Results 1 to 10 of about 1,306,741 (401)
Modeling mammalian gastrulation with embryonic stem cells [PDF]
arXiv, 2017Understanding cell fate patterning and morphogenesis in the mammalian embryo remains a formidable challenge. Recently, in vivo models based on embryonic stem cells (ESCs) have emerged as complementary methods to quantitatively dissect the physical and molecular processes that shape the embryo.
Amita+65 more
arxiv +3 more sources
Cell Proliferation, 2004
Abstract. Embryonic stem cells have huge potential in the field of tissue engineering and regenerative medicine as they hold the capacity to produce every type of cell and tissue in the body. In theory, the treatment of human disease could be revolutionized by the ability to generate any cell, tissue, or even organ, ‘on demand’ in the laboratory. This
Anne E. Bishop, Helen J. Rippon
openaire +5 more sources
Abstract. Embryonic stem cells have huge potential in the field of tissue engineering and regenerative medicine as they hold the capacity to produce every type of cell and tissue in the body. In theory, the treatment of human disease could be revolutionized by the ability to generate any cell, tissue, or even organ, ‘on demand’ in the laboratory. This
Anne E. Bishop, Helen J. Rippon
openaire +5 more sources
Discover Oncology, 2023
Background The incidence of ovarian cancer ranks third among gynecologic malignancies, but the mortality rate ranks first. Methods The expression of GAS5 is low in ovarian cancer and is associated with the low survival of ovarian cancer patients ...
Te Zhang+18 more
doaj +1 more source
Background The incidence of ovarian cancer ranks third among gynecologic malignancies, but the mortality rate ranks first. Methods The expression of GAS5 is low in ovarian cancer and is associated with the low survival of ovarian cancer patients ...
Te Zhang+18 more
doaj +1 more source
NSUN2 alleviates doxorubicin-induced myocardial injury through Nrf2-mediated antioxidant stress
Cell Death Discovery, 2023Doxorubicin (DOX) is a commonly used antitumor drug, but its application has been limited because of its strong cardiac damage. This study aims to explore the role of NSUN2 in DOX-induced heart injury.
Yi Wang+13 more
doaj +1 more source
Targeting of Embryonic Stem Cells by Peptide-Conjugated Quantum Dots [PDF]
, 2010Targeting stem cells holds great potential for studying the embryonic stem cell and development of stem cell-based regenerative medicine. Previous studies demonstrated that nanoparticles can serve as a robust platform for gene delivery, non-invasive cell
Li, Lin Song+8 more
core +11 more sources
Microorganisms, 2023
Raoultella ornithinolytica is an Enterobacteriaceae bacterium that can infect both humans and animals, while luteolin-7-O-glucoside (IOG) is a flavonoid that has broad effects on the intestinal microbiota of healthy animals. However, current studies lack
Zhaomeng Wu+5 more
doaj +1 more source
Raoultella ornithinolytica is an Enterobacteriaceae bacterium that can infect both humans and animals, while luteolin-7-O-glucoside (IOG) is a flavonoid that has broad effects on the intestinal microbiota of healthy animals. However, current studies lack
Zhaomeng Wu+5 more
doaj +1 more source
FEBS Open Bio, 2021
MicroRNAs (MiRNAs) play critical roles in regulating target gene expression and multiple cellular processes in human cancer malignant progression. However, the function of miR‐194 in gastric cancer (GC) remains unclear and controversial.
Jingjie Wang+6 more
doaj +1 more source
MicroRNAs (MiRNAs) play critical roles in regulating target gene expression and multiple cellular processes in human cancer malignant progression. However, the function of miR‐194 in gastric cancer (GC) remains unclear and controversial.
Jingjie Wang+6 more
doaj +1 more source
Embryonic Stem Cells in Cattle [PDF]
Reproduction in Domestic Animals, 2008ContentsBecause of the potential use of embryonic stem cells (ESC), especially for genetic modifications, there is great interest in establishing domestic animals‐related ESCs. Unfortunately, despite considerable efforts, validated ESC lines in species other than mice and primates are yet to be isolated.
Enrique J. Gómez+7 more
openaire +5 more sources
Subventricular zone stem cells are heterogeneous with respect to their embryonic origins and neurogenic fates in the adult olfactory bulb [PDF]
, 2007Wedetermined the embryonic origins of adult forebrain subventricular zone (SVZ) stem cells by Cre-lox fate mapping in transgenic mice. We found that all parts of the telencephalic neuroepithelium, including the medial ganglionic eminence and lateral ...
Fogarty, M+3 more
core +4 more sources
Stem Cell Research & Therapy, 2021
Aims Neointimal hyperplasia remains a major obstacle in vascular regeneration. Sca-1-positive progenitor cells residing within the vascular adventitia play a crucial role in the assemblage of vascular smooth muscle cell (VSMC) and the formation of the ...
Yan Wu+17 more
doaj +1 more source
Aims Neointimal hyperplasia remains a major obstacle in vascular regeneration. Sca-1-positive progenitor cells residing within the vascular adventitia play a crucial role in the assemblage of vascular smooth muscle cell (VSMC) and the formation of the ...
Yan Wu+17 more
doaj +1 more source