal Genetics, Volume 57, Issue 3, June 2026.ABSTRACT The intramuscular fat (IMF) content is an important indicator of meat quality, affecting the sensory properties of meat. IMF is a complex trait with polygenic nature. This research aimed to identify differentially expressed (DE) genes and key transcription factors (TFs) associated with IMF deposition in the liver of two rabbit lines ...
Jesús Valdés‐Hernández +4 more
wiley +1 more source
Animal, 2012 Studies suggested that in human adults, linoleic acid (LA) inhibits the biosynthesis of n-3 long-chain polyunsaturated fatty acids (LC-PUFA), but their effects in growing subjects are largely unknown.
W. Smink +4 more
doaj +1 more source
Agrosystems, Geosciences &Environment, Volume 9, Issue 2, June 2026.Abstract Barnyardgrass [Echinochloa crus‐galli (L.) P. Beauv.] is the most problematic weed of delayed‐flooded rice (Oryza sativa L.) systems in the mid‐southern United States. Recent findings suggest that acetochlor can achieve effective barnyardgrass control in rice, but rice injury can occur with rainfall soon after application.
Samuel C. Noe +5 more
wiley +1 more source
Site‐directed mutagenesis of a fatty acid elongase ELO‐like condensing enzyme [PDF]
FEBS Letters, 2013 The condensation step of fatty acid elongation is the addition of a C2 unit from malonyl‐CoA to an acyl primer catalyzed by one of two families of enzymes, the 3‐ketoacyl‐CoA synthases and the ELO‐like condensing enzymes. 3‐Ketoacyl‐CoA synthases use a Claisen‐like reaction mechanism while the mechanism of the ELO‐catalyzed condensation reaction is ...
Hernandez-Buquer, Selene +1 more
openaire +2 more sources
, 2023 Colorectal cancer (CRC) cells show some alterations in lipid metabolism, including an increased fatty acid elongation. This study was focused on investigating the effect of a small interfering RNA (siRNA)-mediated decrease in fatty acid elongation on CRC
Aleksandra Czumaj +4 more
core +1 more source
Construction of DGLA producing cell factory by genetic modification of Mucor circinelloides
Microbial Cell Factories, 2019 Background Dihomo-gamma linolenic acid (DGLA, 20:3, n-6) is the elongated product of Gamma linolenic acid (GLA, 18:3, n-6) catalyzed by the enzyme delta-6 elongase (D6E) or gamma linolenic acid elongase (GLELO).
Md. Ahsanul Kabir Khan +6 more
doaj +1 more source
Elongase reactions as control points in long-chain polyunsaturated fatty acid synthesis. [PDF]
PLoS ONE, 2011 BACKGROUND: Δ6-Desaturase (Fads2) is widely regarded as rate-limiting in the conversion of dietary α-linolenic acid (18:3n-3; ALA) to the long-chain omega-3 polyunsaturated fatty acid docosahexaenoic acid (22:6n-3; DHA).
Melissa K Gregory +4 more
doaj +1 more source