Results 21 to 30 of about 1,123,946 (363)

Embryonic Stem Cell Markers [PDF]

Molecules, 2012
Embryonic stem cell (ESC) markers are molecules specifically expressed in ES cells. Understanding of the functions of these markers is critical for characterization and elucidation for the mechanism of ESC pluripotent maintenance and self-renewal, therefore helping to accelerate the clinical application of ES cells.
Wenxiu Zhao, Fangfang Zhang, Liang Li, Xiang Ji, Lan Ma   +4 more
openaire   +4 more sources

Brain magnetic resonance imaging predictors in anti‐N‐methyl‐D‐aspartate receptor encephalitis

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1974-1984, December 2022., 2022
Abstract Objective Brain magnetic resonance imaging (MRI) findings in anti‐N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis are nonspecific and rarely have obvious associations with clinical characteristics and outcomes. This study aimed to comprehensively describe the MRI features of patients with NMDAR encephalitis, examine their associations with ...
Ying‐Ying Zhao, Bing Han, Cui‐Hong Qin, Xue‐Xiu Shi, Wen‐Jing Yun, Meng Wang, Bo Yuan, Tong‐Wen Sun, Hai‐Xu Wang   +8 more
wiley   +1 more source

Qiliqiangxin reduced cardiomyocytes apotosis and improved heart function in infarcted heart through Pink1/Parkin -mediated mitochondrial autophagy

BMC Complementary Medicine and Therapies, 2020
Background Qiliqiangxin (QLQX) is a preparation refined from a traditional Chinese medicine compound. It plays an important role in protecting cardiac function after myocardial infarction (MI). However, the underline mechanism of QLQX action is not clear.
Junyang Zhou, Zhixiao Wang, Yun He, Xinxia Luo, Wenjun Zhang, Li Yu, Xiuying Chen, Xiju He, Yahong Yuan, Xiaoli Wang, Xinrong Guo, Junming Tang, Mingan Zhu, Dongsheng Li, Yan Ding   +14 more
doaj   +1 more source

An Efficient and Footprint-Free Protocol for the Transdifferentiation of Hepatocytes Into Insulin-Producing Cells With IVT mRNAs

Frontiers in Genetics, 2020
BackgroundDirect transdifferentiation of adult somatic cells into insulin-producing cells (IPCs) is a promising approach for cell-based therapies for type 1 diabetes mellitus.
Shinan Ma, Mengjie Yang, Mengjie Yang, Wenhui Zhou, Longjun Dai, Longjun Dai, Yan Ding, Xingrong Guo, Yahong Yuan, Junming Tang, Dongsheng Li, Xiaoli Wang   +11 more
doaj   +1 more source

Chicken embryonic stem cells as a non‐mammalian embryonic stem cell model [PDF]

Development, Growth & Differentiation, 2010
Embryonic stem cells (ESCs) were isolated in the early 1980s from mouse and in the late 1990s from primate and human. These cells present the unique property of self‐renewal and the ability to generate differentiated progeny in all embryonic lineages both in vitro and in vivo.
Fabrice Lavial, Bertrand Pain, Bertrand Pain   +2 more
openaire   +5 more sources

ANGPTL8 promotes adipogenic differentiation of mesenchymal stem cells: potential role in ectopic lipid deposition

Frontiers in Endocrinology, 2022
BackgroundEctopic lipid deposition plays a promoting role in many chronic metabolic diseases. Abnormal adipogenic differentiation of mesenchymal stem cells (MSCs) is an important cause of lipid deposition in organs.
Jian Tang, Jian Tang, Shinan Ma, Yujiu Gao, Fan Zeng, Ying Feng, Chong Guo, Lin Hu, Lingling Yang, Lingling Yang, Yanghui Chen, Qiufang Zhang, Yahong Yuan, Xingrong Guo, Xingrong Guo   +14 more
doaj   +1 more source

Generation of C57BL/6 knockout mice using C3H × BALB/c blastocysts

BioTechniques, 2008
The International Mouse Knockout Consortium aims to generate a knockout mouse for every single gene on a C57BL/6 background. Our ability to generate such mice is hampered by the poor economics of producing blastocysts to achieve germline transmission of ...
Gabriela Pacholczyk, Rupali Suhag, Magdalena Mazurek, Suzanne M. Dederscheck, Pandelakis A. Koni   +4 more
doaj   +1 more source

No association between myeloperoxidase gene rs2333227 G>A polymorphism and Alzheimer's disease risk: a meta-analysis and trial sequential analysis [PDF]

Journal of Integrative Neuroscience, 2022
Evidence suggests that there is a close association between myeloperoxidase (MPO) gene rs2333227 G>A polymorphism with Alzheimer’s disease (AD) susceptibility.
Zhi-Cheng Fang, Chen-Chen Mao, Ya-Jun Hu, Gong-Li Yang, Lan Zhou   +4 more
doaj   +1 more source

ANGPTL8 is a negative regulator in pathological cardiac hypertrophy

Cell Death and Disease, 2022
Pathological cardiac hypertrophy is an independent risk factor for heart failure and is considered a target for the treatment of heart failure. However, the mechanisms underlying pathological cardiac hypertrophy remain largely unknown.
Lin Hu, Jiarui Wei, Yue Zhang, Ziyuan Wang, Junming Tang, Jian Tang, Yujiu Gao, Xiaoqiao Zhang, Yifan Li, Yantong Liu, Shinan Ma, Xingrong Guo, Qiufang Zhang   +12 more
doaj   +1 more source

Embryonic Stem Cell.

Internal Medicine, 2001
Mouse embryonic stem (ES) cells are the cells that possess pluripotential differentiation activity into not only all somatic cells but also germ cells. Genetic alteration of mouse ES cells can be easily achieved and such genetic modification can be introduced into the animal, since ES cells are differentiated into germ cells in vivo.
Masatake Sato, Toru Nakano
openaire   +4 more sources