Results 1 to 10 of about 1,324,654 (403)
Derivation of completely cell culture-derived mice from early-passage embryonic stem cells. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1993 Several newly generated mouse embryonic stem (ES) cell lines were tested for their ability to produce completely ES cell-derived mice at early passage numbers by ES cell tetraploid embryo aggregation.
A. Nagy +4 more
semanticscholar +2 more sources
Modeling mammalian gastrulation with embryonic stem cells [PDF]
arXiv, 2017 Understanding cell fate patterning and morphogenesis in the mammalian embryo remains a formidable challenge. Recently, in vivo models based on embryonic stem cells (ESCs) have emerged as complementary methods to quantitatively dissect the physical and molecular processes that shape the embryo.
Amita +65 more
arxiv +3 more sources
Developmental Biology, 2000 Embryonic stem (ES) cell lines derived from human blastocysts have the developmental potential to form derivatives of all three embryonic germ layers even after prolonged culture.
M. Amit +7 more
semanticscholar +2 more sources
Cell Proliferation, 2004 Abstract. Embryonic stem cells have huge potential in the field of tissue engineering and regenerative medicine as they hold the capacity to produce every type of cell and tissue in the body. In theory, the treatment of human disease could be revolutionized by the ability to generate any cell, tissue, or even organ, ‘on demand’ in the laboratory. This
Anne E. Bishop, Helen J. Rippon
openaire +5 more sources
The Journal of Pathology, 2002 AbstractThe capacity of embryonic stem cells for virtually unlimited self‐renewal and differentiation capacity has opened up the prospect of widespread applications in biomedical research and regenerative medicine. For the latter, the cells provide hope that it will be possible to overcome the problems of donor tissue shortage and also, by making the ...
Anne E. Bishop +2 more
openaire +3 more sources
Discover Oncology, 2023 Background The incidence of ovarian cancer ranks third among gynecologic malignancies, but the mortality rate ranks first. Methods The expression of GAS5 is low in ovarian cancer and is associated with the low survival of ovarian cancer patients ...
Te Zhang +18 more
doaj +1 more source
NSUN2 alleviates doxorubicin-induced myocardial injury through Nrf2-mediated antioxidant stress
Cell Death Discovery, 2023 Doxorubicin (DOX) is a commonly used antitumor drug, but its application has been limited because of its strong cardiac damage. This study aims to explore the role of NSUN2 in DOX-induced heart injury.
Yi Wang +13 more
doaj +1 more source
Targeting of Embryonic Stem Cells by Peptide-Conjugated Quantum Dots [PDF]
, 2010 Targeting stem cells holds great potential for studying the embryonic stem cell and development of stem cell-based regenerative medicine. Previous studies demonstrated that nanoparticles can serve as a robust platform for gene delivery, non-invasive cell
Li, Lin Song +8 more
core +11 more sources
Microorganisms, 2023 Raoultella ornithinolytica is an Enterobacteriaceae bacterium that can infect both humans and animals, while luteolin-7-O-glucoside (IOG) is a flavonoid that has broad effects on the intestinal microbiota of healthy animals. However, current studies lack
Zhaomeng Wu +5 more
doaj +1 more source
Embryonic Stem Cells in Cattle [PDF]
Reproduction in Domestic Animals, 2008 ContentsBecause of the potential use of embryonic stem cells (ESC), especially for genetic modifications, there is great interest in establishing domestic animals‐related ESCs. Unfortunately, despite considerable efforts, validated ESC lines in species other than mice and primates are yet to be isolated.
Enrique J. Gómez +7 more
openaire +6 more sources