Results 81 to 90 of about 8,658 (206)

Elongase reactions as control points in long-chain polyunsaturated fatty acid synthesis. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Δ6-Desaturase (Fads2) is widely regarded as rate-limiting in the conversion of dietary α-linolenic acid (18:3n-3; ALA) to the long-chain omega-3 polyunsaturated fatty acid docosahexaenoic acid (22:6n-3; DHA).
Melissa K Gregory   +4 more
doaj   +1 more source

Dietary Intervention With Lutein, Docosahexaenoic Acid, and Choline During Early Development Improves Recognition Memory in Young Adult Females in an Experimental Model

open access: yesMolecular Nutrition &Food Research, Volume 70, Issue 17, 15 September 2026.
Our study investigates the effects of perinatal supplementation with lutein, DHA, and choline in a controlled rat model. The results show: (1) strictly sex‐specific effects exclusively observed in female rats, (2) lutein‐dependent and synergistic effects, (3) enhancement of long‐term recognition memory, and (4) no effects on locomotor activity, anxiety‐
Leon Saschin   +13 more
wiley   +1 more source

Biosynthesis of essential fatty acids in Octopus vulgaris (Cuvier, 1797): Molecular cloning, functional characterisation and tissue distribution of a fatty acyl elongase [PDF]

open access: yes, 2012
Polyunsaturated fatty acids (PUFA) have been identified as key nutrients for the common octopus (Octopus vulgaris), particularly for its early life-cycle stages (paralarvae).
Hontoria, Francisco   +6 more
core   +1 more source

Stimulating proteasomal degradation in human proteinopathies

open access: yesThe FEBS Journal, Volume 293, Issue 18, Page 5514-5540, September 2026.
The proteasome mediates the degradation of a wide range of proteins. Boosting proteasomal degradation may be beneficial in several disease contexts and can be achieved either by modulating proteasome activity or by improving substrate delivery. Proteasome activity can be enhanced by increasing proteasome abundance, inducing constitutive gate opening ...
Maria E. Gierisch   +2 more
wiley   +1 more source

Systems‐Level Plant Responses Reveal Pseudomonas‐Mediated Growth Promotion in Brachypodium Under Nitrogen Limitation

open access: yesPlant, Cell &Environment, Volume 49, Issue 9, Page 6396-6412, September 2026.
ABSTRACT Plant growth–promoting bacteria can enhance plant performance under nutrient limitation, yet the underlying plant molecular responses remain incompletely resolved. We investigated growth promotion by Pseudomonas koreensis in Brachypodium distachyon under contrasting nitrogen (N) regimes using time‐resolved phenotyping, elemental analysis ...
Stefan Sanow   +12 more
wiley   +1 more source

Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein

open access: yesJournal of Lipid Research, 2010
Compared with other mammalian tissues, retina is highly enriched in PUFA. Long-chain PUFA (LC-PUFA; C18-C24) are essential FAs that are enriched in the retina and are necessary for maintenance of normal retinal development and function. The retina, brain,
Martin-Paul Agbaga   +2 more
doaj   +1 more source

Temperature Differentially Affects Gene Expression in Antarctic Thraustochytrid Oblongichytrium sp. RT2316-13

open access: yesMarine Drugs, 2020
Oblongichytrium RT2316-13 synthesizes lipids rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The content of these fatty acids in the total lipids depended on growth temperature.
Paris Paredes   +7 more
doaj   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

open access: yesAdvanced Science, Volume 13, Issue 43, 3 August 2026.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing   +9 more
wiley   +1 more source

Assessing the Impact of Multigene Engineering on the Proteome: Omega‐3 Camelina as a Case Study

open access: yes
Plant Biotechnology Journal, Volume 24, Issue 10, Page 5480-5482, October 2026.
Hongtao Zhang   +2 more
wiley   +1 more source

Diversification of substrate specificities in teleostei Fads2: characterization of Δ4 and Δ6Δ5 desaturases of Chirostoma estor[S]

open access: yesJournal of Lipid Research, 2014
Currently existing data show that the capability for long-chain PUFA (LC-PUFA) biosynthesis in teleost fish is more diverse than in other vertebrates.
Jorge Fonseca-Madrigal   +5 more
doaj   +1 more source

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